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APC Final Exam
| Pharmacologic Category | Generic Name | Brand Name | Classification | Common Indications |
|---|---|---|---|---|
| Alpha2 antagonist | mirtazapine (PO) | Remeron | - | MDD |
| Norepinephrine dopamine reuptake inhibitor | bupropion (PO) | Wellbutrin SR, Wellbutrin XL | - | MDD |
| Selective norepinephrine reuptake inhibitor | atomoxetine (PO) | Strattera | - | ADHD |
| Serotonin-norepinephrine reuptake inhibitor (SNRI) | desvenlafaxine (PO) | Pristiq | - | MDD |
| Serotonin-norepinephrine reuptake inhibitor (SNRI) | duloxetine (PO) | Cymbalta | - | MDD, neuropathic pain |
| Serotonin-norepinephrine reuptake inhibitor (SNRI) | venlafaxine (PO) | Effexor XR | - | MDD |
| Selective serotonin reuptake inhibitor (SSRI) | citalopram (PO) | Celexa | - | MDD |
| Selective serotonin reuptake inhibitor (SSRI) | fluoxetine (PO) | Prozac | - | MDD |
| Selective serotonin reuptake inhibitor (SSRI) | escitalopram (PO) | Lexapro | - | MDD |
| Selective serotonin reuptake inhibitor (SSRI) | paroxetine (PO) | Paxil | - | MDD |
| Selective serotonin reuptake inhibitor (SSRI) | sertraline (PO) | Zoloft | - | MDD |
| Serotonin reuptake inhibitor | trazodone (PO) | Desyrel | - | Insomnia, MDD |
| Tricyclic antidepressant (TCA) | amitriptyline (PO) | Elavil | - | MDD, diabetic neuropathy, migraine prophylaxis |
| Tricyclic antidepressant (TCA) | nortriptyline (PO) | Pamelor | - | MDD, diabetic neuropathy, migraine prophylaxis |
| Tricyclic antidepressant (TCA) | doxepin (PO) | Silenor | - | Insomnia |
| CNS stimulant | dexmethylphenidate (PO) | Focalin, Focalin XR | CS-II | ADHD |
| CNS stimulant | dextroamphetamine and amphetamine (PO) | Adderall, Adderall XR | CS-II | ADHD, narcolepsy |
| CNS stimulant | lisdexamfetamine (PO) | Vyvanse | CS-II | ADHD |
| CNS stimulant | methylphenidate (PO, transdermal) | PO: Concerta, Ritalin Patch: Daytrana | CS-II | ADHD, narcolepsy |
| Selective alpha2a antagonist | guanfacine (PO) | Intuniv | - | ADHD, HTN |
| Dopamine agonist | pramipexole (PO) | Mirapex | - | Parkinson's disease, RLS |
| Dopamine agonist | ropinirole (PO) | Requip | - | Parkinson's disease, RLS |
| Decarboxylase inhibitor (carbidopa), dopamine precursor (levodopa) | carbidopa and levodopa (PO) | Sinemet, Sinemet CR | - | Parkinson's disease |
| N-methyl D-aspartate (NMDA) antagonist | memantine (PO) | Namenda | - | Dementia |
| Cholinesterase inhibitor | donepezil (PO, transdermal) | PO: Aricept, Transdermal: Adlarity | - | Dementia |
| Antimanic agent | lithium (PO) | Lithobid | - | Bipolar disorder |
| Antimigraine | sumatriptan (PO, intranasal, SQ) | Imitrex | - | Migraine |
| Antimigraine | rizatriptan (PO) | Maxalt | - | Migraine |
| First-generation antipsychotic | haloperidol (PO, IV, IM) | Haldol | - | Schizophrenia |
| Second-generation antipsychotic | clozapine (PO) | Clozarol | - | Treatment-resistant schizophrenia |
| Second-generation antipsychotic | aripiprazole (PO, IM) | PO/IM: Abilify; IM: Aristada | - | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) |
| Second-generation antipsychotic | quetiapine (PO) | Seroquel, Seroquel XR | - | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) |
| Second-generation antipsychotic | lurasidone (PO) | Latuda | - | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) |
| Second-generation antipsychotic | olanzapine (PO, IM) | Zyprexa | - | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) |
| Second-generation antipsychotic | risperidone (PO, IM) | PO: Risperdal IM: Risperdal Consta | - | Schizophrenia |
