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Clin Med 4 Relearnin

QuestionAnswer
Neisseria Gonorrhea incubation time 2-6d
Other things Neisseria Gonorrhea can cause conjunctivitis, pharyngitis, proctitis
Complications of Neisseria Gonorrhea PID, pregnancy complications, Epididymitis, blood stream infection, increased risk HIV
Chlamydia is hard to culture because its intracellular
Other things Chlamydia may cause conjunctivitis, pharyngitis, proctitis
Lymphogranuloma venerum incubation time 5-21 d
Leading cause of blindness worldwide Trachoma
Worry w Trichomonias in pregnancy preterm, rupture of membranes, small for gestational age
Syphilis lays dormant where CNS
Cryptorchidism complications Increased risk infertility, malignancy, torsion
Klinefelter increased risk for SLE, breast cancer, diabetes, osteoporosis, and other
Most common cause of ejaculatory dysfunction premature ejaculation
Bacterial vaginosis most common cause Gardnerella
Management of BV Metronidazole 500mg BID 7d
Recurrent BV 3+ episodes of BV in 1 yr
Red flags fibroadenoma Skin changes, sanguineous discharge, nipple inversion
Can look like inflammatory carcinoma Mastitis
Increases risk for vulvar cancer Vulvar lichen sclerosis
Complication of vulvar lichen sclerosis midline fusion
What is hydranitis supportiva not due to poor hygiene
Classified by location Leiomyoma
Most common benign neoplasm Leiomyoma
Smoking decreases risk of Endometrial cancer
Pretty good outcome bc easily caught Endometrial cancer
Most common gynecologic malignancy Endometrial cancer
Most common deadly reproductive cancer Ovaria cancer
5th leading cause of cancer death in women Ovarian cancer
Uterine prolapse is graded in stages 0-4
Stage 0 uterine prolapse Not prolapsed
Stage 1 uterine prolapse over 1cm above hymen
Stage 2 uterine prolapse 1cm above or below hymen
Stage 3 uterine prolapse 1-3cm below hymen
Stage 4 uterine prolapse eversion
Leading cause of infertility PID
Leading cause of ectopic pregnancy PID
Complications of PID Abscess, reoccurrence, dyspareunia
Vaginitis Collective term for infection, inflammation, or change in vaginal flora
Less common than other gynecological cancers Vulvar cancer
HPV vaccine can help prevent Vulvar cancer
Vulvar cancer prognosis Typically good because caught early
Typically secondary to STI Cervicitis
3rd most common gynecological cancer Cervical cancers
Screening/HPV vaccine could prevent 93% of Cervical cancers
HPV+ in 99% of Cervical cancers
Most common location of endometrial tissue Ovary
Endometriosis complications Chronic pain and infertility
Ovarian cyst may contain blood or regular fluid
How PCOS affects ovulation cycle Dont ovulate regularly
PCOS is a diagnosis of exclusion
Most common cause of anovulation infertility PCOS
Complication of ovarian torsion Sepsis
Most common vulvar mass Bartholian gland cyst
If >40 and asymptomatic worries an inflamed bartholian gland may be Vulvar cancer
Most common cause of abnormal discharge BV
Second most common cause of vaginitis Vulvovaginal candidiasis
Complications of vulvovaginal canddiasis Recurrence, Severe, Non-albicans, comorbidities
Causes of abnormal uterine bleeding infection, cervical disorder, endocrine disorder, hematologic disorder
Post menopausal bleeding you are most concerned for Endometrial cancer
Second most common trisomy Trisomy 18
Most common cause of hypogonadism and infertility in med Klinefelter
Most common sex chromosome abnormality Klinefelter
Majority end in fetal demise Turner syndrome
Complications of Prader Willi Osteoporosis, sleep apnea, psychosis
Complication of constipation Hemrroids
5% of all pregnant women develop this Gestational hypertension
Pre-Eclampsia causes arterial spasm in kidneys, brain, liver
Pre-eclampsia is most common in New moms
Severity of eclampsia Emergency
When to deliver w gestational HTN Regular 38w
Incompetent cervix predict at what time 14-16w
Gestational diabetes causes Excessive fetal growth which during birth results in shoulder dystocia
Pre-existing DM causes Excessive fetal growth, miscarriage, or infection
Hydrops Fatalis is a complication of Rh incompatibility
Superimposed preeclampsia complications abruption, mortality, c-section, preterm birth
Placental abruption complications mom DIC, shock, AKI, death
Placental abruption complications fetus growth restrictions, death
Placental abruption complications newborn preterm, small, death
Number one cause of third trimester bleed Placental previa
Dont do digital exam in which case Placental previa
Placental increta into the myometrium
Placental percreta Deep deep
Placental accreta increases risk for hemorrhage
Trophoblastic disease Molar pregnancy where nothing is viable
Most common pregnancy complication Spontaneous abortion
Polyhydramnous associated with fetal malformation and fetal anemia
