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Psych 3.3

QuestionAnswer
Affective blunting Reduced or constricted affect
Apathy Expressed anhedonia, decreased interest in activities or beliefs that would otherwise be interesting
Alogia Poverty of speech, reduction in speech
Constricted Reduced in range or intensity, i.e showing only sadness or anger and nothing else
ANosognosia The inability to recognize that one is ill
Affective sx Altered experience and expression of emotions. Mood may change rapidly.
Should you debate delusional content? Never debate delusional content
Name the first generation antipsychotics Haloperidol, fluphenazine, chlorpromazine, decanoate
Side effects of first generation antipsychotics Can cause anticholinergic side effects and extrapyramidal effects, along with tardive dyskinesia, weight gain, and sexual dysfunction.
What are the second generation antipsychotics? ripiprazole, risperidone, clozapine, olanzapine, anything that ends in pine or one.
Second generation antipsychotics MOA, what it treats, and sx Serotonin and dopamine receptor antagonists, treats both positive and negative symptoms, has minimal to no EPS or tardive dyskinesia. Tendency for metabolic syndrome.
What is the most used drug for resistant schizophrenia? Clozapine
What are third generation antipsychotics? Aripiprazole, bexipiprazole, cariprazine.
Anticholinergic toxicity side effects Reduced bowel peristalsis, can lead to obstruction, urinary retention, hyperpyrexia without diaphoresis, and delirium.
Side effects of QT prolongation caused by antipsychotics Tachycardia, syncope, seizures, sudden death. Liver impairment occurs in the first few weeks of therapy.
Extrapyramidal side effects (Mild) Akinesia, akathisa, pseudoparkinsonism.
What is akathisa? Restlessness
Mild extrapyramidal side effects can be treated by Benztropine or diphenhydramine
Extrapyramidal side effects (Severe) Acute dystonia, oculogyric crisis.
Severe extrapyramidal side effects should be treated by IV benztropine
What is the presentation, risks, scale used for tardive dyskinesia? Presents as bizarre facial and tongue movements, can cause permanent damage to voluntary muscles, use the AIMS scale
Treatment of tardive dyskinesia Valbenazine and deutetrabenazine
 

 



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