| Anticonvulsant | carbamazepine (PO) | Tegretol | - | Seizure disorders, bipolar disorder |
| Anticonvulsant | lamotrigine (PO) | Lamictal | - | Seizure disorders, bipolar disorder |
| Anticonvulsant | divalproex (valproic acid derivative) (PO) | Depakote, Depakote ER | - | Seizure disorders, bipolar disorder, migraine prophylaxis |
| Anticonvulsant | topiramate (PO) | Topamax | - | Seizure disorders, migraine prophylaxis |
| Anticonvulsant | levetiracetam (PO, IV) | Keppra | - | Seizure disorders |
| Anticonvulsant | oxcarbazepine (PO) | Trileptal | - | Seizure disorders |
| Anticonvulsant | gabapentin (PO) | Neurontin | - | Seizure disorders, neuropathic pain |
| Anticonvulsant | pregabalin (PO) | Lyrica | CS-V | Seizure disorders, neuropathic pain |
| Antianxiety agent | buspirone (PO) | Buspar | - | Anxiety |
| Benzodiazepine | alprazolam (PO) | Xanax | CS-IV | Anxiety |
| Benzodiazepine | clonazepam (PO) | Klonopin | CS-IV | Anxiety, seizure disorders |
| Benzodiazepine | diazepam (PO, IV) | Valium | CS-IV | Anxiety, seizure disorders, acute alcohol withdrawal |
| Benzodiazepine | lorazepam (PO, IV) | Ativan | CS-IV | Anxiety, seizure disorders, acute alcohol withdrawal |
| Benzodiazepine | midazolam (IV, IM) | Versed | CS-IV | Anesthesia, sedation |
| Hypnotic | zolpidem (PO) | PO: Ambien, Ambien CR SL: Edluar | CS-IV | Insomnia |
| Sleep aid | melatonin (PO) | - | OTC | Insomnia, jet lag |
| Sedative, general anesthetic | propofol (IV) | Diprivan | - | Sedation for mechanical ventilation, procedural anesthesia, status epilepticus |
| Alpha2 agonist, sedative | dexmedetomidine (IV) | Precedex | - | Sedation for mechanical ventilation or procedures |
| Inhaled corticosteroid (ICS) | budesonide (INH) | Pulmicort | - | Asthma, COPD |
| Inhaled corticosteroid (ICS) | fluticasone propionate (INH) | Flovent, Arnuity | - | Asthma, COPD |
| Inhaled corticosteroid (ICS) and long-acting beta2 agonist (LABA) | fluticasone and salmeterol (INH) | Advair, Wixela | - | Asthma, COPD |
| Inhaled corticosteroid (ICS) and long-acting beta2 agonist (LABA) | budesonide and formoterol (INH) | Symbicort, Breyna | - | Asthma, COPD |
| Inhaled corticosteroid (ICS) and long-acting beta2 agonist (LABA) | mometasone and formoterol (INH) | Dulera | - | Asthma, COPD |
| Inhaled corticosteroid (ICS), long-acting beta2 agonist (LABA), and long-acting muscarinic antagonist (LAMA) | umeclidinium + vilanterol + fluticasone (INH) | Trelegy Ellipta | - | Asthma, COPD |
| Long-acting muscarinic antagonist (LAMA) | tiotropium (INH) | Spiriva | - | Asthma, COPD |
| Short-acting beta2 agonist (SABA) | albuterol (INH) | Proventil, Ventolin, ProAir | - | Asthma, COPD |
| Leukotriene receptor antagonist | montelukast (PO) | Singulair | - | Allergic rhinitis, asthma |
| Partial nicotine agonist | varenicline (PO) | Chantix | - | Smoking cessation |
| Alpha2 agonist | tizanidine (PO) | Zanaflex | - | Spasticity |
| Aminoquinolone | hydroxychloroquine (PO) | Plaquenil | - | Rheumatoid arthritis, systemic lupus erythematosus, malaria |
| NSAID | diclofenac (topical) | Voltaren Gel | OTC | Osteoarthritis |
| NSAID | diclofenac (PO) | Voltaren | - | Osteoarthritis, rheumatoid arthritis, acute pain |
| NSAID | ibuprofen (PO) | Motrin, Advil | OTC | Osteoarthritis, rheumatoid arthritis, acute pain |
| NSAID | meloxicam (PO) | Mobic | - | Osteoarthritis, rheumatoid arthritis, acute pain |
| NSAID | indomethacin (PO) | Indocin | - | Osteoarthritis, rheumatoid arthritis, acute pain, gout |
