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Exam 4

QuestionAnswer
Muscle System Functions movement, protect, maintain posture, valves, stabilizes joints, control pupil size, heat (contract), & goosebumps
Epimysium sheath of dense, irr. CT covering the entire muscle
Perimysium middle layer surrounding fascicle
Endomysium A thin CT of collagen & reticular fibers surrounding each muscle fiber/cell
Skeletal Muscle made out of muscle fascicles
Muscle Fibers made out of myofibrils
Smooth Reticulum (SR) smooth ER that stores, releases, & retrieve Ca++
T-tubules sarcolemma extensions into deep of the muscle fiber
Terminal Cisternae SR that adjacent to T tubule
Triad 2 terminal cistenae
I band light band
MT features Excitability, Elasticity, Extensibility, & Contractibility
Excitability sends an electrical wave (action potential along the entire length of membrane)
Extensibility stretch/expand
Elasticity return back to its original length
Contractibility pull on attachment points & shorten with force
Neuromuscular Junction site where a motor neuron's terminal meets the muscle fibers
NMJ 1st step neural action potential arrives @ NMJ
NMJ 2nd step Axon releases neurotransmitter ACh
NMJ 3rd step ACh diffuse to synaptic cleft & bind to ACh receptors at motor end plate
NMJ 4th step Depolarization: Na+ channels open (end plate potential) and Na come in to the muscle
NMJ 5th step triggers voltage-gated channel Na+ channels to open along the Sarcolemma, creating a muscle action potential that spread across the entire muscle fiber
NMJ 6th step The action potential travels along down the T-tubules, reaching the SR
NMJ 7th step SR release Ca++ from voltage gated channels into the sarcoplasm to start contraction
NMJ 8th step The enzyme acetylcholinesterase (AChE) breaks down ACh so the muscle doesn’t stay contracted.
NMJ 9th step repolarization
Muscle Fiber Contraction When Ca++ is released from SR, it binds to troponin, Myosin heads attach. When ATP binds, it detach from action, and process is repeat
Sarcomere smallest contractile unit in the muscle fiber
Motor Signal signal for contraction to muscle
Contraction release Ca++ from SR
Motor Unit Both neuron & the muscle fibers it innervate (deliver the signals)
Motor neuron carry the motor signal; can send the same signal for multiple muscles
Neuromuscular Junction connection between the motor neuron & muscle
Tropomyosin acts as the physical barrier between actin and myosin
ATP needed to break the cross-bridge
Power stroke Myosin pulls actin towards the M line
Power stroke When ADP runs out, Myosin rapidly snaps back to its default position
Ca++ pump move Ca++ back to SR
Muscle Twitch Latent (Excitation) Period , Contraction Period, & Relaxation Period
Muscle Twitch one contraction from one action potential
Latent period time needed to open Na+ gate @ motor-end plate generate ATP, motive it down to T-tubue & relaxes Ca++ ions; AP is being propagated along the Sarcolemma & Ca++ is being released from the SR (5mm sec)
Contraction period Cross-bridge cycle (20mm sec)
Relaxation period Time needed to pump Ca++ back to SR
ATP pump Ca++ back to SR
ATP Na+/K+ pump
Creatine Phosphate Fast way to produce ATP; short lasting (40 sec) & emergency use
Aerobic Respiration require O2, uses glucose, fat/lipids & proteins to generate ATP; 1 glucose - 32 ATP; takes very long time
Anaerobic Respiration works in low O2 conditions; only use glucose; 1 glucose - 2 ATP; Fast in producing ATP but unsustainable
Excitation Ca++ out of the SR
Relaxation Ca+ pump move Ca++ back to SR; Troponin restore its shape & Tropomyosin blocks myosin from actin
MP Depolarization Contraction; Na+ enter; inside is less negative/positive
MP Repolarization Relaxation; K+ exit; inside goes back to negative
Vesicles inside the axon terminals; contains Acetylcholine ACh
Na+ gated channels rest on the Sarcolemma
Ca++ gated channels rest on the axon terminal
MP at rest + out & - in; Na+ out & K+ in; -70 mV
Sliding Filament Model Myosin pulls the actin toward the M line during contraction
Created by: FuirzH
 

 



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