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toxo ch 18

QuestionAnswer
Automaticity SA node P cells generate pacemaker potential, brings membrane potential to near threshold, allows Ca++ influx ® phase 0 rapid depolarization
Contractility myocyte contraction occurs when AP causes EC Ca++ influx ® Ca++ release from SE = excitation-contraction coupling; contraction strength directly proportional to [Ca++]
Electrotonic Cell-to-Cell Coupling gap junctions spread Na+ rapidly between adjacent cardiomyocytes, allows synchronization
Neurohormonal Regulation SA node generates cardiac cycle; ANS regulation controls cardiac function under normal & abnormal conditions
Cardiac Output 1° indicator of cardiac function; dependent on heart rate & stroke volume – resting: ~5L/min in avg adult; w/ strenuous exercise: ­ > 35L/min
•Cardiac Output 1° indicator of cardiac function; dependent on heart rate & stroke volume – resting: ~5L/min in avg adult; w/ strenuous exercise: ­ > 35L/min
Action potential depolarization to completion of repolarization
Cardiac AP: five phases Phase 0, Phase 1, Phase 2, Phase 3, Phase 4
Electrocardiogram Three waves P wave, R wave (QRS complex), T wave
Created by: aceofspades08
 

 



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