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patho exam 3

eye and hearing disorders

QuestionAnswer
structures within ear hear and interpret sounds provide information about position and movement of head in space
receptors within eye shapes and colors conveyed in light energy
impairments alter information available to cortex to process disease, aging, medications, environmental factors, genetics
disorders of hearing, balance, vision have a negative effect on overall quality of life
children born with hearing or vision deficits developmental, communication, mobility delays
adults with vision or hearing loss problems with mobility, nutrition, stress, coping, mood, affect increased susceptibility to environmental issues
hearing process sound waves transformed into neural impulses pitch, loudness, timing preserved at each step, allowing brain to perceive sound accurately
pathologies of the auditory system disrupt normal sound transmission
types of hearing loss sensorineural - makes sense of sounds conductive - conducts vibrations of sound waves mixed
auricle (pinna) collects sound pressure waves; directs them into external auditory canal generates cues about timing and intensity of sounds to localize
ossicles malleus (largest); incus; stapes attached oval window, which leads to fluid filled inner ear
external acoustic meatus ends at tympanic membrane, or eardrum
external acoustic meatus is lined with hairs and glands that secrete cerumen to protect the rest of hearing system from dust/debris
tympanic membrane sound receptor and transmitter, vibrations transmitted to ossicles
neural signal pathway along auditory portion of the vestibulocochlear nerve, exits cochlea via internal auditory canal, travels through multiple nuclei in brainstem, proceeds to thalamus, reaches primary auditory cortex, located in temporal lobe
inner ear: bony labyrinth consists of cochlea (hearing), the vestibule (acceleration) and the three semicircular canals (balance)
inner ear: bony labyrinth system of canals in temporal bone fluid filled membranous labyrinth
inner ear: cochlea canals where waves of sounds make sense, scala vestibuli, scala media, scala tympani
inner ear: cochlea are filled with perilymph (similar to CSF)
inner ear: cochlea = pressure windows
kinetic labyrinth semicircular ducts in semicircular canals - anterior, posterior, lateral
static labyrinth utricle in vestibule saccule in vestibule
peripheral balance system: possible effects of loss of peripheral balance function vertigo feelings of unsteadiness visual blurring hearing sensitivity
peripheral balance system: causes of balance disruption certain diseases and conditions central vestibular disorders some medications
conductive hearing loss disorders sound unable to travel normally to inner ear reflects audibility problem
types of conductive hearing loss outer ear disorders otitis media - most common of middle ear otosclerosis - disorder of middle ear
outer ear disorders are highly treatable (most)
outer ear disorders typically do not involve hearing loss except congenital outer ear malformations
some common outer ear disorders cerumen impaction, collapsed ear canal, external otitis, stenosis of ear canal, microtia or anotia
otitis media (OM) is the inflammation of middle ear space
otitis media (OM) associated with eustachian tube dysfunction because exudate blocks eustachian and nasal tube which blocks the membrane and causes a respiratory problem
otitis media (OM) CMs coldlike symptoms and/or upper respiratory problems
acute otitis media (OM) inflammation of middle ear with acute onset moderate to severe bulging of TM and middle ear effusion
acute otitis media (OM) complications rupture TM conductive hearing loss (temporary)
acute otitis media (OM) treatment antibiotics
reccurent otitis media (OM) Three or more episodes of AOM in 6 months or four or more episodes in 12 months
factors that increase risk of reccurence of reccurent otitis media (OM) male gender, passive exposure to smoking, winter season
chronic otitis media infection longer than six weeks with persistent effusion in middle ear space mild to moderate conductive hearing loss (if not treated)
chronic otitis media treatment topical antibiotics and/or steroids frequent cleaning of ear canal (tube to drain exudate from canal)
severe cases of chronic otitis media treatment surgical intervention and/or systemic antibiotics ventilation/pressure equalization (PE) tubes