Oligohydramnous associated with Abnormal developement, or post term pregnancy
Most common TOURCH infection Cytomegalovirus
Complication of cytomegalovirus Hearing loss
Suspect in neonates with fever and meningitis symptoms Herpes Simplex Virus
Hutchinson triad Deaf, cornea, teeth
Complication of conjunctivitis Chemosis
Most common intraocular malignancy of childhood Retinoblastoma
Most common chronic disease of childhood Dental carries
Acute otitis media complications Ruptured TM, chronic effusion, hearing loss, mastoiditis
Complication of acute bacterial pharyngitis Rheumatic fever
Rheumatic fever effects joints, hearts, nodes, erythema, sydenham
Complication of tonsillectomy Post op hemorrhage or hyper nasal speech
Contraindications of tonsillectomy Palate abnormalities, bleeding disorder, acute tonsillectomy
Complications of cleft lip/palate Food coming through nose, otitis media with effusion, failure to thrive because he cannot eat
Most common cause of conductive hearing loss Otitis media w effusion
Complications of rhinosinitus Cellulitis, empyema, brain abscess, osteomyelitis, meningitis
Acute stomatitis examples Canker sore, HSV, thrush, trauma
Most frequently identifiable cause of intellectual disabilities Down syndrome
ADHD may be combined with other psych disorders
Screen for ... with intellectual disorders sleep, feeding, obesity, GI, behavioral, psych
Etiologies of muscular dystrophy Dystrophinopathy, myotonic dystrophy, facioscapulohum, limb-girdle
Duchene Heart asymptomatic until late in disease
Female delayed puberty lowers the risk for breast, ovarian, endometrium
Delayed puberty is associated with lower bone mass, metabolic disease, cardiovascular disease
Mono incubates for 4-8 weeks
Complication of mono Splenomegaly
Turner syndrome complications Coarc of the aorta and bicuspid aorta valve
Epiglottitis is more rare now because H. Flu vaccine
Most common cause of wheezing in infants Acute bronchiolitis
When to screen for bronchiopulm displasia Eval 38w (normal birth time)
Life expectancy for cystic fibrosis 30s
Pectus excavatum Minor other than cosmetic
Acute bronchitis common
This is a complication of other respiratory diagnoses emphysema
Most common chronic ped condition asthma
Highest rate of childhood mortality Bacterial pneumonia
Scoliosis most common cause idiopathic
After 1st UTI pt needs ultrasound to evaluate for vesicouteral reflux
Most common urologic abnormalities in neonates Vesicoureteral reflux
Complications of cryptochordism Infertility, neoplasm, torsion, hernia
Most common kiddo surgery is for appendicitis
Appendix perforation happens ...h after onset 36
50% of these patients need transplant or dialysis by 20s Autosomal recessive polycystic kidney disease
Pulm complications of this are what lead to death Autosomal recessive polycystic kidney disease
Acute interstitial nephritis Fever, eosinophilia, acute renal insufficiency, rash
Most common cause of nephritic syndrome Glomerulonephritis from strep
Complication of pyloric stenosis Metabolic alkalosis
Complication of celiac Malabsorption and malnutrition
Most common cause of obstruction less than 2 Intussussception
Most common cause of intussussception idiopathic
Botulism symptoms in older diplopia, dysarthria, dysphagia
Most common congenital abnormality of GI tract Meckel diverticulum
Complication of developmental displasia Avascular necrosis
RF for developmental dysplasia Female, first born, breech
Most common cause of acute hip pain in kiddos Transient monoarticular synovitis
Transient monoarticular synovitis is a diagnosis of exclusion
Knee pain requires eval of the hips
Genu valgum normal until about 4yr
Genu varum Bow legged
Genu valgum knocked knees
Second most common peds spinal deformity Kyphosis
Growing pains is a diagnosis of exclusion
DDX for growing pains Infection, metabolic, tumor, trauma
Most common salter harris fracture 2
Scary salter harris fractures 3-5
Complication of supracondylar fracture Neurovascular compromise
Most common cause of functional constipation Purposefully holding
If you see coin face on AP its in the esophagus
Most common location of atrial septal defect Near foramen ovale
Types of ventricular septal defect Perimembranous, supracristal, inlet, muscular
Most common ventricular septal defect Perimembranous
Most common kiddo heart condition Ventricular septal defect
Coarction of the aorta Doesn't get blood to lower body efficiently
Types of atrioventricular canal defect Complete, intermediate, transitional, partial
Truncus arteriosus One great vessel leaving the heart
Most common cyanotic defect in newborns Transposition
Most common cyanotic defect Tetralogy of fallot
Most common cause of heath from cardiac in the first month of life Hypoplastic left heart syndrome
