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Haemotology pt 1
| Question | Answer |
|---|---|
| Haematology | The study of the normal and pathologic aspects of blood and its elements. |
| Haematopoiesis | The continuous formation of blood cells to replace those lost through aging or injury. |
| Haemoglobin | The iron-containing pigment that gives red blood cells their red colour and carries oxygen. |
| B Lymphocytes | Lymphocytes that produce and secrete antibodies, crucial for humoral immunity. |
| Adult Haemoglobin (HbA) | The predominant form of haemoglobin in adults, composed of 2 alpha and 2 beta chains. |
| Natural Killer (NK) Cells | Large granular lymphocytes involved in innate immunity, recognizing and killing infected or tumor cells. |
| Monocytes | Large circulating leukocytes that differentiate into tissue macrophages, involved in phagocytosis and antigen presentation. |
| Haematopoietic Stem Cells (HSCs) | Quiescent, self-renewing cells that give rise to all blood cell lineages. |
| Basophils | The rarest circulating leukocyte, involved in anaphylactic hypersensitivity and inflammatory reactions. |
| Platelets (Thrombocytes) | Discoid, anucleate cell fragments that play a primary role in hemostasis and are involved in early atherosclerosis. |
| Lymphocytes | Small leukocytes central to adaptive immunity, distinguished by surface receptors that recognize specific antigens. |
| Leukocytes | The least numerous blood cells, crucial for immune defense, divided into granulocytes and mononuclear cells. |
| Peripheral Blood | Consists of three cellular components suspended in plasma: red cells, white cells, and platelets. |
| Eosinophils | Leukocytes that play a role in defense against parasitic infestations and modulation of allergic responses. |
| Erythropoiesis | The process of generating new erythrocytes from haematopoietic stem cells, regulated by erythropoietin. |
| Plasma | The pale-yellow aqueous solution that suspends blood cells, comprising about 60% of total blood volume. |
| T Lymphocytes | Lymphocytes involved in cell-mediated immunity, including helper and cytotoxic T cells. |
| Phagocytosis | The cellular process by which cells engulf and digest foreign particles or microorganisms. |
| Fetal Haemoglobin (HbF) | A type of haemoglobin present from 10 weeks gestation to term, composed of 2 alpha and 2 gamma chains. |
| Granulocytes | A category of leukocytes including neutrophils, eosinophils, and basophils, characterized by cytoplasmic granules. |
| Hypoxia | A condition in which tissues are deprived of adequate oxygen supply, stimulating erythropoietin production. |
| Reticulocyte | An immature red blood cell that has been released from the bone marrow and matures into a full red blood cell within 1-2 days. |
| Neutrophils | The most abundant leukocyte in adults, primarily involved in non-specific defense against bacterial and fungal infections. |
| Erythropoietin (EPO) | A hormone primarily produced by the kidneys in response to hypoxia, stimulating red cell production. |
| Erythrocytes | The most numerous blood cells, specialized for oxygen transport via haemoglobin. |