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UNIT 4, CHPT 13

CHAPTER 13.2

QuestionAnswer
what is a semi conservative model? DNA replication where the replicated double helix consists of one old strand and one new strand
what is a replication fork? y-shaped region on replicating DNA where parental strands are being unwound and new strands are being synthesized
what are single strand binding proteins? proteins that bind to unpaired DNA strands to keep them from repairing, stabilizing them
what is topisomerase? protein that breaks, swivels, and rejoins DNA strands. helps to relieve strain in double helix ahead of the replication fork
what is a primer? initial nucelotide chain produced during DNA synthesis, RNA. short polynucleotide synthesized by the enzyme primase.
what is a primase? enzyme that joins RNA nucleotides to make a primer during DNA replication, using parental DNA strand as a template
what are DNA polymerases? enzymes that catalyze the synthesis of new DNA by adding nucleotides to the 3' prime end of a preexisting chain. most require a primer and DNA template
what is a leading strand? the new complimentary DNA strand synthesized continuously along the template strand toward the replication fork (in the mandatory 5' to 3' direction)
what is a lagging strand? discontinuously synthesized DNA strand that elongates via okazaki fragments; each synthesized in a 5' to 3' direction away from the replication fork
what are okazaki fragments? segments of the lagging strand
what is DNA ligase? linking enzyme essential for DNA replication; joins pieces of DNA together
what is mismatched repair? cellular process that uses specific enzymes to remove and replace incorrectly paired nucleotides
what is a nuclease? DNA cutting enzyme; cuts DNA or RNA either by removing one/a few bases OR hydrolyzing the DNA/RNA completely into its component nucleotides
what is a nucleotide excision repair? repair system that removes and then correctly replaces a damaged segment of DNA using the undamaged strand as a guide
what are telomeres? repetitive DNA at the end of a chromosome's DNA molecule
Created by: SuperBugLover
 

 



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