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Chapter 39
Female Reproductive System
| Question | Answer |
|---|---|
| Dysmemorrhea | painful menstruation Primary - 6-12mo after menarche secondary - after 25yo caused by pelvic pathology (endo, adenomyosis, PID, IUD, fibroids or cysts - IBD/IBS - pain radiates to back or thighs |
| PMS / ovarian cycle syndrome | symptoms occur between ovulation & menstruation |
| PMDD | abnormal serotonin responses to change in estrogen levels |
| infertility | primary - inability to conceive a child at least a year secondary - inability to conceive after having conceived or to maintain pregnancy long enough to deliver viable infant |
| factors to infertility - females | problems with ovulation abnormality in endometrium, uterus malformation, pathway between cervix and fallopian tube tumors in reproductive tract |
| factors to infertility - males | problems with sperm abnormal ejaculation, erections, and seminal fluid |
| clomiphene (clomid) | stimulates FSH & LH production |
| assisted reproductive therapy (ART) | IVF-ET - In vitro fertilization and embryo transfer ZIFT - zygote intrafallopian transfer TDI - therapeutic donor insemination intracytoplasmic sperm injection |
| dyspareunia | painful sexual relations uterine prolapse |
| denosumab (prolia) | increase bone density in treatment of osteoporosis |
| cystocele | bladder prolapse - urinary incontinence |
| rectocele | rectum prolapse - constipation, soiling or painful defecation |
| enterocele | bowel prolapse |
| PCOS | associated with obesity and insulin resistance - high testosterone & LH, low FSH |
| Amenorrhea | causes: defects in endocrine, chronic disease, extreme weight loss or obesity, emotional disturbances drug side effect, excessive exercise, poor nutrition |
| metrorrhagia | bleeding between menstrual periods due to leiomyomas, uterine polyps, trauma, malignancy, infection |
| mittle staining | normal spotting in times of ovulation |
| Menorrhagia | excessive menstrual bleeding - hormone imbalance, malignancies, fibroids, infections, some drugs von willebrand (factor VIII dysfunction ) Treat: tranexamic acid - nonhormonal |
| Leuprolide (lupron) naferelin (synarel) | used for leiomyoma and endometriosis - limit to 6mo period |
| salpingo-oophorectomy panhystorectomy | removal of uterus, fallopian tubes and ovaries (cervical cancer) |
| tamoxifen | used to prevent recurrent breast cancer |