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| Question | Answer |
|---|---|
| Class of acetaminophen | non-narcotic analgesic anti-pyretic |
| pharm of acetaminophen | inhibits COX2 and peroxidase reaction preventing production of prostaglandins |
| indication for acetaminophen | mild-moderate pain and fever |
| contraindication for acetaminophen | allergic, alcoholism, chronic liver disease, cardiac issues |
| SE of acetaminophen | rare, N/V |
| Adult and Pedi dose for acetaminophen | Adult: 650mg - 975mg PO, 1g IV Pedi: 15mg/kg PO/PR |
| what is dextrose and what is it used for | its a water soluble monosaccharide used to correct hypoglycemia |
| contraindication for dextrose | known hyperglycemia |
| side effects of dextrose | necrosis with extravasation and may worsen existing hyperglycemia |
| Adult and pediatric dose for dextrose | Adult: D50: 25g IV/IO, D10 in 50mL (5g) boluses to max of 250mL (25g) Pediatric: birth -2mo = 5-10mL/kg of D10 Pediatric 2mo-2yr = 2-4 mL/kg of D25 Pediatric >2yr = 1-2mL/kg of D50 |
| class and pharmacodynamics of Solu-Medrol | synthetic glucocorticoid/steroid anti-inflammatory, suppresses immune response |
| indication for solu-medrol | bronchial asthma, COPD, anaphylaxis |
| contraindication for solu-medrol | allergic |
| side effects of solu-medrol | increased BGL, delayed effects not seen in prehospital setting |
| dose of solu-medrol for adults and pediatrics | Ault: 125-250mg IV/IO Pedi: >2mg/kg IV/IO (max 60mg) |
| Terbutaline class and pharmacodynamics | non-selective beta agonist relaxes bronchospasm without as much cardiovascular effects like epi |
| indications for terbutaline | asthma, reversable airway obstruction associated with bronchitis/emphysema, preterm labor |
| contraindications for terbutaline | allergic and <12YO |
| side effects of terbutaline | palps, anxiety, tremulous, HA, dizzy, tachycardia |
| dose of terbutaline | 0.25mg IM |
| class and pharmacodynamics of dexamethasone | synthetic glucocorticoid anti-inflammatory, suppress immune response |
| indication for dexamethasone | bronchial asthma, CPOD, anaphylaxis |
| contraindication for dexamethasone | allergic and (relative) fungal infection |
| side effects of dexamethasone | fluid retention, may delay healing |
| adult and pediatric dose for dexamethasone | Adult: 10mg IV/IO/PO Pedi: 0.5-0.6mg/kg (max 10-16mg) IV/IO/PO |
| pharm of diphenhydramine | H1&H2 histamine blocker |
| indications for diphenhydramine | allergic reaction, anaphylaxis, extrapyramidal reactions, sedation |
| contraindication for diphenhydramine | allergic |
| side effect of diphenhydramine | drowsy, dizzy, loss coordination, blurred vision, hypotension, tachycardia |
| adult and pediatric dose for diphenhydramine | Adult: 25-50mg slow IV/IO/IM Pedi: 1-2mg/kg slow IV/IO/IM max of 50mg |
| pharm of droperidol | dopamine receptor antagonist |
| indication of droperidol | psychosis, chemical restraint of dangerous pts, excited delirium, N/V |
| contraindication of droperidol | parkinsons, acute CNS injury, allergic, prolonged QT, pediatrics |
| side effects of droperidol | extrapyramidal reactions, hypotension, tachycardia, prolong QT, dry mouth, restless, insomnia |
| dose for droperidol | 5-10mg IM/IV/IO slow q x 1 in 5min if needed |
| haloperidol pharm | blocks dopamine receptors, anxiolytic |
| indication of haloperidol | psychosis, chemical restraint of violent and aggressive patients |
| contraindication of haloperidol | hypotension, allergic, prolonged QT, acute CNS injury, parkinsons |
| side effect of haloperidol | EPR, insomnia, restless, dry mouth, hypotension, tachycardia, prolong QT |
| Adult and pedi dose of haloperidol | Adult: <69: 5mg IM max 20mg/day; >69: 2.5mg IM max of 10 Pedi: <6 contraindicated; 6-12: 0.05mg/kg IM (max 2.5mg); 13-18: 2.5-5mg IM |
| class and pharm of flumazenil (romazicon) | benzo antagonist completely blocks GABA/benzo receptor |
| indication for flumazenil | benzo OD |
| contraindication for flumazenil | allergic |
| side effect of flumazenil | opiate W/D, seizure, N/V/D |
| Adult and pedi dose of flumazenil | Adult: 0.2mg IV/IO q 15sec up to 3 doses total Pedi: 0.01mg/kg q 15sec up to 0.05mg/kg total |
| class and pharm of lorazepam | benzo that binds type A GABA increased in chloride influx hyperpolarizing causing sedation |
| indication for lorazepam | anxiety, sedation, seizures, chemical restraint |
| contraindication for lorazepam | allergic |
| side effects of lorazepam | hypotension, sedation, amnesia, respiratory depression, N/V, apnea |
| adult and pedi dose for lorazepam | Adult: 2-4mg IV/IO rate of 2mg/min to max of 8mg Pedi: 0.05-0.1mg/kg over 2-5min max of 4mg |
| class and pharm of nitrous oxide | sedative/anesthetic gas CNS depressant, antagonist to NMDA receptors, agonist to GABA increasing chloride influx |
| indication for nitrous oxide | pain, sedation |
| contraindication for nitrous oxide | COPD, pneumothorax, bowel obstruction, head injury, AMS, EtOH/Drug intoxication, can't follow instructions |
| side effect of nitrous oxide | dizzy, N/V, AMS, HA |
| Dose for nitrous oxide | self admin 50%N2O and 50%O2 |
| pharm of racemic epi | nonselective beta sympathetic agonist |
| indication for racemic epi | croup |
| contraindication for racemic epi | allergic |
| side effect of racemic epi | palps, anxiety, tremors, HA, dizzy, tachy |
| dose for racemic epi | 0.25-0.75 mL of 2.25% diluted in 4mL NS |
| what can you substitute for racemic epi for croup | epi 1:1000: 1mL in 4mL NS epi 1:10,000: 5mL no dilution |
| How does methylene blue treat for nitrate overdose> | It turns the methemoglobin back into its oxygen-carrying form, ferrous oxide |
| indication for methlyene blue | nitrate overdose and CO poisoning |
| contraindication for methylene blue | allergic |
| side effects of methylene blue | serotonin syndrome, dizziness, HA, hemolytic anemia, blue/green discoloration in urine/stool/skin |
| dose for methlyene blue | 1mg/kg IV/IO over 5-10min |
| Pharmacodynamics of phenylephrine | sympathetic agonist almost pure alpha agonist |
| indication for phenylephrine | normovolemic hypotension, septic shock, spinal shock |
| contraindication for phenylephrine | cariogenic shock |
| side effects of phenylephrine | palps, anxiety, tremors, HA, dizziness, worsened ischemia, reflex bradycardia |
| Dose for phenylephrine | 100-180mcg/min (0.5-2mcg/kg/min) IV |