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PATHO SKIN
| Question | Answer |
|---|---|
| Neoplasm of melanocytes Tan-brown uniformly pigmented, small macules or papules with well-defined rounded borders | MELANOCYTIC NEVUS or PIGMENTED NEVUS |
| Most deadly of all skin cancers borders are irregular and often notched clinical signs are changes in the color, size, or shape of a pigmented lesion | MELANOMA |
| Small, round, flat, pore-like ostia impacted with keratin; coin-like plaques Uniformly tan-brown with velvety to granular surface --> receptor-3 (FGFR3) | SEBORRHEIC KERATOSES |
| 2nd most common tumor arising on sun-exposed sites In situ carcinoma appear as red scaling plaques Advanced lesions are nodular and may ulcerate --> p53 | SQUAMOUS CELL CARCINOMA |
| Most common invasive cancer in humans Slow-growing tumors, rarely metastasize Have a tendency to occur at sun-exposed sites & in lightly pigmented people pearly papules often containing prominent, dilated subepidermal blood vessel | BASAL CELL CARCINOMA |
| Squamoproliferative disorders caused by human papillomaviruses Direct contact between individuals or autoinoculation Generally self-limited, regressing spontaneously within 6 months to 2 years | VERRUCAE (WARTS) |
| the most common type of wart occur on the hands, particularly on the dorsal surfaces and periungual areas | Verruca vulgaris |
| face or the dorsal surfaces of the hands slightly elevated, flat, smooth, tan papules | Verruca plana, or flat wart |
| occur on the soles and palms, respectively | Verruca plantaris and verruca palmaris |
| occurs on the penis, female genitalia, urethra, perianal areas, and rectum caused by HPV 6 and 11 | Condyloma acuminatum or venereal wart |
| Inflammation of the oral mucosa Gingival erythema, edema, bleeding, changes in contour, and loss of soft tissue adaptation to the teeth | GINGIVITIS |
| Inflammatory process that affects the supporting structures of the teeth, alveolar bone, and cementum | PERIODONTITIS |
| Most common fungal infection of the oral cavity Immune status of the individual, the strain of C. albicans present, and the composition of an individual’s oral flora | ORAL CANDIDIASIS |
| “Thrush” Superficial, gray to white inflammatory membrane composed of matted organisms enmeshed in a fibrinosuppurative exudate that can be readily scraped off to reveal an underlying erythematous inflammatory base | ORAL CANDIDIASIS PSEUDOMEMBRANOUS FORM |
| Earliest lesion Nests of round cells that grow along the dermoepidermal junction | Junctional nevi |
| Nevi cells are seen entirely in the dermis | Intradermal Nevi |
| Nests of nevi cells are seen within the dermis and dermoepidermal junction | Compound Nevi |
| Sticky, colorless, biofilm that collects between and on the surface of the teeth Mixture of bacteria, salivary proteins, and desquamated Epithelial cells | Dental plaque |
| Multiple basal cell carcinomas accompanied by tumors, odontogenic keratocysts, and pits of the palms and soles | Nevoid basal cell carcinoma syndrome Gorlin syndrome |
| abrupt onset of vesicles and ulcerations of the oral mucosa with lymphadenopathy, fever, anorexia, and irritability | Acute herpetic gingivostomatitis |
| ODONTOGENIC CYSTS: originates around the crown of an unerupted tooth Radiographically, they are unilocular lesions and are most often associated with impacted third molar (wisdom) teeth | Dentigerous Cyst |
| ODONTOGENIC CYSTS: Occur most frequently in the third molar region of the mandible Radiographically- unilocular or multilocular radiolucencies | Odontogenic Keratocyst (OKC) |
| ODONTOGENIC CYSTS: Most frequently encountered cyst of the jaws Inflammatory in origin Extremely common lesions found at the apex of teeth The inflammatory process may give rise to a periapical abscess | Radicular Or Periapical Cyst |
| Arises from odontogenic epithelium Commonly cystic, slow growing, and locally invasive but has an indolent course | Ameloblastoma |
| Odontogenic tumors featuring production of calcified parts of teeth Arises from epithelium but shows extensive depositions of enamel and dentin Usually occur in the alveolar ridge of the mandible or maxilla | Odontoma |
| “A white patch or plaque that cannot be scraped off and cannot be characterized clinically or pathologically as any other disease” | LEUKOPLAKIA |