ostosclerosis is the abnormal bone growth in middle ear space which blocks sounds and the ossicle enlarged
associated hearing loss Bilateral - lose hearing in both ears Slowly progressive Conductive - can be mixed if otic capsule is involved
etiology and pathogenesis of ostosclerosis Alternating bone resorption and formation Genetic component as autosomal dominant Viral factors Autoimmune system disorders
diagnosis of ostosclerosis Patient history Otoscopy Audiologic results Radiologic results
treatment of ostosclerosis Annual hearing tests to monitor hearing loss Surgical procedures - diminish size of ossicles Hearing aids Fluoride, calcium, vitamin D - nutritional components
presbycusis is hearing loss due to aging
presbycusis is the most common form of hearing loss
four types of presbycusis Sensory presbycusis Neural presbycusis Metabolic, or strial, presbycusis Mechanical, or cochlear conductive, presbycusis
Sensory presbycusis problem with cochlea
Neural presbycusis problem with CNs
Mechanical, or cochlear conductive, presbycusis problem with movement inside cochlea
etiology of presbycusis no widely accepted etiology, various contributing factors
presbycusis CMs progressive decrease in hearing thresholds, decreased ability to understand speech
presbycusis diagnosis history and complete audiologic assessment
presbycusis treatment hearing aids, assistive listening devices, cochlear implants (very few cases, put in at head and works like cochlea to capture sound waves)
meniere disease inner ear disorder with both auditory and vestibular symptoms
meniere disease occurs when there is excess endolymph within membranous labyrinth of inner ear
CMs of meniere disease Intense vertigo with accompanying nausea and vomiting Tinnitus Pressure or fullness in the ear Fluctuating hearing loss
tinnitus always hear something ringing
fluctuating hearing loss comes and goes
ototoxicity side effect of some medications that affect sensory cells
ototoxicity damages sensory cells of inner ear
cochleotoxic medications affect cochlea
cochleotoxic medications damages sensory cells of cochlea
cochleotoxic medications causes sensorineural hearing loss - typically bilateral
cestibulotoxic medications affect peripheral system
cestibulotoxic medications damage sensory cells of peripheral balance system
cestibulotoxic medications effects typicallt bilateral
factors affecting extent of ototoxic affects age, coexisiting medial conditions, genetic predisposition, drug in use/dosage/schedule
most widely use ototoxic medications aminoglycoside antibiotics platinum based antinoplastic medications
genetic hearing loss is one of the most common birth defects
genetic hearing loss is caused by genetic mutation
CMs of genetic hearing loss Nonsyndromic hearing loss Syndromic hearing loss
Nonsyndromic hearing loss hearing loss ONLY, all other senses are normal
Syndromic hearing loss accompanied by pattern of other clinical abnormalities
diagnosis of genetic hearing loss physical attributes related to syndrome genetic testing for definitive diagnosis
treatment of genetic hearing loss Regular audiologic monitoring Sensorineural hearing loss Conductive hearing loss
Sensorineural hearing loss uses Hearing aid or cochlear implant
Conductive hearing loss uses Hearing aid or osseointegrated hearing implant
internal structures of the eye light enters eye through cornea, crosses anterior, through pupil, through lens, image is inverted in lens inverted light lands on retina optic nerve exits back of eye at optic disc
myopia nearsightedness, image focused in front of the lens blurry objects from far away
hyperopia farsightedness, eyeball is too small, image focused behind the retina problems with seeing close up
hyperopia is corrected by contacts
presbyopia is age related
presbyopia farsightedness associated with aging, loss of elasticity reduces accommodation, ciliary muscles weakening and the eye's kens becoming less flexible
astigmatism irregular curvature in the cornea or lens, affects far vision mostly but can affect both
strabismus result from deviation of one eye, double vision (diplopia), may be caused by weak or hypertonic muscle, short muscle or neurological defect
strabismus in children must be treated immediately to prevent development of amblyopia (induced bc brain is used to only moving one eye)
