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Pharm Final
| Question | Answer |
|---|---|
| What is the opioid ceiling effect? | When drug reaches a maximum effect |
| How much more potent is hydromorphone than morphine? | Seven times |
| What are the contraindications for opioids? | Known drug allergy and severe asthma |
| What patients should opioids be used with caution? | Respiratory insufficiency, obesity, sleep apnea, pregnancy |
| What are the two main adverse effects of opioids? | Respiratory depression and constipation |
| What is the antidote to an opioid? | Narcan |
| What do opioids interact with? | Alcohol, antihistamines, barbiturates, and benzodiazepines |
| What type of effects does Tylenol not have? | Antiinflammatory |
| What is the maximum daily dose for a healthy adult of acetaminophen? | 3000 |
| What is the maximum daily dose of acetaminophen for an older adult or those with liver disease? | 2000 |
| What is the contraindication for acetaminophen? | Liver dysfunction |
| What does acetaminophen interact with? | Alcohol |
| What is the antidote for acetaminophen? | Acetylcysteine |
| What makes Tylenol and ibuprofen different? | Ibuprofen has anti-inflammatory effects |
| What are the contraindications of nsaids? | Known drug allergy (aspirin), vitamin K deficiency, and peptic ulcer disease (higher risk for bleeding) |
| What are the adverse effects of NSAIDS? | GI, renal failure, increase risk of MI/stroke |
| What are the interactions with NSAIDS? | Anticoagulants and aspirin |