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UNIT 4, CHPT 13
CHAPTER 13.2
| Question | Answer |
|---|---|
| what is a semi conservative model? | DNA replication where the replicated double helix consists of one old strand and one new strand |
| what is a replication fork? | y-shaped region on replicating DNA where parental strands are being unwound and new strands are being synthesized |
| what are single strand binding proteins? | proteins that bind to unpaired DNA strands to keep them from repairing, stabilizing them |
| what is topisomerase? | protein that breaks, swivels, and rejoins DNA strands. helps to relieve strain in double helix ahead of the replication fork |
| what is a primer? | initial nucelotide chain produced during DNA synthesis, RNA. short polynucleotide synthesized by the enzyme primase. |
| what is a primase? | enzyme that joins RNA nucleotides to make a primer during DNA replication, using parental DNA strand as a template |
| what are DNA polymerases? | enzymes that catalyze the synthesis of new DNA by adding nucleotides to the 3' prime end of a preexisting chain. most require a primer and DNA template |
| what is a leading strand? | the new complimentary DNA strand synthesized continuously along the template strand toward the replication fork (in the mandatory 5' to 3' direction) |
| what is a lagging strand? | discontinuously synthesized DNA strand that elongates via okazaki fragments; each synthesized in a 5' to 3' direction away from the replication fork |
| what are okazaki fragments? | segments of the lagging strand |
| what is DNA ligase? | linking enzyme essential for DNA replication; joins pieces of DNA together |
| what is mismatched repair? | cellular process that uses specific enzymes to remove and replace incorrectly paired nucleotides |
| what is a nuclease? | DNA cutting enzyme; cuts DNA or RNA either by removing one/a few bases OR hydrolyzing the DNA/RNA completely into its component nucleotides |
| what is a nucleotide excision repair? | repair system that removes and then correctly replaces a damaged segment of DNA using the undamaged strand as a guide |
| what are telomeres? | repetitive DNA at the end of a chromosome's DNA molecule |