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Diuretics cardio 1

Cardio 1

QuestionAnswer
Diuretics are indicated for ..? Edema caused by - CHF - Endocrine disturbances - Kidney and liver disease - FVO
Loop diuretics furosemide (Lasix)
Loop diuretics furosemide Lasix MOA Blocks the reabsorption of sodium and chloride in the ascending loop of Henle promotes the excretion of urine, sodium, chloride, and potassium
furosemide Lasix ADR electrolyte imbalances- Hypokalemia Dehydration and volume depletion Hypotension and orthostasis Ototoxicity Increased uric acid levels- risk for acute gout flare up
furosemide Lasix INTERACTIONS ACE inhibitors and ARB increase risk of hypotension (angiotensin receptor blockers = ARBs)
furosemide Lasix Client instructions Eat high potassium foods restrict sodium Take in morning (nocturia) protect skin due to photosensisitivy
furosemide Lasix Administration and Interventions IV: give slowly (1-2 minutes) to reduce ototoxicity risk Monitor daily weights at same time strict I and O falls risk (orthostasis)
Thiazide and related diuretics HCTZ- hydrochlorothiazide (Apo-hydro, Aquazide, BPZide, Dichlotride, Esidrex, Hydrochlorot, Hydrodiuril, Hydrosaluric, Hypothiazid, Microzide, Oretic)
hydrochlorothiazide MOA Inhibits the reabsorption of sodium and chloride in the early distal tubule of nephron Excretes water, sodium, chloride, and potassium
hydrochlorothiazide treats *first drug given in treatment of hypotension
hydrochlorothiazide ADR -Volume depletion (dehydration) -Electrolyte imbalance- hypokalemia, hypochloremia, hyponatremia - Increased uric acid associated with gouty arthritis flare ups
hydrochlorothiazide Interactions and contraindications Digoxin toxicity with hypokalemia or hypomagnesemia NSAIDS reduce effectiveness Electrolyte imbalance Renal/hepatic impairment
hydrochlorothiazide Client instructions Report weight change of more than 3 pounds in 1 day Take with food or milk to reduce GI effects
hydrochlorothiazide Nursing interventions Daily weights at same time Give last dose by 3pm to avoid nocturia
Potassium-sparing diuretics spironolactone Aldactone
spironolactone Aldactone potassium sparing diuretics MOA Blocks the reabsorption of sodium in the collecting tubules, increases sodium and water in the urine, reduces the excretion of potassium **aldosterone antagonist
spironolactone Aldactone ADR Hyperkalemia Endocrine effects female: voice drop, abnormal hair growth, menstrual irregularities Endocrine effects male: gynemastia and impotence
spironolactone Interactions and contraindications ACE inhibitors ARBs direct renin blockers potassium supplements alcohol, nitrates, and other antihypertensives hyperkalemia contraindication
spironolactone Aldactone Client education Report palpitations, irregular pulse, and other signs of hyperkalemia Avoid potassium and potassium supplements and salt substitutes Take with food to increase absorption
Created by: mdedobbe
 

 



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