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acute neuro disorder

patho exam 3

QuestionAnswer
central nervous system consists of brain and spinal cord
central nervous system association neurons contained entirely within the CNS, usually relays from afferent to efferent
peripheral nervous system cranial and spinal nerves; afferent (sensory) nerves, efferent (motor) nerves
afferent (sensory) nerves dendrites distal to CNS and axons proximal; conducts impulses from receptor's to the CNS
efferent (motor) nerves dendrites proximal to CNS and axons distal; conducts impulses from the CNS to effectors
somatic nervous system voluntary, conducts impulses from the CNS to skeletal muscles
autonomic nervous system conducts impulses from the CNS to cardiac muscles, smooth muscles, and glands
sympathetic division of the ANS mobilizes body systems during activity
parasympathetic division of the ANS conserves energy, promotes housekeeping functions during rest
neurodevelopment disorders impairments of brain function occurring as brain develops; language, coordination, attention, behavior
why is a brain tumor an acute neurological disorder? development is fast
brain tumors space-occupying lesions that cause increase in intracranial pressure (ICP)
can a benign or malignant brain tumor be life threatening? yes, unless accessible and removable
main problem of brain tumors area where they grow is very compact so tumor increases intracranial pressure
what is a tumor never related to? overgrowth of neurons
what forms the largest category of primary malignant tumors? gliomas
primary malignant tumors rarely metastasize outside of what? the CNS (blood brain barrier)
secondary brain tumor metastasizing from breast or lung tumor
pathophysiology of primary malignant brain tumor usually not well defined, invasive and have irregular projections into adjacent tissue, usually inflammation around the tumor
etiology of primary malignant brain tumor brainstem and cerebellar tumors common in young children; adults: more frequently in the cerebral hemisphere
brain tumors signs and symptoms seizures often a sign; headaches, vomiting, lethargy, irritability, personality and behavior change, possible unilateral facial paralysis, visual problem; do not cause the systemic signs of malignancy
brain tumors treatment may cause damage to normal CNS tissue; surgery if accessible, chemotherapy and radiation
meningitis inflammation of the meninges, may be secondary to other infections
different age groups infected with meningitis are susceptible to what? different causative organisms
meningitis young adults most often due to haemophiles influenzae bacteria (more often in the fall or winter)
meningitis children and young adults neisseria meningitides or meningococci- classic meningitis pathogen
where is neisseria meningitides or meningococci frequently carried? in the nasopharynx of asymptomatic carriers
What is neisseria meningitides or meningococci spread by? respiratory droplets (late winter/ early spring)
meningitis older adults streptococcus pneumonia- major cause
signs and symptoms of meningitis sudden onset is common, severe headache, back pain, photophobia (irritation of optical nerve), nuchal rigidity, kerning sign, brudzinski sign, vomiting, irritability, lethargy, fever and chills with leukocytosis, progressing to stupor or seizures
kerning sign moving patients legs causes movement in the meninges; cause a lot of pain if positive
bruzinski sign moving patients legs causes movement in the meninges; cause a lot of pain if positive
diagnostic test for meningitis examination of CSF (lumbar puncture); identify causative organism
treatment for meningitis aggressive antimicrobial therapy, specific treatment for ICP and seizures, glucocorticoids (stop inflammation), vaccines are available for some types of meningitis
brain abscess usually occurs when bacteria or fungi enter the brain tissue after an infection or severe head injury; pus filled swelling in the brain; usually necrosis of the brain tissue and a surrounding area of edema
where is a brain abscess frequently? localized infection- frequently in the frontal and temporal lobes
where may a brain abscess spread from? an organism in the ear, throat, lung, sinuses
what may a brain abscess result from? septic emboli, acute bacterial endocarditis site of injury or surgery
brain abscess treatment surgical drainage and antimicrobial therapy
encephalitis infection of the parenchymal (nerve or glial cells) or connective tissue of the brain and spinal cord; necrosis and inflammation develop in brain tissue; infection may include meningesc
what may necrosis and inflammation development in brain tissue during encephalitis result in? permanent damage
causes of encephalitis viral infections, bacterial infections, autoimmune disorders, allergic reactions
examples of viral infections that can cause encephalitis herpes simplex virus
examples of bacterial infections that can cause encephalitis lyme disease, tuberculosis
examples of autoimmune disorders that can cause encephalitis multiple sclerosis, lupus
examples of allergic reactions that can cause encephalitis to vaccinations, medications
encephalitis early signs severe headache, stiff neck, lethargy, vomiting, seizures, fever
encephalitis diagnosis imaging tests (ex. CT scan, MRI), CSF analyses
what is tetanus caused by? clostridium tetani
where can tetanus spores survive? in soil (years); wound
what happens in tetanus? exotoxin enters nervous system (effects motor system)
tetanus symptoms tonic muscle spasm, jaw stiffness, difficulty swallowing, stiff neck, headache and skeletal muscle spasm, respiratory failure
what is herpes zosters (shingles) caused by? varicella-zoster virus in adults; years after primary infection of varicella
what does herpes zoster (shingles) usually affect? one cranial nerve or one dermatome
herpes zoster (shingles) symptoms pain, paresthesia, vesicular rash; if antiviral drugs started within 48 hours of onset, pain is significantly reduced; lesion and pain persist for a few weeks
how long may postherpetic pain persist? for months to years in some cases
vaccine for herpes zoster (shingles) chickenpox
head injury may involve skull fracture, hemorrhage and edema, direct injury to brain tissue
mild head injury bruising of the tissue
life threatening head injury destruction of brain tissue/ massive swelling of the brain
concussion minimal brain trauma, reversible interference with brain function
what is a concussion caused by? sudden excessive movement of the brain; mild blow to the head or whiplash type injury
what may follow a concussion? amnesia and headaches
contusion bruising of brain tissue, rupture of small blood vessel (inflammation and edema)
causes of contusion blunt blow to the head- possible residual damage
closed head injury skull is not fractured in injury, brain tissue is injured and blood vessel may be ruptured
when may extensive damage in a closed head injury occur? when head is rotated
open head injuries involved fractures or penetration of the brain
depressed skull fractures involve displacement of a piece of the bone below the levels of the skull, compression of brain tissue, blood supply to area often impaired: pressure to brain
where do basilar fractures occur? at the base of the skull
basilar fractures leakage of CSF through ears or nose is possible
when may a basilar fracture occur? when the forehead hits the windshield
contrecoup injury area of the brain contralateral to the site of direct damage is injured, as brain bounces off the skull; may be secondary to acceleration or deceleration injuries
head injury trauma to brain tissue; cell damage and bleeding lead to inflammation and vasospasm around injury site
what do head injuries cause? loss of function in part of body controlled by the area of the brain
hematoma classified by their location in relation to the meninges
signs and symptoms of head injury focal signs, general signs of increased ICP, seizures, cranial nerve impairment may occur, otorrhea or rhinorrhea, fever (hypothalamus impairment or cranial systemic infection)
focal signs of head injury neurological symptoms that affect a specific area of the brain or nervous system
head injury diagnosis MRI and CT to determine the extent of the brain injury
head injury treatment glucocorticoids agents (decrease edema), antibiotics (reduce infections), surgery (to reduce ICP), oxygen (to protect remaining brain tissue)
Created by: camrynfoster
 

 



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