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M04
| Question | Answer |
|---|---|
| What is the main function of the respiratory system? | To exchange gases by supplying O2 to cells and removing CO2 while helping maintain acid-base balance. |
| Function of the respiratory system | Removes CO2, maintains blood pH balance, and supplies oxygen to all body cells. |
| What do nasal passages and cavity do? | Filter, warm, and humidify incoming air while trapping particles using mucus and hair. |
| Nasal cavity and passages | Part of innate immune defense; warms, humidifies, and filters air; mucus and hairs trap debris. |
| What are nasal conchae? | Curled bony structures that swirl inhaled air. |
| Conchae | Bony projections that increase surface area and turbulence, warming, humidifying, and filtering incoming air. |
| Where does gas exchange occur? | In the alveoli. |
| Alveoli | Microscopic air sacs with simple squamous epithelium for rapid gas diffusion; contain macrophages to remove debris. |
| What is the larynx? | The voice box that contains vocal cords. |
| Larynx | Voice box located above trachea; contains vocal cords; formed by thyroid, cricoid, and epiglottic cartilage. |
| What are the 3 cartilages of the larynx? | Thyroid, cricoid, and epiglottic cartilage. |
| Laryngeal cartilages | Thyroid (Adams apple), cricoid (below thyroid), and epiglottic (forms flap of epiglottis). |
| What is the function of the epiglottis? | Prevents food and liquids from entering the airway during swallowing. |
| Epiglottis | Flap of elastic cartilage that closes over glottis when swallowing and opens for breathing. |
| What is the glottis? | The opening between true vocal cords. |
| Glottis | Space between vocal folds; controls voice pitch and airflow; closes during swallowing and hiccups. |
| What is the trachea composed of? | C-shaped cartilage rings. |
| Trachea | Windpipe lined with ciliated mucosa; supported by C-shaped hyaline cartilage to prevent airway collapse. |
| How is most oxygen transported? | Bound to hemoglobin. |
| Hemoglobin | Protein inside RBCs; heme group binds oxygen for transport to tissues. |
| What protects the airway lining? | Mucus and cilia. |
| Respiratory epithelium | Ciliated mucosa with goblet cells that trap particles and sweep them toward pharynx. |
| What is external respiration? | Gas exchange between air in alveoli and blood in capillaries. |
| Respiration | Includes ventilation, external/internal gas exchange, and cellular respiration for ATP production. |
| What causes air to enter the lungs? | Pressure drops when diaphragm contracts. |
| Inspiration | Active process: diaphragm contracts, thoracic cavity expands, alveolar pressure decreases, air flows in. |
| What moves air out of the lungs? | Elastic recoil and surface tension. |
| Expiration | Passive phase of ventilation; muscles relax, lungs recoil, alveolar pressure increases, air flows out. |
| What is ventilation? | Movement of air in and out of lungs. |
| Ventilation | Includes minute ventilation and alveolar ventilation (air reaching alveoli). |
| What does Boyle’s Law state? | Pressure and volume of a gas are inversely related. |
| Boyle’s Law | As thoracic volume ↑, pressure ↓, allowing air to enter; opposite during exhalation. |
| How many lobes are in each lung? | Right has 3; left has 2. |
| Lung lobes | Right: superior, middle, inferior; Left: superior, inferior; left smaller due to cardiac notch. |
| What do type II alveolar cells secrete? | Surfactant. |
| Alveolar cell types | Type I = gas exchange surface; Type II = produce surfactant to reduce alveolar collapse. |
| What is tidal volume? | Amount of air inhaled/exhaled in a normal breath. |
| Tidal volume | ~500 mL normal quiet breathing air movement. |
| What is inspiratory reserve volume? | Additional air inhaled beyond tidal volume. |
| Inspiratory reserve volume | Maximum additional air that can be inhaled (~3000 mL). |
| What is vital capacity? | Maximum exhaled after maximum inhalation. |
| Vital capacity | IRV + TV + ERV. |
| Which brain parts control breathing? | Medulla and pons. |
| Respiratory control | Medulla sets rhythm; pons adjusts pace and smoothness. |
| What do chemoreceptors detect? | CO2, O2, and pH levels. |
| Chemoreceptors | Located in aorta, carotids, and brain; adjust breathing rate based on gas levels and pH. |
| Why is CO poisoning dangerous? | It binds hemoglobin stronger than oxygen. |
| Carbon monoxide toxicity | Competes with oxygen for hemoglobin binding (200x affinity), preventing O2 delivery to tissues. |
| What happens to alveoli in emphysema? | They lose elasticity and merge, reducing surface area. |
| Emphysema | COPD disease with damaged alveoli, decreased diffusion area, and increased work of breathing. |
| What causes asthma symptoms? | Airway inflammation and bronchoconstriction due to allergens. |
| Asthma | Triggers mucus buildup and smooth muscle contraction causing wheezing and restricted airflow. |
| What is pneumothorax? | Air leaks into pleural cavity, collapsing lung. |
| Pneumothorax | Air in pleural space increases pressure, reducing lung expansion. |
| What is Respiratory Distress Syndrome? | Lack of surfactant causing alveolar collapse. |