Multidrug resistance Pathogens that are resistant to 1+ antimicrobial agents
Key factors in prevention of antibiotic resistance Antibiotic stewardship, universal precautions, active surveillance, personal/environmental hygiene
Healthcare associated infections CAUTI, HCAP, vascular catheter, surgical site infxn, C. diff
Most expensive HCA infextion Central line
CAUTI rx abx based on culture
Most effective rx for CAUTI prevention
If a CAUTI is asympomatic dont rx
Bugs for CAUTI #1 E. Coli, #2 Candidia, #3 Enterococcus
Most common HCA infection CAUTI
Complication of CAUTI mortality
Second most common HCA infection HCAP
HCAP rx Culture driven abx- Antipseudomonal cephalosporin
Best HCAP rx prevention
Bugs causing HCAP #1 Pseudomonas, #2 MRSA
CLABI rx Line out ASAP and send to lab for pathology, Abx based on culture
Top cause of CLABSI Hub contamination
Riskiest place for IV cath due to infx Femoral
CLABSI causes #1 Hub contamination, contamination of fluid running through, skin organisms, contaminated device prior to insertion
Bugs causing CLABSI #1 Staph, at femoral Enterococcus and E. Coli
CLABSI grows staph coag negative treat with Vancomycin for 1 week
CLABSI grows stap treat with Vancomycin for 2 weeks and TEE
CLABSI grows gram negative rod treat with Beta lactam for two weeks
CLABSI grows candida treat with Fluconazole 2w
Complicated CLABSI rx 4-6weeks of abx
Surgical site infection bugs Skin- SSE
Surgical site infection rx <5cm open and drain
Surgical site infection rx >5cm open and abx
Abx for small surgical site infection Cephalosporin or combo
Stress incontinence symptoms Leakage with laugh, exercise, cough, incontinence, no dysuria
Urge incontinence symptoms Frequency, urge, nocturia
Overactive bladder symptoms Frequency, urge, nocturia
Overflow bladder symptoms Spontaneous or continuous leak
Stress incontinence rx Kegals and timed void
Urge incontinence rx Antimuscarinic + B3 adrenergic, kegals
Overflow incontinence rx Bladder training, intermittent cath, alpha adrenergic antagonist
BPH rx Alpha adrenergic antagonist
Insomnia Difficulty falling or staying asleep, waking up early, associated with daytime impairment
Consequences of insomnia Lower health related quality of life, increased medication use, cognitive decline, greater health care utilization
Common primary sleep disorders Insomnia, obstructive sleep apnea, restless leg syndrome, periodic leg movements in sleep
Insomnia screening are you satisfied with your sleep, does sleep or fatigue interfere with daytime activities, do bed partners complain of snoring/interrupted breathing/or excessive movements
Meds that impact sleep Meds that cause lighter, shorter/fragmented sleep, nightmares, nocturia, sedation, stimulation
Meds that cause lighter, shorter/fragmented sleep Alcohol, sedatives, cholinesterase inhibitors
Meds that cause nightmares Antidepressants, anti-Parkinson, anti-HTN, cholinesterase inhibitors
Meds that cause nocturia Diuretics
Meds that cause sedation Antidepressants, clonidine, phenytoin, sedatives
Meds that are stimulants that keep you from sleeping Bronchodilators, caffeine, nicotine, corticosteroids, sympathomimetics, antidepressants
Rx to improve sleep #1 Non-pharm, #2 meds
Non-pharm things to do for sleep Stimulus control, sleep restriction, cognitive intervention, relaxation, CBT, light exposure
Pharm things to do for sleep smallest shortest duration, to discontinue med do behavior changes and taper
SSRI/benzos help with anxiety
Meds for insomnia Zolpidem, Zalepon suvorexant
Polypharmacy Therapeutic duplication or medical insufficiency through 5+ meds
Meds we worry about with polypharmacy Benzos, opioids, anticholinergic, sedatives/sleep, muscle relaxants, tricyclic antidepressants, antipsychotic
Leading cause of death from injury >65 Complications from falls
Falls are associated with Increased use of medical services, decline in functional status, nursing home placement, increased mortality
Fall screening Have you fallen in the last year, do you feel unsteady when walking or standing, do you fear falling
Test for fall Timed Get Up and Go
Things to exclude with falls syncope or seizure
Meds to worry about with falls drugs that cause bradycardia, drugs that cause orthostatic hypotension, CNS active meds, general meds
Meds that can cause bradycardia Cholinesterase inhibitors, antiarrhythmics, beta blockers
Meds that can cause orthostatic hypotension Antihypertensive meds, nitrates, SGLT2, diuretics, antipsychotic, some antidepressants
CNS active meds Benzos, antidepressants, antipsychotics, anticonvulsants
General meds that can cause falls Anticholinergics, antihistamines, insulin and oral hypoglycemics, narcotics, sedative hypnotics
Incontinence red flags Sudden onset, pelvic or abd pain, hematuria, dysuria, severe straining, inability to void
A common but NOT normal part of aging incontinence
