click below
click below
Normal Size Small Size show me how
Pharm Exam 3
| Term | Definition |
|---|---|
| ACE inhibitors MOA | -End n -pril -Inhibit RAAS (less vasodilation and sodium/water retention) -First line treatment for heart failure |
| ACE inhibiters adverse effects | -Hypotension -Hypokalemia (caution if taking potassium-sparing diuretics) -Cough, angioedema -Fetal harm in 2nd and 3rd trimester |
| Beta blockers MOA | -End in -lol -Block epinephrine and norepinephrine receptors -Decreased HR and contractility --> reduced CO |
| Beta blockers used for HF | -Metoprolol succinate (long-acting) -Carvedilol -Bisopropolol |
| Beta blockers adverse effects | -Fluid retention (worsens HF) -Hypotension, bradycardia -Fatigue |
| Aldosterone antagonists (spironolactone) MOA | -Block aldosterone receptors in heart and blood vessels -Reduces water and sodium retention -Preserves potassium |
| Aldosterone antagonists adverse effects | -Hyperkalemia -Gynecomastia (enlarged breasts in men) |