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7 - BB Learning
| Term | Definition |
|---|---|
| Learning / Memory | Learning - Change in Behaviour from Experience (acquiring knowledge) Knowledge AFFECTS Behaviour |
| Memory | RETENTION Learned Information |
| Learning | CHANGE IN BEHAVIOUR (EXPERIENCE) |
| Memory | RETENTION OF LEARNED INFORMATION |
| MEMORY TYPES (2) | Declarative Non Declarative |
| Declarative Memory Type | Conscious YES Brain areas - Medial Temporal Lobe (Hippocampus) Example - Facts, Events, Names |
| Non Declarative Memory Type | Conscious NO Brain areas - Cerebellum (movement), Striatum (Habits), Amygdala (emotions) Cerebellum, Striatum, Amygdala (emotions) Skills like riding a bike |
| LEARNING TYPES (2) | Non Associative Associative |
| NON ASSOCIATIVE LEARNING TYPE | Habituation, Sensitisation Response changes to repeated stimulus |
| ASSOCIATIVE Learning Type | Classical and Instrumental Conditioning Associations between stimuli/events |
| Memory Systems | Short term/Working Memory Long Term Memory |
| Short term/Working Memory | 7 items, Easily disrupted, Prefrontal Cortex |
| Long Term Memory | More Stable, May not need STM first Emotional/Spaced practice help |
| Neuroplasticity | Brain changes with Experience |
| Learning | Behaviour change with EXPERIENCE |
| Behaviour Change | BRAIN |
| NeuroGENESIS | NEW NEURONS (Dentate Gyrus - HIPPOCAMPUS) |
| HIPPOCAMPUS | GENESIS - THINK OF HIPPOPOTAMUS EVOLVING |
| Dendritic branching/pruning | More Input More Branches |
| Synaptic Plasticity | Strengthening or Weakening of Synapses |
| Synaptic Plasticity involves | LTP or LTD |
| LTP LONG TERM POTENTIATION SYNAPSES | STRENGTHENS SYNAPSE more EPSPs Better Memory |
| LONG TERM DEPRESSION | WEAKENS SYNAPSE "Unlearns" incorrect info |
| Key terms | Hebb - Neurons that fire together wire together FIRE TOGETHER = WIRE TOGETHER Synaptic specifity, cooperativity, associativity: synapses active together are strengthened TOGETHER = STRENGTHENED NEURONS WIRE SYNAPSES STRENGTHEN |
| Molecular Mechanisms | GLUtamate Receptors AMPA: Initial EPSP NMDA: Needs depolarisation (Mg2 block removed) allow Ca2+ entry -> triggers LTP |
| AMPA | Initial EPSP |
| Depolarisation | -> triggers LTP |
| High Frequency firing | LTP (via CaMKII, PKC) |
| Low Frequency firing | LTD (via phosphatases) |
| Neurogenesis | Neural Stem Cells (Subependyma) SUBEPENDYMA Triggered by BDNF (Growth Factor) Reduced in depression Increased in antidepressants Antidepressents support Neurogenesis |
| Triggered by BDNF (Growth Factor) | Exercise Enriched Environments Exercise and Enriched Environments |
| Key Research Models | Aplysia (Sea Slugs) - Simple Nervous System, study LTP/LTD Morris water maze, Radial arm maze (Animals SPATIAL learning and memory) - SPATIAL and DECLERATIVE memory in RODENTS |
| Spatial memory | Orientation in space Environment |
| HUMAN case studies | Patient HM - Loss of Hippocampus -> Anterograde Amnesia (Can't form new declarative memories) but preserved Procedural Memory |
| Hippocampus | DECLERATIVE MEMORIES |
| Anterograde Amnesia | No Hippocampus No Declarative Memories Procedural Memory intact |
| Alzheimer's Disease | Loss of Acetylcholine (ACh) Memory Loss Personality Changes Cognitive Decline |
| Alzheimer's Disease is treated | With Cholinergic Drugs |
| Working Memory | Involves Prefrontal Cortex Tested by Delayed Response Task Holds/Manipulates info short term (Eg mental arithmetic) |
| Working Memory Broken Down | Prefrontal Cortex Delayed Response Task Holds info short term Mental arithmetic |
| WM | How your memory works in day to day situations |