| Respiratory Distress Syndrome | Seen in premature infants; treated with oxygen and synthetic surfactant. |
| What is the main function of the respiratory system? | To remove CO2, maintain acid-base balance, and supply oxygen to all body cells. |
| Function of the respiratory system | Removes CO2, maintains pH balance, supplies O2 to tissues throughout the body. |
| What do nasal passages and cavity do? | Filter, warm, and humidify incoming air while trapping particles. |
| Nasal cavity and passages | Part of innate immune defense; warms, humidifies, and filters air; mucus and hairs trap debris. |
| What are nasal conchae? | Curled bony structures that swirl inhaled air. |
| Conchae | Bony projections that increase surface area and turbulence, warming, humidifying, and filtering incoming air. |
| Where does gas exchange occur? | In the alveoli. |
| Alveoli | Microscopic air sacs with thin simple squamous epithelium for rapid diffusion; contain macrophages that remove debris. |
| What is the larynx? | The voice box that houses vocal cords. |
| Larynx | Voice box above trachea; contains vocal cords; formed by thyroid, cricoid, and epiglottic cartilage. |
| What are the 3 cartilages of the larynx? | Thyroid, cricoid, and epiglottic cartilage. |
| Laryngeal cartilages | Thyroid = Adam’s apple; cricoid below thyroid; epiglottic forms epiglottis flap. |
| What is the function of the epiglottis? | Prevents food and liquid from entering the airway during swallowing. |
| Epiglottis | Elastic cartilage flap covering glottis during swallowing; opens during breathing. |
| What is the glottis? | The opening between the true vocal cords. |
| Glottis | Space between vocal folds; controls sound production and air flow. |
| What is the trachea composed of? | C-shaped cartilage rings. |
| Trachea | Windpipe supported by hyaline cartilage rings; lined with cilia and mucus producing cells. |
| How is most oxygen transported? | Bound to hemoglobin. |
| Hemoglobin | Protein in RBCs with iron-containing heme units that bind and carry oxygen. |
| What protects the airway lining? | Mucus and cilia. |
| Respiratory epithelium | Ciliated mucous membrane with goblet cells that trap and sweep particles upward. |
| What is external respiration? | Gas exchange between air and blood in the lungs. |
| Respiration | Includes ventilation, external/internal gas exchange, and cellular respiration for ATP production. |
| What causes air to enter the lungs? | Pressure drops when diaphragm contracts. |
| Inspiration | Active process: diaphragm contracts, thoracic cavity expands, alveolar pressure drops, air flows in. |
| What moves air out of the lungs? | Elastic recoil and surface tension. |
| Expiration | Passive process where muscles relax and alveolar pressure rises pushing air out. |
| What is ventilation? | Movement of air in and out of lungs. |
| Ventilation | Includes minute ventilation and alveolar ventilation (air reaching alveoli). |
| What does Boyle’s Law state? | Pressure and volume of a gas are inversely related. |
| Boyle’s Law | As thoracic cavity volume increases, pressure falls and air flows in; reverse on exhalation. |
| How many lobes are in each lung? | Right = 3; left = 2. |
| Lung lobes | Right: superior, middle, inferior; Left: superior, inferior; left smaller due to cardiac notch. |
| What do type II alveolar cells secrete? | Surfactant. |
| Alveolar cell types | Type I = gas exchange surface; Type II = produce surfactant to reduce collapse and surface tension. |
| What is tidal volume? | Amount of air inhaled/exhaled in a normal breath. |
| Tidal volume | Approx. 500mL amount of air moved during quiet breathing. |
| What is inspiratory reserve volume? | Additional air inhaled beyond tidal volume. |
| Inspiratory reserve volume | Maximum additional air inhaled (~3000mL) after normal inspiration. |
| What is vital capacity? | Max exhaled after max inhalation. |
| Vital capacity | IRV + TV + ERV = maximum exchangeable lung air. |
| Which brain structures control breathing? | Medulla and pons. |
| Respiratory control | Medulla sets rhythm; pons modifies rate and smoothness. |
| What do chemoreceptors detect? | CO2, O2 and pH levels. |
| Chemoreceptors | Located in aorta, carotids and brain; adjust breathing rate and depth based on gas levels. |
| Why is carbon monoxide dangerous? | Binds hemoglobin stronger than oxygen and blocks O2 transport. |
| Carbon monoxide toxicity | CO has 200x affinity for hemoglobin over O2; prevents oxygen delivery to tissues. |
| What happens to alveoli in emphysema? | They lose elasticity and surface area. |
| Emphysema | Alveoli merge into large non-elastic sacs reducing gas exchange; form of COPD. |
| What causes asthma symptoms? | Airway inflammation and bronchoconstriction triggered by allergens. |
| Asthma | Allergic reaction causing mucus buildup and narrowed bronchioles resulting in wheezing. |
| What is pneumothorax? | Collapsed lung caused by air in the pleural space. |
| Pneumothorax | Air between lung and chest wall reduces expansion causing partial or full collapse. |
| What is RDS? | Breathing disorder due to lack of surfactant. |
| Respiratory Distress Syndrome | Seen in premature infants; alveoli collapse; treated with oxygen and synthetic surfactant. |