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patho exam 3
eye and hearing disorders
| Question | Answer |
|---|---|
| structures within ear | hear and interpret sounds provide information about position and movement of head in space |
| receptors within eye | shapes and colors conveyed in light energy |
| impairments | alter information available to cortex to process disease, aging, medications, environmental factors, genetics |
| disorders of hearing, balance, vision have a | negative effect on overall quality of life |
| children born with hearing or vision deficits | developmental, communication, mobility delays |
| adults with vision or hearing loss | problems with mobility, nutrition, stress, coping, mood, affect increased susceptibility to environmental issues |
| hearing process | sound waves transformed into neural impulses pitch, loudness, timing preserved at each step, allowing brain to perceive sound accurately |
| pathologies of the auditory system disrupt | normal sound transmission |
| types of hearing loss | sensorineural - makes sense of sounds conductive - conducts vibrations of sound waves mixed |
| auricle (pinna) | collects sound pressure waves; directs them into external auditory canal generates cues about timing and intensity of sounds to localize |
| ossicles | malleus (largest); incus; stapes attached oval window, which leads to fluid filled inner ear |
| external acoustic meatus ends at | tympanic membrane, or eardrum |
| external acoustic meatus is lined with | hairs and glands that secrete cerumen to protect the rest of hearing system from dust/debris |
| tympanic membrane | sound receptor and transmitter, vibrations transmitted to ossicles |
| neural signal pathway | along auditory portion of the vestibulocochlear nerve, exits cochlea via internal auditory canal, travels through multiple nuclei in brainstem, proceeds to thalamus, reaches primary auditory cortex, located in temporal lobe |
| inner ear: bony labyrinth consists of | cochlea (hearing), the vestibule (acceleration) and the three semicircular canals (balance) |
| inner ear: bony labyrinth | system of canals in temporal bone fluid filled membranous labyrinth |
| inner ear: cochlea canals | where waves of sounds make sense, scala vestibuli, scala media, scala tympani |
| inner ear: cochlea are filled with | perilymph (similar to CSF) |
| inner ear: cochlea = | pressure windows |
| kinetic labyrinth | semicircular ducts in semicircular canals - anterior, posterior, lateral |
| static labyrinth | utricle in vestibule saccule in vestibule |
| peripheral balance system: possible effects of loss of peripheral balance function | vertigo feelings of unsteadiness visual blurring hearing sensitivity |
| peripheral balance system: causes of balance disruption | certain diseases and conditions central vestibular disorders some medications |
| conductive hearing loss disorders | sound unable to travel normally to inner ear reflects audibility problem |
| types of conductive hearing loss | outer ear disorders otitis media - most common of middle ear otosclerosis - disorder of middle ear |
| outer ear disorders are | highly treatable (most) |
| outer ear disorders typically do not involve hearing loss except | congenital outer ear malformations |
| some common outer ear disorders | cerumen impaction, collapsed ear canal, external otitis, stenosis of ear canal, microtia or anotia |
| otitis media (OM) is the inflammation of | middle ear space |
| otitis media (OM) | associated with eustachian tube dysfunction because exudate blocks eustachian and nasal tube which blocks the membrane and causes a respiratory problem |
| otitis media (OM) CMs | coldlike symptoms and/or upper respiratory problems |
| acute otitis media (OM) | inflammation of middle ear with acute onset moderate to severe bulging of TM and middle ear effusion |
| acute otitis media (OM) complications | rupture TM conductive hearing loss (temporary) |
| acute otitis media (OM) treatment | antibiotics |
| reccurent otitis media (OM) | Three or more episodes of AOM in 6 months or four or more episodes in 12 months |
| factors that increase risk of reccurence of reccurent otitis media (OM) | male gender, passive exposure to smoking, winter season |
| chronic otitis media | infection longer than six weeks with persistent effusion in middle ear space mild to moderate conductive hearing loss (if not treated) |
| chronic otitis media treatment | topical antibiotics and/or steroids frequent cleaning of ear canal (tube to drain exudate from canal) |
