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Heart failure

QuestionAnswer
Chronotropic drugs affect the rate of the heart's contraction (heart rate and rhythm) by changing electrical impulses that regulate the hearts' rhythm
Inotropic drugs increase the strength of the heart's contractions by altering calcium levels within the cardiac cells
Heart failure Heart cannot pump enough blood to meet the tissue needs of the body
Left sided heart failure manifestations Shortness of breath Moist cough Fluids backup previous to the left ventricle
Right sided heart failure manifestations Peripheral edema venous congestion fluid backs up previous to the right ventricle of the heart (cor pulmonale)
Neurohormonal compensatory mechanisms in heart failure - increased epinephrine and norepinephrine release - RAAS system activation - hypertrophy (remodeling of cardiac tissue)
Cardiotonics digoxin (Lanoxin)
digoxin (Lanoxin) Cardiotonics MOA positive inotropic activity=increased CO negative chronotropic effect= slowed HR allows blood to fill the heart chambers due to slowed HR
digoxin (Lanoxin) ADR Visual disturbances- blurring or yellow halo Digitalis toxicity- GI symptoms Cardiac dysrhythmias
digoxin (Lanoxin) Contraindications **Digitalis toxicity ventricular failure ventricular tachycardia cardiac tamponade restrictive cardiomyopathy AV block/heart block electrolyte imabalnce
digoxin (Lanoxin) Interactions LOTS
digoxin (Lanoxin) Nursing interventions Monitor for CNS effects (visual disturbances) Take apical pulse for 1 full minute before administration administer over 5 min via IV\digoxin immune Fab is antidote for digoxin toxicity
digoxin (Lanoxin) Client education Report nausea, loss of appetite, or vomiting report palpitations monitor HR and report if outside parameters report signs of hypokalemia Risk of toxicity
Sympathomimetics Increase cardiac output in severe HF but only used short-term via IV
dobutamine (Dobutrex) MOA 1. dobutamine activates beta-adrenergic receptors causing a positive inotropic effect 2. increased forces of the heart increased CO 3. Increased CO leads to increased kidney perfusion
CNTD 4. Increased kidney perfusion leads to increased sodium and urine excretion 5. Reduced fluid volume reduces workload of the heart
dobutamine (Dobutrex) ADR Tachycardia Cardiac dysrhythmias anginal pain
dobutamine (Dobutrex) Interventions Monitor ECG Vitals IV only, many incompatibilities, use dedicated line Decreased or discontinue drug for tachyrhythmias correct fluid volume deficit before administration
dobutamine (Dobutrex) Interactions Beta blockers decrease effects
Vasopressor agents used to increase blood pressure in acute hypotension due to cardiogenic, distributive, or septic shock
epinephrine (Adrenalin) MOA non-selective adrenergic agonist that stimulates: - arterial vasoconstriction - positive chronotropic response - positive inotropic response
epinephrine (Adrenalin) Contraindications no contraindications in life-threatening situations
epinephrine (Adrenalin) Interactions interacts with 230 known drugs
epinephrine (Adrenalin) ADR - hypertensive crisis - tissue necrosis and extravasation -tachycardia -seizures -cerebral hemorrhage
epinephrine (Adrenalin) Interventions Central line hypovolemia corrected before infusion monitor apical pulse, BP, output, ecg to regulate dose Immediately report rise in BP monitor extravastion
vasopressin (Antidiuretic Hormone) use for severe hypotension like shock - vasodilatory or hemorrhagic shock that is unresponsive to IV fluids
vasopressin (Antidiuretic Hormone) ADR Increased BP Heart block decreased CO Angina sever peripheral vasoconstriction hemorrhagic shock FVO
vasopressin (Antidiuretic Hormone) contraindications known hypersensitivity
vasopressin (Antidiuretic Hormone) Interactions 295 drugs
Created by: mdedobbe
 

 



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