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CAPP Unit 5

Cell Cycle & Communication

TermDefinition
apoptosis self-destruction of a cell
autocrine a type os cell signaling where the signaling cell and target cell are the same cell
cell-to-cell communication type of cell signaling where ligands travel between cells that are physically touching - ligands travel through gap junctions or plasmodesmata
centromere the connection point of two sister chromatids
endocrine a type of cell signaling where the ligand enters the blood stream and travels to several types of target cells
paracrine a type of cell signaling where the ligand travels a short distance through the extracellular matrix - cells are not touching, ligands do not enter the bloodstream
diploid a cell that has two copies of every chromosome, one from mom and one from dad - in humans 46
G zero Phase a resting phase that cells enter when not dividing - can be permanent or temporary
anaphase the phase in mitosis where chromatids separate, begin to move to opposite ends of the cell, and are again called chromosomes
binary fission type of cell division in bacteria that is similar to mitosis
cell cycle the life cycle of a cell that goes through growth, synthesis, and division of the DNA and cell into two daughter cells
checkpoint a place in the cell cycle where chemical regulators check that the cell is healthy and DNA was replicated correctly
centriole cell organelle that creates the spindle fibers to arrange and separate chromatids during mitosis
cyclin a type of protein that regulates the cell cycle
p53 a negative regulator, p53 stops the cell from dividing if mutations in DNA are detected
G1 phase first gap or growth phase of interphases, the cell grows large in size, carries out cell processes, and makes more organelles
haploid a cell that has one copy of each chromosome, sperm and egg cells are examples
histone a type of protein that acts as a spool for DNA to wind around when chromatin condenses into chromosomes
homologous chromosome one of a pair of similar chromosomes, containing the same genes though with slight variations. One homologous chromosome is inherited from mom, the other from dad
interphase the longest phase of the cell cycle, contains G1, S, and G2
metaphase stage in mitosis where the chromosomes line up in the middle of the cell
gamete a sex cell
mitotic spindle the fibers created by the centrioles that position, move, and separate the sister chromatids during mitosis
oncogene a gene that creates a protein that causes cancer, either by failing to stop a defective cell from dividing, or by encouraging the cell to divide uncontrollably
S phase synthesis phase, occurs during interphase, it is when the DNA is replicated so that there are 2 complete copies
telophase stage in mitosis where the chromosome sets are at opposite ends of the cell, and the nuclear envelopes reform
prophase the first stage in mitosis, where DNA (chromatin) condenses to form visible chromosomes, and the nuclear envelope disappears.
transduction the carrying of a cell signal from the receptor to the responding enzyme, protein, or DNA
quorum sensing a type of cell signaling in bacteria where bacteria cells respond to the population density surrounding them
G2 phase the second gap or growth phase in interphase - the cell grows a bit more, and creates proteins and supplies needed for mitosis
gene a section of DNA that codes for a specific protein
genome all of the genes that a particular species of organisms has
 



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