| severe cases of chronic otitis media treatment | surgical intervention and/or systemic antibiotics ventilation/pressure equalization (PE) tubes |
| ostosclerosis is | the abnormal bone growth in middle ear space which blocks sounds and the ossicle enlarged |
| associated hearing loss | Bilateral - lose hearing in both ears Slowly progressive Conductive - can be mixed if otic capsule is involved |
| etiology and pathogenesis of ostosclerosis | Alternating bone resorption and formation Genetic component as autosomal dominant Viral factors Autoimmune system disorders |
| diagnosis of ostosclerosis | Patient history Otoscopy Audiologic results Radiologic results |
| treatment of ostosclerosis | Annual hearing tests to monitor hearing loss Surgical procedures - diminish size of ossicles Hearing aids Fluoride, calcium, vitamin D - nutritional components |
| presbycusis is | hearing loss due to aging |
| presbycusis is the most common form of | hearing loss |
| four types of presbycusis | Sensory presbycusis Neural presbycusis Metabolic, or strial, presbycusis Mechanical, or cochlear conductive, presbycusis |
| Sensory presbycusis | problem with cochlea |
| Neural presbycusis | problem with CNs |
| Mechanical, or cochlear conductive, presbycusis | problem with movement inside cochlea |
| etiology of presbycusis | no widely accepted etiology, various contributing factors |
| presbycusis CMs | progressive decrease in hearing thresholds, decreased ability to understand speech |
| presbycusis diagnosis | history and complete audiologic assessment |
| presbycusis treatment | hearing aids, assistive listening devices, cochlear implants (very few cases, put in at head and works like cochlea to capture sound waves) |
| meniere disease | inner ear disorder with both auditory and vestibular symptoms |
| meniere disease occurs when there is | excess endolymph within membranous labyrinth of inner ear |
| CMs of meniere disease | Intense vertigo with accompanying nausea and vomiting Tinnitus Pressure or fullness in the ear Fluctuating hearing loss |
| tinnitus | always hear something ringing |
| fluctuating hearing loss | comes and goes |
| ototoxicity | side effect of some medications that affect sensory cells |
| ototoxicity damages | sensory cells of inner ear |
| cochleotoxic medications affect | cochlea |
| cochleotoxic medications damages | sensory cells of cochlea |
| cochleotoxic medications causes | sensorineural hearing loss - typically bilateral |
| cestibulotoxic medications affect | peripheral system |
| cestibulotoxic medications damage | sensory cells of peripheral balance system |
| cestibulotoxic medications effects | typicallt bilateral |
| factors affecting extent of ototoxic affects | age, coexisiting medial conditions, genetic predisposition, drug in use/dosage/schedule |
| most widely use ototoxic medications | aminoglycoside antibiotics platinum based antinoplastic medications |
| genetic hearing loss is | one of the most common birth defects |
| genetic hearing loss is caused by | genetic mutation |
| CMs of genetic hearing loss | Nonsyndromic hearing loss Syndromic hearing loss |
| Nonsyndromic hearing loss | hearing loss ONLY, all other senses are normal |
| Syndromic hearing loss | accompanied by pattern of other clinical abnormalities |
| diagnosis of genetic hearing loss | physical attributes related to syndrome genetic testing for definitive diagnosis |
| treatment of genetic hearing loss | Regular audiologic monitoring Sensorineural hearing loss Conductive hearing loss |
| Sensorineural hearing loss uses | Hearing aid or cochlear implant |
| Conductive hearing loss uses | Hearing aid or osseointegrated hearing implant |
| internal structures of the eye | light enters eye through cornea, crosses anterior, through pupil, through lens, image is inverted in lens inverted light lands on retina optic nerve exits back of eye at optic disc |
| myopia | nearsightedness, image focused in front of the lens blurry objects from far away |
| hyperopia | farsightedness, eyeball is too small, image focused behind the retina problems with seeing close up |
| hyperopia is corrected by | contacts |
| presbyopia is | age related |
| presbyopia | farsightedness associated with aging, loss of elasticity reduces accommodation, ciliary muscles weakening and the eye's kens becoming less flexible |
| astigmatism | irregular curvature in the cornea or lens, affects far vision mostly but can affect both |
| strabismus | result from deviation of one eye, double vision (diplopia), may be caused by weak or hypertonic muscle, short muscle or neurological defect |
| strabismus in children | must be treated immediately to prevent development of amblyopia (induced bc brain is used to only moving one eye) |
