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CNS 1
BDK
| Generic Name | Brand Name | Pharmacologic Category | Common Indications | Key Side Effects | Other Notes | US Boxed Warnings | Classification |
|---|---|---|---|---|---|---|---|
| Mirtazapine | Remeron | Alpha2 antagonist | MDD | Drowsiness, Weight gain, Xerostomia, Increased appetite, Constipation | N/A | Increased risk of suicidal thinking & behavior in children, adolescents, & young adults | N/A |
| Bupropion | Wellbutrin SR, Wellbutrin XL | NE-DA reuptake inhibitor | MDD | Tachycardia, Headache, Agitation, Dizziness, Insomnia, Weight loss, Xerostomia | Use may increase risk of seizures (CI in patients w/ seizure disorders and/or eating disorders) | Serious neuropsychiatric reactions have occurred; increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Atomoxetine | Strattera | Selective NE reuptake inhibitor | ADHD | HTN, Tachycardia, Headache, Xerostomia, Nausea, Vomiting, Constipation, Decreased appetite, Insomnia | CI within 14 days of MAOI | Increased risk of suicidal ideation in children or adolescents | N/A |
| Desvenlafaxine | Pristiq | Serotonin-NE reuptake inhibitor (SNRI) | MDD | Headache, Xerostomia, Nausea, Vomiting, Constipation, Decreased appetite, Insomnia, Diaphoresis, HTN, Sexual dysfunction | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Venlafaxine | Effexor XR | Serotonin-NE reuptake inhibitor (SNRI) | MDD | Headache, Xerostomia, Nausea, Vomiting, Constipation, Decreased appetite, Insomnia, Diaphoresis, HTN, Sexual dysfunction | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Duloxetine | Cymbalta | Serotonin-NE reuptake inhibitor (SNRI) | MDD, neuropathic pain | Headache, Xerostomia, Nausea, Vomiting, Constipation, Decreased appetite, Insomnia, Diaphoresis, HTN, Sexual dysfunction | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Citalopram | Celexa | Selective serotonin reuptake inhibitor (SSRI) | MDD | Drowsiness, Insomnia, Nausea, Vomiting, Xerostomia, Sexual dysfunction, Headache, Diaphoresis | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Fluoxetine | Prozac | Selective serotonin reuptake inhibitor (SSRI) | MDD | Drowsiness, Insomnia, Nausea, Vomiting, Xerostomia, Sexual dysfunction, Headache, Diaphoresis | CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Escitalopram | Lexapro | Selective serotonin reuptake inhibitor (SSRI) | MDD | Drowsiness, Insomnia, Nausea, Vomiting, Xerostomia, Sexual dysfunction, Headache, Diaphoresis | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Paroxetine | Paxil | Selective serotonin reuptake inhibitor (SSRI) | MDD | Drowsiness, Insomnia, Nausea, Vomiting, Xerostomia, Sexual dysfunction, Headache, Diaphoresis | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Sertraline | Zoloft | Selective serotonin reuptake inhibitor (SSRI) | MDD | Drowsiness, Insomnia, Nausea, Vomiting, Xerostomia, Sexual dysfunction, Headache, Diaphoresis | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Trazodone | Desyrel | Serotonin reuptake inhibitor | Insomnia, MDD | Priapism, Sedation, Headache, Dizziness, Xerostomia, Nausea | N/A | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Amitriptyline | Elavil | Tricyclic antidepressant (TCA) | MDD, diabetic neuropathy, migraine prophylaxis | Dizziness, Drowsiness, Orthostatic hypotension, Sexual dysfunction, Xerostomia, Blurred vision, Constipation | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Nortriptyline | Pamelor | Tricyclic antidepressant (TCA) | MDD, diabetic neuropathy, migraine prophylaxis | Dizziness, Drowsiness, Orthostatic hypotension, Sexual dysfunction, Xerostomia, Blurred vision, Constipation | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |
| Doxepin | Silenor | Tricyclic antidepressant (TCA) | Insomnia | Somnolence, Sedation, Nausea | Don't discontinue abruptly; CI within 14 days of MAOI | Increased risk of suicidal thinking and behavior in children, adolescents, and young adults | N/A |