| NSAID | naproxen (PO) | Naprosyn, Anaprox, Aleve | OTC | Osteoarthritis, rheumatoid arthritis, acute pain, gout |
| NSAID | ketorolac (PO, IV) | Toradol | - | Pain |
| NSAID, COX-2 selective | celecoxib (PO) | Celebrex | - | Osteoarthritis, rheumatoid arthritis, acute pain |
| Skeletal muscle relaxant | cyclobenzaprine (PO) | Flexeril, Amrix, Fexmid | - | Muscle spasm |
| Skeletal muscle relaxant | baclofen (PO) | - | - | Spasticity |
| Skeletal muscle relaxant | methocarbamol (PO) | Robaxin | - | Muscle spasm |
| Transdermal: topical analgesic IV: antiarrhythmic | lidocaine (transdermal, IV) | Transdermal: Lidoderm, IV: Xylocaine | Transdermal: OTC | Transdermal: pain, IV: ventricular arrhythmias |
| Antigout agent | colchicine (PO) | Colcrys | - | Gout |
| Xanthine oxidase Inhibitor | allopurinol (PO) | Zyloprim | - | Gout |
| Depolarizing neuromuscular blocking agent | succinylcholine (IV) | Anectine | - | Neuromuscular blockade for intubation or procedures |
| Anti-tumor necrosis factor alpha inhibitor | etanercept (SQ) | Enbrel | - | Rheumatoid arthritis |
| Anti-tumor necrosis factor alpha inhibitor | adalimumab (SQ) | Humira | - | Rheumatoid arthritis, Crohn's disease, Ulcerative Colitis |
| Opioid analgesic | fentanyl (transdermal, IV) | Transdermal: Duragesic, IV: Sublimaze | CS-II | Pain |
| Opioid analgesic | hydromorphone (PO, IV) | Dilaudid | CS-II | Pain |
| Opioid analgesic | morphine (extended release) (PO) | MS Contin, Kadian | CS-II | Pain |
| Opioid analgesic | morphine (immediate release) (PO, IV, IM, PR) | IV: Duramorph, Infumorph | CS-II | Pain |
| Opioid analgesic | oxycodone (PO) | OxyContin, Roxicodone | CS-II | Pain |
| Opioid analgesic | methadone (PO, IV) | Dolophine | CS-II | Opioid use disorder, severe chronic pain |
| Analgesic (non-opioid), antipyretic | acetaminophen (PO, PR, IV) | PO/PR: Tylenol, IV: Ofirmev | PO, PR: OTC | Pain, fever |
| Central analgesic; partial opioid agonist | tramadol (PO) | Ultram, Ultram ER | CS-IV | Pain |
| Opioid and nonopioid analgesic combination | hydrocodone and acetaminophen (PO) | Lortab, Vicodin, Norco | CS-II | Pain |
| Opioid and nonopioid analgesic combination | oxycodone and acetaminophen (PO) | Percocet, Endocet | CS-II | Pain |
| Opioid and nonopioid analgesic combination | codeine and acetaminophen (PO) | Tylenol with Codeine #3, Tylenol with Codeine #4 | CS-III | Pain |
| Opioid antagonist | naloxone (IV, IM, SQ, intranasal) | Narcan Nasal Spray, Zimhi | Narcan Nasal Spray: OTC | Opioid overdose |
| Partial opioid agonist and opioid antagonist | buprenorphine and naloxone (SL) | Suboxone | CS-III | Opioid use disorder |
| Iron supplement | ferrous sulfate (PO) | FeroSul, SlowFe | OTC | Iron deficiency anemia |
| Water-soluble vitamin | cyanocobalamin (vitamin B12) (PO, IM, SL, intranasal) | - | PO, SL: OTC | Vitamin B12 deficiency (manifests as macrocytic anemia) |
| Water-soluble vitamin | folic acid (PO) | - | OTC | Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy |
| Antimetabolite (folic acid antagonist) | methotrexate (PO, IV, IT) | Trexall | - | Rheumatoid arthritis, Crohn’s Disease, psoriasis, various hematologic and solid tumors |
| Antineoplastic agent, platinum-based compound | cisplatin (IV, IT, IP) | Kemoplat | - | Advanced bladder, ovarian, and testicular cancer; various cancers |
| Antineoplastic agent, anthracycline | doxorubicin (IV) | Adriamycin | - | Adjuvant therapy for breast cancer, various cancers |
| Antineoplastic agent, monoclonal antibody | pembrolizumab (IV) | Keytruda | - | Various cancers |
| Aromatase inhibitor | anastrozole (PO) | Arimidex | - | Hormone receptor-positive breast cancer |
