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Anthony O. Nwaobi

Physiology Week 7 -13

QuestionAnswer
Proximal Tubule Function Reabsorbs 80–90% of filtered bicarbonate (HCO₃⁻) through CO₂/H₂O conversion and H⁺ secretion.
Which organ provides long-term correction of acid–base disturbances? The kidneys.
Intercalated Cells (Collecting Duct) Specialized cells that adjust H⁺ secretion or HCO₃⁻ reabsorption to fine-tune blood pH.
Which hormones increase renal hydrogen ion secretion? Aldosterone and angiotensin II.
What happens to blood pH when hydrogen ion concentration increases? pH decreases (acidosis).
Metabolic Acidosis A decrease in blood pH due to loss of bicarbonate or excess acid production (e.g., renal failure, diarrhea).
Respiratory Acidosis A pH decrease caused by CO₂ retention from hypoventilation.
Metabolic Alkalosis A rise in blood pH due to excess bicarbonate or loss of acid (e.g., vomiting).
What blood pH range is considered normal? 7.35–7.45.
How does high plasma potassium affect renal acid secretion? High K⁺ reduces H⁺ secretion, decreasing acid elimination.
Created by: tony4real
 

 



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