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CH 15 metabolism
biochem exam 3
| Question | Answer |
|---|---|
| ATP hydrolysis | most thermodynamically favorable and most commonly gets coupled to |
| on phosphate groups the _______ charges make them high energy molecules | negative |
| ATP has a High ______-______ potential | phosphoryl transfer |
| what do your muscles store up and use instead of ATP that has a high phosphoryl potential? | creatine phosphate |
| what happens to ATP when you sprint? | ATP plummets bc it gets used first |
| If your body is not getting enough oxygen what type of metabolism does it shift gears to? | anaerobic metabolism |
| The conversion of ATP to ADP relies on: | motion, active transport, biosynthesis, signal amplification |
| The conversion of ADP back into ATP relies on: oxidation of fuels/molecules or photosynthesis | oxidation of fuels/molecules or photosynthesis |
| What type of reaction does the generation of ATP occur through? | redox reactions |
| How are electrons transported? | via activated carriers |
| NAD+/NADH is a ____ e- carrier | key |
| NADH is the ________ form of NAD+ | reduced. |
| How many e-s does NAD+ pick up ? | 2e-s |
| WHat does NAD+ pick up that keeps it neutral? | H+ proton |
| FAD/FADH2 is a ___ e- carrier. | key |
| What is the reduced form of FAD? | FADH2 |
| How many electrons can FAD carry? and protons? | 2 e-s and 2 H+ |
| NADP+/NADPH is an electron carrier for | reductive biosynthesis |
| The electron donor in most reductive biosyntheses is: | NADPH |
| Coenzyme A is an activated carrier of | Acyl groups |
| The transfer of the acyl group is _________ because the thioester is unstable | exergonic |
| what are most activated carriers derived from? | vitamins |
| Coenzyme A aides in us getting acetyl co A when we leave __________ __________ and it then gets taken to the _______ _______ _______ for the next step | pyruvate oxidation, citric acid cycle |
| Anabolism | builds complex molecules |
| Does anabolism require energy? | Yes |
| Catabolism | breaks down complex molecules |
| Does catabolism require energy? | no |
| what does catabolism have to do with energy? | releases energy |
| fructose 1,6-bisphosphate ---> 2 pyruvate has a net synthesis of _____ NADH and _____ ATP | 2 NADH & 4 ATP |
| glucose ---> 2 lactate results in the net synthesis of _____ NADH and ____ ATP | 0 NADH & 2 ATP |
| Why does the conversion of glucose to 2 lactate result in the net synthesis of 0 NADH? | because glycolysis makes 2 NADH and then lactate dehydrogenase consumes 2 = 0 |
| Why does the conversion of glucose to 2 lactate result in the net synthesis of 2 ATP? | those 2 ATP come from Glycolysis |
| which enzyme responds when blood glucose is elevated and why? | glucokinase has a high Km (low affinity) for glucose so it only becomes active when glucose levels are high |
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