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Poisons

PoisonHospital referal doseNotes
Colchicine Child: Adult: >0.1 mg/kg Multiorgan failure - early GI issues, delayed organ effects, no antidote
Baclofen Child: Adult: >200 mg (drug naïve) Prolonged sedation, coma mimicking brain death
Clonidine Child: >5 to 10 micrograms/kg (depends on time of day) Adult: CNS depression CV effects (persistent bradycardia)
Sulfonylureas "Gli..." Gliclazide Glibenclamide Glimepiride Glipizide Child: 1 tablet Adult: Delayed onset profound hypoglycemia (18 hours for paeds)
Metformin Child: >1700 mg or >100 mg/kg Adult: 20 grams??? MALA (Metformin-Associated Lactic Acidosis) >20 g DSP (CT). Lactic acidosis main issue, does not cause hypoglycemia
Insulin Child: any error Adult: any long acting, or >2x short acting, or night time sweet drink + carbohydrates Depot effect in large doses
Created by: duncanpickup
 

 



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