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pharm chapter 25
| Question | Answer |
|---|---|
| geneder/age most common for thyroid disroders | women agesd20-40 |
| Thyroid-stimulating hormone | A hormone released by the pituitary gland that stimulates the thyroid gland to produce and release thyroid hormones |
| hypothyroidism | high TSH LEVELS |
| Radioactive iodine uptake (RAIU) test | TEST FOR THYROID DISEASE measures how much radioactive iodine the thyroid gland absorbs. Since the thyroid uses iodine to produce hormones (T3 and T4), high - hyperthroidism low- hypo low- hypothyroidism |
| Hyperthyroidism | A condition in which there is an excessive production of thyroid hormones -enlarged/overactive thyroid , low tsh levels , pituitary gland works less |
| radioactive iodine | high doses administered for treatment hyperthyroidism blocks the making of thyroid hormone - requires lifelong therapy for hypothyroidism can cause thyroid damage in developing fetus - no pregnancy |
| thioamides | used to treat HYPERTHYROIDISM reduces excess thyroid hormone/ block T3,+ T4 |
| autoimmune thyroiditis | body produces antibodies to its own thyroid cells |
| Hypothyroidism | Thyroid gland secretes deficient amounts of thyroid hormones high amounts of TSH/ meaning pituitary gland works harder . thyroid gland is therefor underactive |
| Hormone replacement therapy | treatment for hypothyroidism - uses synthetic levothyroxine (T4) to replace the missing thyroid hormone levothyroxine is standard - permanent life long treatment |
| synthetic t4 | levothyroxine - converted to liothyronine in the body - typically Monotherapy |
| Liothyronine | synthetic t3 prescribed when rapid correction of hypothyroid symptoms is needed |
| methimazole | first-line pharmacological treatment for hyperthyroidism blocks enzyme producing t3 and t4 It does this by inhibiting the enzyme thyroid peroxidase |
| Liotrix (T4:T3) | A synthetic combination of thyroxine (T4) and triiodothyronine (T3) treats hypothyroidism |
| Desiccated thyroid | a powdered, dried animal thyroid extract (usually pig) used to treat hypothyroidism, containing both T4 and T3 hormones, offering a "natural" alternative to synthetic hormones like levothyroxine- treatment for hypothyroidism |
| Warning Labels: Treatment of Hyperthyroidism | Avoid pregnancy •Take on an empty stomach or with food, but for consistent effects always take it the same way (thioamides |
| thyroid peroxidase | enzyme blocked that produced T3/t4 in treating hyperthyroidism with methimazole |