Save
Upgrade to remove ads
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Infection drugs

Antiviral, Antitubercular, Antifungal Drugs

QuestionAnswer
How do antiviral drugs work? Block the activity of the polymerase enzyme, which is used to replicate the virus and spread.
What do antiviral drugs treat? Non-HIV viral infections - VZV, HSV, influenza viruses, CMV, Hepatitis A, B, C
Acyclovir Treats HSV 1, HSV 2, VZV Available in PO, IV, and topical form **** Nephrotoxic***
Oseltamivir phosphate "Tamiflu" Treats type A&B influenza PO only
Side effects of Oseltamivir phosphate Nausea and Vomiting
Zanamivir "Relenza" Treats type A&B influenza Inhalation drug
Side effects of Zanamivir Nausea Vomiting Sinusitis
When should Influenza treatment drugs begin? Within 2 days of influenza symptom onset
Ribavirin "Virazole" Treatment of Hep. C PO or nasal *inhalation also used for infants with respirator syncytial virus infections.
Antitubercular Drugs Given for 6-12 months 2-4 antibiotics used ***Asses liver function***
What are the first line antitubercular drugs? Rifampin Isoniazid Prazinamide Ethambutol hydrochloride
What are the second-line antitubercular drugs? Amikacin Sulfate Levofloxacin Hemihydrate Moxifloxacin hydrochloride
Isoniazid "Isotamine" Drug of choice Side effect of hyperglycemia - from the continuous breakdown of the stored glucose
What are the side effects of isoniazid? Hyperglycemia - from the continuous breakdown of the stored glucose Optic neuritis Hepatotoxicity
Ethambutol hydrochloride Bacteriostatic ***concern for renal impairment***
Side effects of Ethambutol hydrochloride Optic neuritis Blindness
Pyrazinamide Bacteriostatic or bactericidal Po
Contraindications for Pyrazinamide Liver disease Gout - Uric acid level Pregnancy
Rifampin Most potent and broad Bactericidal
Side effects of Rifampin Hepatitis Liquids become orange/red Causes oral contraceptives to become ineffective
Bacille calmette-guerin (BCG) Inactive strand Reduces active TB
What are the major categories of antifungal drugs? Imidazoles Triazoles Echinocandins Polyenes
Imidazoles and triazoles Inhibit fungal cell cytochrome P450 enzymes
Echinocandins Prevent glucans - needed for funcal cell walls
Polyenes Bind to sterols in fungal cell membrane
Amphotericin B Broad spectrum antifungal Choice for systemic mycoses Prophylactically for immunosupressed IV only
Side effects Cardiac dysrhythmias Neurotoxicity Kidney toxicity Pulmonary infiltrates
Contraindications of antifungal drugs Liver failure Kidney failure Prophyria
Created by: ahgecas25
 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards