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Trauma
meds not including top 10
| Question | Answer |
|---|---|
| how does etomidate work | non-barbiturate/benzo sedative that interacts with GABA receptors causing general anesthesia and analgesia |
| indication for etomidate | sedation, DSI |
| contraindication for etomidate | allergic |
| adverse reaction to etomidate | laryngospasm, reparatory depression, suppress cortisol, not good for long-term head injury patients, mycolinc jerks |
| dose for adults and pedi for etomidate max for pedi and duration | adult & pedi: 0.2-0.4mg/kg 1 dose only max 20mg pedi duration 5-10min |
| how does hydroxocobalamin work | binds cyanide forming nontoxic cyanocobalamin (vitB12) preventing toxic effects |
| indication for hydroxocobalamin | suspected cyanide poisoning |
| contraindication for hydroxocobalamin | allergic |
| adverse effects of hydroxocobalamin | hypertension, anaphylaxis, angioedema, N/V/D, and red urine up to 2-5wks |
| dose for hydroxocobalamin adult and pedi | adult: 5g IV/IO over 15min repeat 5g max of 10g pedi: 70mg/kg IV/IO (max5g) over 15min |
| what class of medication is ibuprofen | NSAID; anti-inflammatory, antipyretic, inhibits prostaglandins |
| indication for ibuprofen | mild-mod pain, fever, inflammation |
| contraindication for ibuprofen | allergic, bronchospasm, angioedema |
| dose for ibuprofen | 200-800mg PO every 6-8hrs max daily 3,200 for adults pedi: 5-10mg/kg PO q 6-8hrs, max 30mg/kg daily |
| side effects of ibuprofen | N/V, GI bleed, allergic reaction |
| action of ketamine | dissociative anesthetic between cortical and limbic system |
| indication for ketamine | sedation/DSI, analgesia |
| adverse reaction to ketamine | severe hallucinations/nightmares |
| dose for ketamine in adults and pedi for DSI and pain management | DSI: 1-2mg/kg onset 30-60sec, duration 10-20min pain management: 0.2 mg/kg IV/IO max single dose of 20mg IM/IN: 0.5mg/kg |
| ketorolac class of medication and how it works | NSAID; inhibits prostaglandins |
| indication for ketorolac | mild-mod pain, fever, inflammation, renal caliculi/kidney stones, fractures |
| contraindication for ketorolac | allergic, bronchospasm, angioedema, children |
| dose for ketorolac | 15-30mg IV, 30-60mg IM |
| side effect of ketorolac | N/V, GI bleed, allergic reaction, dizziness, HA |
| Class of medication for rocuronium and how it works | paralytic; nondepolarizing NMBA competitive antagonist for ACh at NMJ |
| indication and contraindication for rocuronium | indicated for DSI contraindication is allergic |
| adverse effect of rocuronium | hyper/hypotension, skeletal muscle weakness, malignant hyperthermia, apnea |
| adult and pedi dose for rocuronium | adult: 0.6-1.2mg/kg TTP: 60-90sec, DOP: 45-120min pedi: 0.6-1.2mg/kg TTP:30-60sec, DOP 30-60min IV/IO |
| class and action of naloxone | opiate antagonist without agonist properties; reverse respiratory depression from OD |
| indication for naloxone | partial reversal of opiate effects returning respiratory drive from suspected OD |
| contraindication of naloxone | allergic |
| dose of naloxone for pedi and adult | adult: 0.4-2mg IV/IO/IN/IM/nebulizer pedi: 0.1mg/kg up to 2mg |
| side effects of naloxone | F, chills, N/V/D, opiate withdraw, severe CA or seizure |
| what is TXA how does it work | blocks fibrinolysis by binding plasminogen-fibrin interaction |
| indication for TXA | significant hemorrhage |
| contraindication for TXA | SP 3 hours past injury, allergic, suspected thromboembolism, pediatrics |
| side effects of TXA | thromboembolism, musculoskeletal pain |
| dose for TXA | 1g over 10min mixed in 50mL NS bag |
| class and action of Nubain/Nalbuphine | opiate agonist-antagonist; analgesia and sedation binding opiate receptors and has some antagonist properties when not taken orally |
| indication for nubain | mod-severe pain |
| contraindication for nubain | allergic, opiate dependence, respiratory depression, ppediatric |
| Dose for nubain | 10-20mg IV/IO/SQ |
| side effects of nubain | sedation, dizzy, N/V, opiate W/D, caution with renal and liver disease |
| class and action of succinylcholine | depolarizing NMBA agonist to ACh receptors at NMJ causing depolarization and paralysis |
| indication for Succ | DSI |
| contraindication for Succ | hyperK (burns, crush injury), increased ICP, severe trauma, neuromuscular disease |
| adverse effects of Succ | hyperK, bradycardia, prolonged paralysis, increased ICP, muscle fasciculations, malignant hyperthermia |
| dose for adult and pedi for succ | adult: 1-1.5mg/kg IV/IO, TTP 45-60sec DOP 5-10min pedi: 1-1.5mg/kg, TTP 45-60sec, DOP 4-6min |
| class and action of vecuronium | nondepolarizing NMBA, antagonist to ACh receptors at NMJ |
| indication for vecuronium | DSI |
| contraindication for vec | allergic |
| adverse reaction to vec | malignant hyperthermia, skeletal muscle weakness, apnea |
| dose for adult and pedi for vec | adult: 0.1-0.2mg/kg IV/IO, TTP 1-3min, DOP 45-90min pedi: 0.1-0.3mg/kg IV/IO, TTP 1-3min, DOP 30-60min |
| Contraindication for ketamine | allergic and hypertension |