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Biochem Chapter 11

QuestionAnswer
Building a nucleic acid (3) 1. Nitrogenous base 2. Pentose Sugar 3. Phosphate
RNA Ribose
DNA Deoxyribose
DNA to DNA 5'AGTCGATA3' 3'TCAGCTAT5'
DNA to mRNA 3'ACTGGCAA5' 5'UGACCGUU3'
DNA strands are Double and anti parellel
Transcription DNA->mRNA
Translation mRNA-> Polypeptide
When finding names on the wheel, make sure it is mRNA ( it needs uracils to work)
How often are mutations in DNA a coding problem? 2% of the time RARE
Is LEU->ILE a likely or unlikely impact? Unlikely Because they are both Non Polars
Is THR->GLY a likely or unlikely impact? Likely Because THR is Polar and GLY is Non Polar THEY ARE NOT INTERCHANGEABLE
Frameshift mutations Insertion: One or more bases are added to the DNA sequence. Deletion: One or more bases are removed from the DNA sequence.
Both Insertion and Deletion.... Both insertions and deletions can shift the "reading frame" of the genetic code, leading to a completely different amino acid sequence downstream of the mutation.
Silent mutation The change in the base does not alter the amino acid sequence
Sources of mutations -Random -Mutagens (UV light, Radiation, Nitrites)
Created by: liladdoyle
 

 



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