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Cardiovascular 1&2
| Brand | Generic | Pharmacologic Category | Indication | Essential Knowledge |
|---|---|---|---|---|
| Lotensin | benazepril (PO) | Angiotensin-converting enzyme (ACE) inhibitor | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| Vasotec | enalapril (PO) | Angiotensin-converting enzyme (ACE) inhibitor | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| Prinivil, Zestril | lisinopril (PO) | Angiotensin-converting enzyme (ACE) inhibitor | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| Altace | ramipril (PO) | Angiotensin-converting enzyme (ACE) inhibitor | HTN, HF, CAD | Key Side Effects: cough, hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| Avapro | irbesartan (PO) | Angiotensin II receptor blocker (ARB) | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| Cozaar | losartan (PO) | Angiotensin II receptor blocker (ARB) | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| Benicar | olmesartan (PO) | Angiotensin II receptor blocker (ARB) | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| Diovan | valsartan (PO) | Angiotensin II receptor blocker (ARB) | HTN, HF, CAD | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) |
| Entresto | valsartan and sacubitril (PO) | ARB and neprilysin inhibitor (ARNI) | HF | Key Side Effects: hyperkalemia, angioedema, hypotension US Boxed Warnings: fetal toxicity (CI in pregnancy) Other Notes: Do not use within 36 hours of an ACE inhibitor |
| Norvasc | amlodipine (PO) | Dihydropyridine calcium channel blocker (CCB) | HTN, CAD | Key Side Effects: peripheral edema, hypotension |
| Procardia XL, Adalat CC | nifedipine ER (PO) | Dihydropyridine calcium channel blocker (CCB) | HTN, CAD | Key Side Effects: peripheral edema, hypotension |
| Cardene | nicardipine (PO, IV) | Dihydropyridine calcium channel blocker (CCB) | Hypertensive crisis | Key Side Effects: flushing, headache, peripheral edema, hypotension |
| Cartia XT, Cardizem CD, Cardizem LA, Cardizem, Tiazac | diltiazem (PO, IV) | Non-Dihydropyridine calcium channel blocker (CCB) | AF (rate control), HTN, CAD | Key Side Effects: bradycardia, constipation, peripheral edema, hypotension |
| Calan SR, Verelan | verapamil (PO) | Non-Dihydropyridine calcium channel blocker (CCB) | AF (rate control), HTN, CAD | Key Side Effects: bradycardia, constipation, peripheral edema, hypotension |
| --- | hydrochlorothiazide (PO) | Thiazide diuretic | HTN | Key Side Effects: hypokalemia, hyponatremia, photosensitivity, hypotension |
| Thalitone | chlorthalidone (PO) | Thiazide-related diuretic | HTN | Key Side Effects: hypokalemia, hyponatremia, photosensitivity, hypotension |
| Lotrel | amlodipine and benazepril (PO) | Dihydropyridine calcium channel blocker (CCB) and Angiotensin-converting enzyme (ACE) inhibitor | HTN, HF, CAD | |
| Zestoretic | lisinopril and hydrochlorothiazide (PO) | ACE inhibitor and Thiazide diuretic | HTN, HF, CAD | |
| Hyzaar | losartan and hydrochlorothiazide (PO) | Angiotensin II receptor blocker (ARB) and Thiazide diuretic | HTN, HF, CAD | |
| Benicar-HCT | olmesartan and hydrochlorothiazide (PO) | Angiotensin II receptor blocker (ARB) and Thiazide diuretic | HTN, HF, CAD | |
| Diovan-HCT | valsartan and hydrochlorothiazide (PO) | Angiotensin II receptor blocker (ARB) and Thiazide diuretic | HTN, HF, CAD | |
| Aldactone | spironolactone (PO) | Mineralocorticoid receptor antagonist (MRA) | HTN, HF, ascites | Key Side Effects: gynecomastia, hyperkalemia, hypotension |
| Lasix | furosemide (PO) | Loop diuretic | Volume overload | ey Side Effects: hypokalemia, hypomagnesemia, hyponatremia, hypotension US Boxed Warnings: fluid and electrolyte loss |
| Soaanz | torsemide (PO) | Loop diuretic | Volume overload | Key Side Effects: hypokalemia, hypomagnesemia, hyponatremia, hypotension |
| Tenormin | atenolol (PO) | Beta 1- selective beta-blocker | AF (rate control), CAD, HTN | Key Side Effects: bradycardia, hypotension US Boxed Warnings: avoid abrupt discontinuation Other Notes: masks symptoms of hypoglycemia |
| Lopressor | metoprolol tartrate (PO) | Beta 1- selective beta-blocker | AF (rate control), CAD, HTN | Key Side Effects: bradycardia, hypotension US Boxed Warnings: avoid abrupt discontinuation Other Notes: masks symptoms of hypoglycemia |
| Toprol-XL | metoprolol succinate (PO) | Beta 1- selective beta-blocker | HF, AF (rate control), CAD, HTN | Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia |
| Bystolic | nebivolol (PO) | Beta 1- selective beta-blocker | HTN | Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia |
| Brevibloc | esmolol (IV) | Beta 1- selective beta-blocker | HTN, AF (rate control), hypertensive emergency | Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia; CI with pulmonary hypertension |
| Coreg, Coreg CR | carvedilol (PO) | Non-selective beta-blocker and alpha 1 blocker | HF, AF (rate control), CAD, HTN | Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia |
| Trandate | labetalol (PO) | Non-selective beta-blocker and alpha 1 blocker | PO: HTN, IV: hypertensive crisis | Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia |
| Inderal LA, Inderal XL | propranolol (PO) | Non-selective beta-blocker | HTN, CAD, migraine prophylaxis | Key Side Effects: bradycardia, hypotension Other Notes: masks symptoms of hypoglycemia |
| PO: Catapres Transdermal: Catapres-TTS | clonidine (PO) | Alpha 2 agonist | HTN, ADHD | Key Side Effects: xerostomia, drowsiness, contact dermatitis (transdermal), hypotension US Boxed Warnings: avoid epidural use Other Notes: do not discontinue abruptly; taper to reduce rebound HTN |
| Apresoline | hydralazine (PO) | Direct arterial vasodilator | HTN | Key Side Effects: hypotension, drug-induced lupus-like syndrome Other Notes: CI in CAD |
| Adrenalin, EpiPen | epinephrine (IV,IM,SQ) | Beta 1, beta 2, and alpha 1 agonist | Advanced cardiac life support, shock, anaphylaxis, bradycardia | Key Side Effects: tachyarrhythmias, peripheral ischemia, hyperglycemia |
| Levophed | norepinephrine (IV) | Alpha 1 agonist (predominantly), beta 1 and beta 2 agonist | Shock | Key Side Effects: tachyarrhythmias, peripheral ischemia US Boxed Warning: extravasation (central line administration preferred) |