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Chapter 17

Heart

TermDefinition
Alveoli balloon shaped air sacks where gas exchange happens; when you inhale these fill up
Pulmonary Capillaries branches in lungs that surround alveoli
ANP secretes the hearts atria in response to increased blood pressure; produces cardiomyocytes; lowers blood pressure by influencing sodium ion retention in kidneys
Kidneys ANP secretes sodium and water which widens blood vessels, inhibiting a chain reaction
Fibrous Layer tough outer layer (prevents chambers from over filling)
Cardiac Tamponade excess fluid in pericardial cavity, making cavity go inward toward heart
Serous Pericardium houses thin layer of serous fluid called pericardial fluid
Parietal Layer outer layer/fused to fibrous pericardium
Visceral Layer also called epicardium; inner layer; adheres directly to heart; superficial layer of heart wall
Myocardium Layer second layer of heart wall and the thickest
Fibrous Skeleton myocytes pull on during contraction; structural support; electrical insulator
Endocardium Layer third layer of heart wall and the deepest layer
Endothelium what the endocardium layer is made of, simple squamous epithelium
Coronary Circulation vessels that supply myocardium with blood
Anastomose system of channels formed between blood vessels; form when blood flow to myocardium is insufficient
Collateral Circulation alternate routes for blood flow
Plaque fatty material built up in coronary arteries
Angina Pectoris chest pains
Myocardial Ischemia heart muscle does not get enough oxygen-rich blood
Angioplasty procedure to open blocked/narrow arteries
Stenosis closure of a blood vessel or spinal canal
Heart Murmur audible swooshing sound when heart beats; usually effects the mitral and aortic valves (AV valves)
Pacemaker Cells generate action potentials (1%)
1: Initial Depolarization begins in hyperpolarized state (minimum membrane potential)/ non-specific cation channels open/sodium ions enter cell, potassium ions exit
2: Full Depolarization membrane reaches threshold/ voltage-gated calcium ion channels open, calcium enters cell
3: Repolarization calcium ion channels time-gated for closing/potassium ion channels open, potassium ions exit cell/membrane repolarizes
4: Minimum Potential potassium ion channels stay open until membrane reaches minimum potential/cation channels reopen and process begins again
Contractile Cells stimulate action potentials in other cardiac muscle cells (99%)
1: Depolarization voltage-gated sodium ion channels open, sodium enters cell, voltage of membrane goes from negative to positive
2: Initial Repolarization inactivation of sodium ion channels, some potassium channels open, flow out of K+
3: Plateau sustained depolarization/allows calcium channels to stay open, calcium enters cell, potassium continues to exit
Plateau maintains heart rate (time for heart to fill up), prevents tetany (sustained contractions, lengthens refractory period, forces heart to relax between contractions
4: Repolarization sodium and calcium ion channels close, remaining potassium ion channels open, potential returns to -85mV
Cardiac Conduction System group of interconnected pacemaker cells, make action potential throughout the heart
Ectopic Pacemaker contractile cells or other pacemaker cells attempt to pace heart at same time as SA node (irregular heart rhythm)
Dysrhythmia disturbance of normal heart rhythm, disturbance of conduction pathway, and fibrillation
Fibrillation parts of heart depolarizing and contracting while parts repolarizing and not contracting
Arrhythmia no rhythm (flatline)
Atrial Fibrillation not life-threatening irregular heartbeat
Ventricular Fibrillation immediately life-threatening irregular heartbeat (needs defibrillation - electric shock)
Ventricular Filling Phase pressure in left and right ventricles, SL valves closed, no change in volume of heart in ventricles
Isovolumetric Contraction Phase ventricular systole begins, increase in ventricular pressure, AV valves close (S1 produced), SL valves closed, no change in volume in ventricles
Ventricular Ejection Phase begins when ventricular pressure exceeds aortic and pulmonary trunk pressures, SL valves open, blood is ejected from ventricles, aortic and pulmonary trunk pressure rises to match ventricular pressure
Isovolumetric Relaxation Phase ventricular diastole begins, ventricular pressure drops, SL valves close (S2 sound heard), ventricular pressure is still higher than atrial pressure, AV valve remains closed
Wiggers Diagram shows what is happening in the heart at each stage of cardiac cycle
Cardiac Output amount of blood pumped into the pulmonary and systemic circuits in one min
Heart Rate number of cardiac cycles the heart undergoes in one min
Stroke Volume amount of blood pumped with each heartbeat
Preload length of sarcomeres in ventricular muscle cells before contraction
Frank-Starling Law the more ventricular muscle cells are stretched the more forcefully they contract, more actin-myosin overlap,
Contractility increase in stroke volume and decrease in end-systolic volume
Afterload force ventricles must overcome to eject blood, increase corresponds with decrease in stroke volume and increase in end-systolic volume
Ventricular Hypertrophy enlargement of ventricular muscle, heart enlargement which increases other cardiac conditions
Chronotropic Agents influence heart rate
Positive Chronotropic Agents increase heart rate, sympathetic nerves
Negative Chronotropic Agents decreases heart rate, parasympathetic nerves
Inotropic Agents factors that influence contractility, speed up
Cardiomyopathies diseases of the heart muscle
Pulmonary Congestion pulmonary edema
End-diastolic Volume how much blood will hold in ventricles
End-systolic Volume blood remaining in ventricle after it contracts
Created by: user-2005588
 



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