Incontinence screening Do you have trouble with your bladder, do you ever loose urine when you do not want to, do you ever wear pads to protect yourself in case you loose urine
Meds that may impact incontinence sedative/reduced mobility, urgency/frequency, sensory, sphincter tone, edema, cough, incomplete emptying, bladder irritants
When to refer incontinence to urology Hx lower urinary surgery or radiation, recurrent symptomatic UTI, marked pelvic prolapse, suspected prostate cancer, sterile hematuria
Geriatrics mindset change from acute care to healthy aging
Functional geriatric disabilities Independent living, self-care, ambulatory, cognitive, vision, hearing
Challenges of geriatric care difficult to develop age-related guidelines for diagnoses and rx, multiple comorbidities, >50% of 80yr have 3+ chronic conditions, majority have some type of cognitive impairments, reduced social support, limited finances, functional disabilities
Geriatric syndromes Delirium, functional decline, new incontinence, pressure injury, fall
Cytomegalovirus rx Grancyclovir
Herpes Simplex virus rx Acyclovir
HSV 1 Oral herpes
HSV 2 Genial herpes
Herpes bugs HSV 1, HSV 2, CMV, EBV, HHV 6, 7 ,8
Toxoplasmosis rx Pyrimethamine w sulfadzine
Rhinovirus rx supportive
Croup rx mild Humidity
Croup rx moderate Dexamethasone
Croup rx severe Steroids, O2, epi inhaler, admit
Parovirus B19- Fifths
Adenovirus symptoms Conjunctivitis, diarrhea, cold symptoms
Poxvirus examples Cow pox, monkey pox, small pox
Picornavrus GI or Respiratory
Diptheria rx Azithromycin and penicillin
Diptheria bug Cornebacterium diptheria
Rheumatic fever bug Group A strep
Bacterial meningitis bug N. Meningitidus
Bacterial meningitis rx Penicillin
Acute otitis media rx Amoxicillin
Acute otitis media bug Strep pneumo, Staph, M Cat, H flu
Acute bacterial pharyngitis rx Amoxicillin or Penicillin
Acute bacterial pharyngitis bugs Group A strep
Rhinosinusitis rx Amoxicillin
Epiglottitis bug H flu
Epiglottitis rx Ceftriaxone and Dexamethasone
Primary tuberculosis bug Mycobacterium tuberculosis
Cellulitis rx Cephalexin
Cellulitis bug Staph
MRSA rx #1 Trimethoprim-sulfamethoxazole or Clindamycin, #2 Doxy
Tetanus rx #1 Wound debridement and metronidazole, #2 Neutralize toxin, #3 Supportive care, #4 Tdap
Tetanus bug Clostridium tetani
Erysipelas bug Beta hemolytic Strep A
Erysipelas rx Amoxicillin or Penicillin
Hidranitus supportiva rx Tetracycline
Do not use these antibiotics when pregnant Antimetabolites
Why we do not use antimetabolites in pregnancy They inhibit folic acid metabolism
Chlamydia trachomatis rx Doxycycline
Bacterial vaginosis rx Metronidazole
PID rx Metronidazole, Doxy, and Ceftriaxone
Gonorrhea rx Ceftriaxone
Treponema pallidum rx Penicillin G
Trichomonas rx Metronidazole both partners
Lyme bug Borella Burgdorferi
Rocky Mountain Spotted fever bug Rickettsia Rickettsii
Bartonella bug Bartonella henselae
Botulism bug Clostridium botulism
Botulism rx Botulism antitoxin
Salmonellosis bug Non-typhoidal salmonella
Salmonellosis rx Not abx
Shigellosis rx Not abx
Campylobacter jejuni rx No abx
Clostridiodes difficle abx Oral vanc or ...
Cholera bug Vibrio cholera
Rashes that have a fever and affect oral mucosa Hand Foot and Mouth, Herpangina, HSV 1, Herpatic Gingivostomatitis, Erythema Mulitforme major
Rash that has a fever and rash on the face 5ths
Rash that has a fever and goes head down Measles and Rubella
Rash that has a fever and honey crust Impetigo
Rash that comes 24-48 hours after a fever Roseola
Bullae rash with fever Staph scalded skin
Sandpaper rash with fever Scarlet fever
Raised rash with fever and pain out of proportion typically on legs Erysipelas
Erythematous rash with fever typically on legs Cellulitis
Petechiae rash +/- neuro, and fever Meningococcus
5 days of fever and rash Kawasaki
Maculopapular rash 7-10 d after starting medication may or may not have fever Drug rxn
Harold patch rash with fever Pityriasis Rosea
Papular rash on palms soles and face with fever Gianotti Crosti
Target lesion rash on palms and soles with fever Erythema Multiforme Minor
Mucocutaneous rash on hands with fever Herpetic Whitlow
Annular rash central is white everywhere without fever Tinea corporis
Pearly waxy papule rash everywhere without fever Molluscum
Cauliflower rash everywhere without fever Verrucae
Baby rash on face and trunk without fever Neonatal acne
Baby booty rash without fever Diaper dermatitis
Rash where feet peel without fever Tinea Pedis
Annular patch on scalp without fever Tinea capitis
Greasy flakes on scalp without fever Seborrheic dermatitis
Hand Foot and Mouth Rx Self-resolving supportive care
Herpangina rx Self-resolving supportive care
Gianotti Crosti rx Self-resolving supportive care
Measles rx Self-resolving but MMR vaccine can prevent
