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genetics chapter 19
eukaryotic gene expression
| Question | Answer |
|---|---|
| what is chromatin and how does it affect transcription? | |
| how does RNA processing differ in the different cell types? | |
| what does the promoter look like in eukaryotic cells? | |
| what is an enhancer? | |
| where can enhancers be found? how many can a gene have? | |
| what is a transcription factor? | |
| what is a basal factor? | |
| what is a mediator? | |
| what is an activator? | |
| how do activators increase transcription? | |
| what kinds of domains do activators have? | |
| what is a helix-turn-helix motif? | |
| what is a zinc finger? | |
| what is a dimerization domain? | |
| what is a leucine zipper? | |
| what is a repressor? how does it work? | |
| what is an indirect repressor? | |
| what are the ways that indirect repressors inhibit the actions of an activator? | |
| how is chromatin modified? | |
| what is methylation? | |
| what is acetylation? | |
| what enzymes modify in these ways? | |
| what does adding methyl groups to histones do? | |
| what does adding acetyl groups to histones do? | |
| can a gene have more than one enhancer? | |
| can an enhancer have more than one binding site? | |
| what are allosteric interactions? | |
| how are transcription factors modified and therefore regulated? | |
| how are various genes of the same pathway controlled in eukaryotes? | |
| how do enhancers know what gene to control if they can be several thousand base pairs away from a promoter? | |
| what is an insulator? how does it work? | |
| what is alternative splicing and how is it controlled? | |
| how does the eukaryotic initiation factor and the binding protein influence translation? | |
| how does the length of the poly A tail influence the translation of a particular mRNA? | |
| what small RNAs are found in eukaryotic cells and what do each do? | |
| how do miRNAs work? | |
| how do siRNAs work? | |
| how do piRNAs work? | |
| what are argonaute proteins and what do they do? | |
| what kind of post-translational modifications can occur to control protein activity? |