| nystagmus | rapid, involuntary eye movement develops in some individuals with amblyopia and strabismus may result from neurological causes, inner ear or cerebral disturbance, drug toxicity |
| inhered diplopia | result from neurological causes (stroke), paralysis of extraocular muscle, loss of depth perception |
| vision disorders: color blindness types | Red/green color blindness (most common) Blue/yellow color blindness Achromotopsia (most severe) |
| vision disorders: color blindness can be | Congenital or acquired |
| infection: Hordeolum (stye) | Tender, red, often pus-filled bump along edge of eyelid Bacterial infection in oil glands at base of eyelash Resolved in week without treatment |
| Infection: Conjunctivitis (pinkeye) symptoms | Redness, discharge, itching, burning of eyes Increased tearing; blurred vision, light sensitivity |
| Viral Conjunctivitis (most common) | Adenoviruses; herpes simplex virus Resolves in 7-21 days |
| Bacterial Conjunctivitis (chlamydia) | Resolves within 1 week Symptoms persist up to 3 weeks Topical antibiotics |
| Allergic Conjunctivitis | Not contagious Treated with saline and/or oral and topical medications |
| Infection: Pterygium | Benign growth or conjunctiva; may extend to cornea |
| Infection: Pterygium risk factors | High levels of exposure to UV light, wind and/or airborne irritants |
| Infection: Pterygium causes for removal | Unsightly Interferes with vision Causes discomfort |
| Infection: Keratitis | Severe pain and photophobia: develops when cornea is infected or irritated Transfer from herpes lesion around mouth Increase the risk of ulceration eroding the cornea Scar formation damage the cornea |
| Infection: Keratitis cause | damage from chemicals, splashes and fume |
| corneal abrasion | Scratch or cut on cornea |
| corneal abrasion causes | Foreign body or chemical irritant Rubbing eye too forcefully or being poked in eye |
| corneal abrasion symptoms | Eye redness, tearing, eye pain, blurred vision, light sensitivity |
| corneal abrasion treatment | Flushing with water or a sterile saline solution Topical antibiotics and anti-inflammatories |
| vision disorders: cataracts | Cloudy or opaque discoloration of lens |
| cataracts causes | Age related changes (most common), trauma, congenital anomalies, systemic disease, pharmacologic triggers |
| cataracts diagnosis | Ophthalmologic exam |
| cataracts treatment | Laser to destroy cloudy area Limit exposure to UV light Surgery; ultrasonic vibrations; artificial lens Capsulotomy |
| Capsulotomy | cut part of the lens in part that won’t affect vision |
| vision disorders: glaucoma | Increase in intraocular pressure (due to inability to drain aqueous humors) Leads to slow, painless, progressive loss of vision Numerous risk factors Cause of blindness |
| glaucoma signs and symptoms | Initially asymptomatic Halos around the eye at night Loss of peripheral vision Pain may occur if IOP is greatly increased |
| Vision Disorders: Acute Glaucoma (narrow angle) | Angle between cornea and iris decreased, decreased ability to drain aqueous humor |
| Acute Glaucoma (narrow angle) cause | Aging developmental abnormalities, trauma or infection |
| Acute Glaucoma (narrow angle) treatment | surgery |
| Vision Disorders: Acute Glaucoma (open-angle) | Higher in older than 50 - aging is a main cause Thickness of trabecular network which allows for resorption of fluid, blocks drainage of aqueous humor Pressure increase over time: may cause damage to the retina or optic nerve |
| Acute Glaucoma (open-angle) is | Irreversible and may cause blindness 2nd leading cause of blindness!!! |
| Vision Disorders: Retinopathy | Any disorder of, or damage to, retina Retinal detachment - doesn’t cause pain Retina separates from underlying structures |
| Diabetic retinopathy | leading cause of blindness in US |
| Non-proliferative diabetic retinopathy | no angiogenesis, no regeneration of vasculature |
| proliferative diabetic retinopathy | angiogenesis, new vasculature formation in proliferation |
| Retinopathy risk factors | Significant myopia Cataract surgery; PDR, trauma! |
| Vision Disorders: Macular degeneration | Age related, complication of aging Macula degenerates; distortion or loss of central vision because losing cons/rods |
| Dry macular degeneration | Most common Blurring or “wavy” central vision with normal peripheral vision |
| Wet macular degeneration | More severe New blood vessels grow around macula - angiogenesis happens in macula which induces damage Causes bleeding, scarring and photoreceptor atrophy |