Rubella rx Self-resolving but MMR vaccine can prevent
Erythema infectiosum rx Self-resolving supportive care
HSV 1 rx
Herpetic whitlow rx Self-resolving, supportive, or acyclovir
Eczema herpeticum rx
Varicella rx Vaccine
Roseola infantum rx Self-resolving supportive care
Tinea corporis rx Antifungals
Tinea capitis rx Oral grisoful or ketoconazole shampoo
Tinea pedis rx Antifungals
Diaper dermatitis rx Kep area clean and dry, treat yeast with nystatin
Staph scalded skin rx Fluids, abx, skin care, ADMIT
Scarlet fever rx Amoxicillin
Erysipelas rx IV penicillin, ADMIT
Staph cellulitis rx Oral or IV abx
Impetigo rx Topical abx if there is a small area or oral abx if diffuse
Meningococcus rx Penicillin
Kawasaki rx IVIg, hgh dose aspirin
Drug rxn rx stop med
Henoch Schoenlein purpura rx Steroids for joints and GI, NSAIDS for pain
Neonatal acne rx self-resolving
Seborrheic dermatitis rx self-resolving, selenium sulfide shampoo, or mineral oil
Eczema rx Moisturize, remove triggers, steroids if needed
Molluscum rx Self-limited can be removed
Verrucae rx Self-limited can be removed
Pityriasis rosea rx Self-resolve 8-10w
Scabies rx Permethrin cream, wash all things on hot
Lice rx Permethrin, sklice, Nit removal, wash all things on hot
Geriatric syndromes Common health conditions in older adults that do not fit into distinct organ-based disease categories and often have multifactorial causes
Geriatric disorders that affect the mind Dementia, Delirium, Depression
Geriatric disorders that affect mobility Amount of mobility, impaired gait and balance, fall injury
Geriatric disorders that affect medications Polypharmacy, optimal/safe prescribing, adverse medication effects and medication burden
Impact of elder abuse Physical injury/pain, worsening chronic conditions, dehydration, pressure ulcers, emotional distress, loss of income and savings
Abandonment signs Evidence patient is left alone unsafely, patient is dropped off and needs a responsible party
Physical abuse signs Anxiety, nervousness, withdraw, bruising, wounds in unusual locations, repeated ED visits, repeated falls, signs of SA
Exploitation signs Evidence of misuse of patients assets, change in ability of patient to account for money and property or pay for essential care, reports of demands unreasonable amounts of money or goods in exchange for caregiving, unexplained loss of checks, refills meds
Neglect signs Contractures, dehydration, depression, fecal impaction, malnutrition, inappropriate use of meds, pressure ulcers
Psychological abuse signs Observed impatience, irritability or demeaning behavior
Basic tenets of geriatric care Aggressive primary care, patient centered, technology to track, teamwork, efficient, slow decline
Pathogenesis of HTN Increased arterial stiffness, dysfunction of the endothelium, fibrosis of glomerulosclerosis and interstitial
Goal of systolic BP >65 130
Nonpharm treatment of HTN Decrease Na, Decrease alcohol, Exercise, stop smoking, loose weight
Meds that increase BP NSAIDS, venlafaxine, steroids
Number one pharm treatment for HTN Chlothalidone
Med classes to treat HTN thiazide, calcium channel blockers, (dihydropuridine and nondyhydropurdine), ACE, ARB, BB
Not recommended to treat HTN in geriatrics Potassium sparing diuretic, alpha blockers, alpha adrenergic receptors
CAD nonpharm treatment Lifestyle- smoking cessation, BP control, lipid management, diabetes management, weigh and diet management, physical activity
Pharm for CAD Aspirin, Nitrates, BB, ACE/ARB, Statins
Other than the big two what are the lung related diseases that impact geriatrics Interstitial disease and pulmonary hypertension
Asthma diagnoses <12 is likely from atopy
Asthma diagnosis >40 is likely from smoking and obesity
Grade 1: Mild COPD FEV >80
Grade 2: Moderate COPD FEV 50-80
Grade 3: Severe COPD FEV 30-50
Grade 4: Very Severe COPD FEV <30
treatment for COPD SABD, LABA/LAMA, LABA+LAMA, LABA+LAMA+ICS, Biologics
What may impair patient's self treatment of diabetes Cognitive, visual, or functional impairment
Diabetes pharmalogical rx #1 Metformin, #2 SGLT-2, #3 DPP-4, #4 Insulin
Diabetic rx not preferred in geriatrics Thiazolidines, Sulfonurea, GLP1
Pathophys of osteoarthritis Changes to cartilage architecture, changes to subchondral bone, synovitis and synovial hypertrophy
Systemic diseases associated with developing osteoarthritis RA, SLE, hyperparathyroidism, gout, diabetes, bone dsplasia
osteoarthritis affects which joints Knees, hips, hands, back
Osteoarthritis is a Clinical diagnosis
Challenges to caring for geriatric patients No age-related guidelines, multiple comorbidities, 3+ chronic conditions, cognitive impairment, reduced social support, limited finances, functional disabilities
Advanced directive gives you the right to make any health care decisions in advance; ensures that you, your loved ones, and your healthcare team honor your wishes