| Selective estrogen receptor modulator (SERM) | tamoxifen (PO) | Soltamox | - | Hormone receptor-positive breast cancer |
| Angiotensin-converting enzyme (ACE) inhibitor | benazepril (PO) | Lotensin | - | Hypertension, heart failure, Coronary artery disease |
| Angiotensin-converting enzyme (ACE) inhibitor | enalapril (PO) | Vasotec | - | Hypertension, heart failure, Coronary artery disease |
| Angiotensin-converting enzyme (ACE) inhibitor | lisinopril (PO) | Prinivil, Zestril | - | Hypertension, heart failure, Coronary artery disease |
| Angiotensin-converting enzyme (ACE) inhibitor | ramipril (PO) | Altace | - | Hypertension, heart failure, Coronary artery disease |
| Angiotensin II receptor blocker (ARB) | irbesartan (PO) | Avapro | - | Hypertension, heart failure, Coronary artery disease |
| Angiotensin II receptor blocker (ARB) | losartan (PO) | Cozaar | - | Hypertension, heart failure, Coronary artery disease |
| Angiotensin II receptor blocker (ARB) | olmesartan (PO) | Benicar | - | Hypertension, heart failure, Coronary artery disease |
| Angiotensin II receptor blocker (ARB) | valsartan (PO) | Diovan | - | Hypertension, heart failure, Coronary artery disease |
| ARB and neprilysin inhibitor (ARNI) | valsartan and sacubitril (PO) | Entresto | - | Heart failure |
| Dihydropyridine calcium channel blocker (CCB) | amlodipine (PO) | Norvasc | - | Hypertension, coronary artery disease |
| Dihydropyridine calcium channel blocker (CCB) | nifedipine ER (PO) | Procardia XL, Adalat CC | - | Hypertension, coronary artery disease |
| Dihydropyridine calcium channel blocker (CCB) | nicardipine (PO, IV) | Cardene | - | Hypertensive crisis |
| Non-dihydropyridine CCB | diltiazem (PO, IV) | Cartia XT, Cardizem CD, Cardizem LA, Cardizem, Tiazac | - | Atrial fibrilation, hypertension, Coronary artery disease |
| Non-dihydropyridine CCB | verapamil (PO) | Calan SR, Verelan | - | Atrial fibrilation, hypertension, Coronary artery disease |
| Thiazide diuretic | hydrochlorothiazide (PO) | - | - | Hypertension |
| Thiazide-related diuretic | chlorthalidone (PO) | Thalitone | - | Hypertension |
| Dihydropyridine calcium channel blocker (CCB) and Angiotensin-converting enzyme (ACE) inhibitor | amlodipine and benazepril (PO) | Lotrel | Hypertension, heart failure, coronary artery disease | |
| Angiotensin-converting enzyme (ACE) inhibitor and Thiazide diuretic | lisinopril and hydrochlorothiazide (PO) | Zestroretic | - | Hypertension, heart failure, coronary artery disease |
| Angiotensin II receptor blocker (ARB) and Thiazide diuretic | losartan and hydrochlorothiazide (PO) | Hyzaar | - | Hypertension, heart failure, coronary artery disease |
| Angiotensin II receptor blocker (ARB) and Thiazide diuretic | olmesartan and hydrochlorothiazide (PO) | Benicar-HCT | - | Hypertension, heart failure, coronary artery disease |
| Mineralocorticoid receptor antagonist (MRA) | spironolactone (PO) | Aldactone | - | Hypertension, heart failure, ascites |
| Loop diuretic | furosemide (PO, IV) | Lasix | - | Volume overload |
| Loop diuretic | torsemide (PO) | Soaanz | - | Volume overload |
| Beta1-selective beta-blocker | atenolol (PO) | Tenormin | - | |
| Beta1-selective beta-blocker | metoprolol tartrate (PO, IV) | Lopressor | - | |
| Beta1-selective beta-blocker | metoprolol succinate (PO) | Toprol-XL | - | |
| Beta1-selective beta-blocker | nebivolol (PO) | Bystolic | - | |
| Beta1-selective beta-blocker | esmolol (IV) | Brevibloc | - |
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