nystagmus rapid, involuntary eye movement develops in some individuals with amblyopia and strabismus may result from neurological causes, inner ear or cerebral disturbance, drug toxicity
inhered diplopia result from neurological causes (stroke), paralysis of extraocular muscle, loss of depth perception
vision disorders: color blindness types Red/green color blindness (most common) Blue/yellow color blindness Achromotopsia (most severe)
vision disorders: color blindness can be Congenital or acquired
infection: Hordeolum (stye) Tender, red, often pus-filled bump along edge of eyelid Bacterial infection in oil glands at base of eyelash Resolved in week without treatment
Infection: Conjunctivitis (pinkeye) symptoms Redness, discharge, itching, burning of eyes Increased tearing; blurred vision, light sensitivity
Viral Conjunctivitis (most common) Adenoviruses; herpes simplex virus Resolves in 7-21 days
Bacterial Conjunctivitis (chlamydia) Resolves within 1 week Symptoms persist up to 3 weeks Topical antibiotics
Allergic Conjunctivitis Not contagious Treated with saline and/or oral and topical medications
Infection: Pterygium Benign growth or conjunctiva; may extend to cornea
Infection: Pterygium risk factors High levels of exposure to UV light, wind and/or airborne irritants
Infection: Pterygium causes for removal Unsightly Interferes with vision Causes discomfort
Infection: Keratitis Severe pain and photophobia: develops when cornea is infected or irritated Transfer from herpes lesion around mouth Increase the risk of ulceration eroding the cornea Scar formation damage the cornea
Infection: Keratitis cause damage from chemicals, splashes and fume
corneal abrasion Scratch or cut on cornea
corneal abrasion causes Foreign body or chemical irritant Rubbing eye too forcefully or being poked in eye
corneal abrasion symptoms Eye redness, tearing, eye pain, blurred vision, light sensitivity
corneal abrasion treatment Flushing with water or a sterile saline solution Topical antibiotics and anti-inflammatories
vision disorders: cataracts Cloudy or opaque discoloration of lens
cataracts causes Age related changes (most common), trauma, congenital anomalies, systemic disease, pharmacologic triggers
cataracts diagnosis Ophthalmologic exam
cataracts treatment Laser to destroy cloudy area Limit exposure to UV light Surgery; ultrasonic vibrations; artificial lens Capsulotomy
Capsulotomy cut part of the lens in part that won’t affect vision
vision disorders: glaucoma Increase in intraocular pressure (due to inability to drain aqueous humors) Leads to slow, painless, progressive loss of vision Numerous risk factors Cause of blindness
glaucoma signs and symptoms Initially asymptomatic Halos around the eye at night Loss of peripheral vision Pain may occur if IOP is greatly increased
Vision Disorders: Acute Glaucoma (narrow angle) Angle between cornea and iris decreased, decreased ability to drain aqueous humor
Acute Glaucoma (narrow angle) cause Aging developmental abnormalities, trauma or infection
Acute Glaucoma (narrow angle) treatment surgery
Vision Disorders: Acute Glaucoma (open-angle) Higher in older than 50 - aging is a main cause Thickness of trabecular network which allows for resorption of fluid, blocks drainage of aqueous humor Pressure increase over time: may cause damage to the retina or optic nerve
Acute Glaucoma (open-angle) is Irreversible and may cause blindness 2nd leading cause of blindness!!!
Vision Disorders: Retinopathy Any disorder of, or damage to, retina Retinal detachment - doesn’t cause pain Retina separates from underlying structures
Diabetic retinopathy leading cause of blindness in US
Non-proliferative diabetic retinopathy no angiogenesis, no regeneration of vasculature
proliferative diabetic retinopathy angiogenesis, new vasculature formation in proliferation
Retinopathy risk factors Significant myopia Cataract surgery; PDR, trauma!
Vision Disorders: Macular degeneration Age related, complication of aging Macula degenerates; distortion or loss of central vision because losing cons/rods
Dry macular degeneration Most common Blurring or “wavy” central vision with normal peripheral vision
Wet macular degeneration More severe New blood vessels grow around macula - angiogenesis happens in macula which induces damage Causes bleeding, scarring and photoreceptor atrophy
Created by: leh195
 

 



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