Leading cause of fatal and nonfatal injuries among people >65 Falls
Intrinsic fall risk factors Cognitive impairment, functional limitations, medications
Extrinsic fall risk factors Footwear or foot problems, home hazards, improper use of assistive devices, eyeglass use, substance use
Easier quick fixes for fall risk factors extrinsic risk factors
Polypharmacy Multiple meds being taken for the same problem, higher risk if >5meds
Prescribing cascade older adults often experience drug side effects> AE from drugs>new drug to deal with AE>possible new side effects
Deprescribing planed or supervised process of dose reduction or stopping meds that may cause harm or no longer providing benefit
Dementia warning signs trouble remembering, "poor historian", cant follow instructions, getting lost, problems with self care, unexplained weight loss
DSM5 criteria for Dementia Evidence of decline in memory and learning as well as one other cognitive domain, progressive gradual decline in cognition without extended plateaus, no mixed etiology
Meds for dementia Acetylcholinesterase inhibitors and NMDA antagonists
Lag to benefit Time between the preventive intervention to the time when improved health outcomes are seen
estimating prognosis Prognostic indices based on clinical situation
Geriatric syndromes Common health conditions in older adults that do not fit into distinct organ-based disease categories and often have multifactorial causes
Geriatric Mind Mentation, dementia, delirium, depression
Geriatric Mobility Amount of mobility, function, impaired gait and balance, fall injury prevention
Geriatric medication concerns Polypharmacy, deprescribing, optimal/safe prescribing, adverse medication effects and medication burden
What matters most to geriatrics Each individual's own meaningful health outcome goals and care preferences
Fall An event that results in a person coming to rest inadvertently on the ground, floor, or other lower level without known loss of conciousness
Falls are associated with Increased use of medical services, decline in functional status, nursing home placement, increased mortality
Circumstances of fall Frequency, location, activity at time of fall, trip/slip, environmental hazard
Symptoms associates with falls Dizzy, cardiovascular, focal neural, volume depleted
UTI rx antibiotics, do not treat asymptomatic
Atrophic vaginitis/urethritis rx topical estrogen
Stool impaction affecting bladder rx Fecal disimpassion, appropriate use of bowel regimen
Metabolic reaction affecting bladder rx Treat underlying
Volume overload affecting urine production rx Compression socks
Venous insufficiency with edema effecting urine rx leg elevation and sodium restriction
Psych conditions associated with sleep disturbance adjustment disorders, anxiety, bereavement, depression, PTSD
Cardiopulm conditions associated with sleep disturbance cough, dyspnea, apneas, palpitations, chest paiin
Neurologic symptoms associated with sleep disturbance Pain, paresthesia, Parkinson, RLS, seizure, stroke
Abandonment Evidence patient is left alone, unsafely, patient is dropped off with no one to care
Physical abuse Anxiety, nervousness, withdraw, bruising, wounds in unusual places, repeated ED visits, repeated falls, signs of sexual abusee
Exploitation Evidence of missuses of patients assets, change in ability of patient to account for money and property or pay for essential care
Neglect Contractures, dehydration, depression, diarrhea, fecal impaction, malnutrition, inappropriate use of medications, poor hygiene, pressure ulcers, repeated falls, repeated hospital admission, urine burns
Psychological abuse Observed impatience, irritability, demeaning behavior, anxiety, fearfulness, ambivalence or anger shown by patient about caregiver
Aggressive primary care for geriatrics include Proactive monitoring and early intervention
Pathogenesis of hypertension Increased arterial stiffness due to decreased elastin, dysfunctional endothelium, renal glomerulosclerosis and interstitial fibrosis
Number one med for HTN rx geriatrics Chlorthalidone
Meds not to take for HTN geriatrics Triamterene, Terazosin, Doxazosin, Prazosin, Clonidine
Gold standard coronary artery disease diagnostic coronary angiography
Lung-related diseases with lower prevalence in geriatrics interstitial disease and pulmonary HTN
<12 asthma cause atopy
>40 asthma cause smoking and obesity
Curative cancer involves surgery, radiation, and or chemo, all poorly tolerated in geriatrics
Palliative cancer treatment Preferred in patients w advanced-stage cancer w low probability of cure, shorter life span, comorbidities that might limit more aggressive rx, or patient choice
Toxoplasmosis rx Premethamine w sulfadaziine
CMV rx Grancyclovir
CMV transmission Cross placenta to baby, get from toddler waste, also concerned for in immunocompromised
CMV symptoms blueberry rash, microcephaly, fever, mental retardation, developmental delays
HSV-1 rx Acyclovir
HSV-2 rx Acyclovir
Rhinovirus trasmission Secretions
Rhinovirus is part of which family Picornavirus
Croup rx mild humidity
Croup rx moderate dexamethasone
Croup rx severe steroids, O2, nebulized epi
Fifth type of genome Single stranded DNA
Fifths targets what Erythropoietin progenitor cells
Fifths S+S Transient aplastic crisis, anemia, may have cold symptoms, slapped cheeks
Complication of Fifths Hydrops fatalis
Adenovirus type of genome Non-enveloped DNA
Adenovirus in immunocompromised Disseminated infxn
Pox viruses smallpox, cow pox, monkey pox, moluscum
Poxvirus rx None
Pox virus transmission Spread by direct and indirect contact
Polio is in what family Picornavirus
Cocksackie is in what family Picornavirus
Rhino virus is in what family Picornavirus
Enterovirus is in what family Picornavirus
Varicella/Zoster transmits via secretions and skin
Varicella/Zoster lays dormant where Dorsal root ganglia
Epstein Bar Viruses long term complications B lymphoma, or Burkette lymphoma
Diphtheria bug Corynebacterium diphtheria
Corynebacterium diphtheria bug classification Gram + rod
Diphtheria rx Azithromycin or penicillin
Pathophys of diphtheria Exotoxin to skin and respiratory, causes cell death
Diphtheria symptoms Gray pseudomembranous, malaise, fever, lymphadenopathy, sore throat
Rheumatic fever rx IV penicillin
Rheumatic fever can affect heart, skin, and joints
Jones criteria Two major or one major and two minor criteria
Acute otitis media rx Amoxicillin
Rhinosinusitis rx Amoxicillin
Epiglottitis rx Ceftriaxone and Dexamethasone
Most common bugs for skin and soft tissue Strep pyrogens and Staph
Cellulitis rx Cephalexin
HA-MRSA transmission hands and surfaces
CA-MRSA transmission person or object
Tetanus bug Clostridium tetani
Clostridium tetani classification Anaerobic, spore forming, gram positive rod
Pathophys of Tetanus Motor neurons are continuously firing bc of tetanospasm (toxin)
Erysipelas rx IV penicillin or amoxacillin
Impetigo bug staph
Salmonella class Gram negative rod, aerobic
Salmonella enters what part of GI small intestine and colon
Shigella class Gram negative rod, anaerobe
Complications of shigella seizures or toxic encephalopathy
Where does shigella enter the GI tract Colon at recto sigmoid
Campylobacter invades what part of GI tract small intestine to rectum
Shigella stool Bloody and mucus
C diff bug class Gram positive bacilli, anaerobic, spores
Cholera bug Vibrio cholerae
Vibrio cholerae bug class Gram negative bacilli
Cholera transmission Contaminated water and food
Chlamydia bug class Intracellular oblique
Chlamydia discharge white/yellow
BV discharge clear/gray
Gonorrhea discharge purulent
Trich discharge Green froth
Syphilis transmission STI or placenta
Burgdifore class spirochete
Lyme is endemic to where Northeast and midatlantic
Rocky Mountain Spotted Fever bug Rickettsia Rickettsi
Rickettsia rickettsi class Gram negative oblique intracellular
Rickettsia rickettsi transmit via Dog tick and wood tick
Rickettsia rickettsi symptoms Hemorrhage in skin, intestines, pancreases, liver, skeletal muscle, kidneys
Rickettsia rickettsi is endemic to where Southeast and Central US
Bartonella H stain via silver stain
Bartonella bug class Gram negative bacillus
Botulism bug Clostridium botulism
Clostridium botulism class Gram positive rod
Botulism leads to cranial nerve palsy, descending paralysis, but no altered mental status
Surgical site most common bugs Skin flora
Surgical site infection rx <5cm open and drain
Surgical site infection rx >5cm open and abx (cefalosporin)
Systemic surgical site infection rx reopen, debried, abx
Rx for C. Diff #1 Fidaxomycin or oral Vanc, #2 oral metronidazole
CAUTI most affective rx prevention
CAUTI rx asymptomatic do not treat
CAUTI bugs #1 E. coli, #2 Candida, #3 Enterococcus
Most common HCA infection CAUTI
HCAP bugs #1 Pseudomonas, #2 MRSA
Staph coag rx in CLABSI Vanc for 1w
Staph rx in CLABSI Vanc 2w with TEE
Gram negative rods rx in CLABSI Beta lactams
Complicated CLABSI rx timline 4-6w
#1 cause of CALBSI hub contamination
CLABSI bugs Skin flora- STAPH, or femoral GI
Cryptosporidium symptoms watery diarrhea
Cryptosporidium comes from Feces
Cryptosporidium rf AIDS
Cryptosporidium rx Nitrazoxinide
PJP gold standard ds PCR or stain
PJP rx ART (AIDS), Bactrim, Steroids if respiratory compromised
If CD4 > 200 and respiratory symptoms likely community acquired pneumonia
Histo symptoms Respiratory and flu like
Histo CD4 count <150
Histo rx Intraconazole
Do you prophylaxis hisot yes- CD4 <150
When to rx histo Symptomatic >1M or immunocompromised
Histo RF Ohio river valley and Mississippi
Toxoplasmosis symptoms White retinal lesion and pigmented scars
Toxoplasmosis diagnostic studies MRI most sensitive- Ring enhancing lesions
Definitive diagnosis for toxoplasmosis Brain biopsy
Toxoplasmosis rx Pyrimethamine and sulfadiazine with fulinic acid
If you are pregnant with toxoplasmosis add spiramy to your rx
Kaposi sarcoma symptoms widespread rash, including mucosa
Kaposi sarcoma rx ART (AIDS) and Chemo
Diagnostic studies for kaposi clinical diagnosis
MAC symptoms pulmonary, fever, night sweats, weight loss
MAC diagnostics Bronchial lavage, chest CT, blood culture
MAC rx 12m Clarithomycin and Ethambutol
MAC facts no latent infection, may mimic hematologic malignancy
Candida likes blood and mucosa
Candida diagnostics KOH budding hyphae
Candida rx topical azole or nystatin
Invasive candida rx Amphotericin, Fluconazole, Echinocandia
Most common type of candidia Candida albicans
Coccidio symptoms flu like, back ache, headache
Coccidio diagnostics CXR - patchy nodular lobe
Coccidio is found where in the US South
Coccidio rx Itraconazole or fluconazole 6m
Do you propholax for coccdio no
Fungal coccidio meningitis rx for life
Constipation rx mild bulk forming, senna, poly glycol
Constipation rx sever suppository, enema, mag citrate
Death rattle rx Atropine eye drops or scopolamine patch
What is the death rattle from extra secretions
When do you hear the death rattle Last 48 hours of life
Anxiety medication for geriatrics Lorazepam, therapy
Mild pain rx geriatrics Tylenol and NSAIDS
Moderate pain rx geriatrics Mild opioids and Non opioids
Severe pain rx geratrics Opioids
How to schedule pain meds every 4-6 hours with break through
Most common symptoms patients experience Pain
Breathless rx O2, circulation, change position, morphine
Nausea rx Zofran, prochioperaz, haloperidol
Asthma rx LAMA/LABA
Do not use this in geriatric asthma patients SABA
Difference between young v old with asthma 4x increase in geriatric mortality
Diabetes geriatric A1C goal 7-7.5
Diabetes rx #1 Metformin, #2 SGLT-2, #3 DPP, #4 Insulin
Do not use as diabetes rx in geriatrics Sulfonurea or thiazolid
do not use as HTN rx in geriatrics Clonodine
Goal bp for geriatrics 130/80
Anemia in women Hgb <12
Anemia in men Hgb <13
Overflow incontinence symptom spontaneous or continuous release
Stress incontinence rx kegals and times void
Overactive/urge rx Antimuscarinic
Overflow rx Alpha adrenergics
Down syndrome diagnostics Nuchal translucency
Fetal alcohol syndrome presentation wide eyes, flat filtrum, thin upper lip, microcephally
Cerebral palsey RF Birth or pregnancy brain trauma
ADHD symptoms Inattention, hyperactivity, and impulsive
How to assess ADHD vanderbuilt assessment scale
Duche Muscular dystrophy symptoms Heart and gowers sign with standing
MCC of peds conductive hearing loss Otitis media wit effusion
Acute viral rhinitis symptoms <10d common cold
Bacterial rhinosinusitis >10d common cold
Acute viral pharyngitis bug Adenovirus
Negative red reflex Leukocoria
Retinoblastoma mutation RB1
MC cause of pediatric ocular cancer Retinoblastoma
Bugs of Acute otitis externa Staph or pseudomonas
Dont do a tonsillectomy if Palate abnormality, bleeding disorder, tonsilitis
Transposition aorta and pulmonic trunk did not twist- aorta goes to left atrium
Tricuspid atresia Tricuspid valve fails to form
Tetralogy of fallot Tet spells and pulmonic stenosis murmor
Most common cyanotic defect Tetralogy of fallot
Most common cause of cardiac death in the first month Hypoplastic left heart syndrome
Most common defect of the heart VSD
Machine like murmor Patent ductus arteriosis
Coin face in AP Coin in esophagus
Coin side in AP Coin in trachea
Celiac test tTG and total serum IgA
Intussusception stool Currant jelly stool
Most common cause of bowel obstruction <2 Intussusception
Most common congenital abnormality of the GI tract Meckels diverticulum
Acute interstitial nephritis cast WBC
Glomerulonephritis post strep cast RBC
Most common cause of nephritis syndrome Glomerulonephritis post strep
Complication of sigella HUS
Scoliosis angle <20 watch
Scoliosis angle 20-50 brace
Scoliosis angle >50 surgery
Pulmonary agenisis failure for one of the lungs to form
Bronchio displasia how much O2 baby needs at 36 weeks from conception
Most cancer dx are after the age of 65
Malaria fever pattern fever every 3/4 days
Undulant fever in brucellosis pattern fever in the evening, gone by morning
Lyme fever pattern Long week fever with a long week of remission
Hodgkin fever pattern Week long HIGH fever with week long remissions
Two fever spikes a day point to Still, Malaria, or typhoid
Neonate fever bugs #1 E. coli, Group B strep, Listeria, Neonatal HSV
When peds fever needs further workup Over 3 days or above 102.2
Created by: kendallmk
 

 



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