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Enzymes I

Three ways to increase the rate of a chemical reaction? Increase temperature, increase the concentration of reacting substances, and adding a catalyst
Enzymes differ from simple chemical catalyst in their efficiency and specificity
The enzymes name will reflect? the reaction it catalyzes
An enzyme is usually a protein that acts as a catalyst to speed up the reaction without being consumed itself
exception? ribozymes are RNA molecules that act as catalyst
Most enzymes are high specific for ? their substrates
a characteristic of enzyme is that they are specific
Enzymes have an active site? T or F True
Substrates bind to enzymes at the active site
6 major classes of enzymes oxidoreductases, transferases, hydrolases, lyases, isomerases, ligases
Oxidoreductases Lactate <---> lactatse dehyrogenase <---> Pyruvate NAD to NADH
OIL RIG Oxidation loss of electrons
OIL RIG Reduction gain of electrons
Transferases Kinase catalyzes phosphorylation of molecules Glucose ------ hexokinase ----- glucose-6-phosphate ATP to ADP bottom molecules on right side gets a PO 2, 3
Hydrolases Urea ----- Urease --- CO2 + 2NH3 is with the use of H20
Lyases Pyruvate -----> pyruvate decarboxylase -----> acetaldehyde COO- goes to a CO2 Catalyze group elimination (often to form double bonds) reversible reaction a group may be added
Isomerases Methylmalonyl CoA <-----> methylmalonyl mutase <------> Succinyl CoA -OOC moves to -OOC moving a group or a double bond within the same molecule
Ligases Pyruvate ----> pyruvate carboxylase ----> oxaloacetate CO2 converts to -OOC ATP to ADP + Pi
The height of the activation energy barrier determines the rate of a reaction? T o F True
In a graph where are the reactants and products? The left side is reactants and right side is products
The height of the activation energy barrier is where on a graph is the portion between the bottom line and the top line
Delta G reaction = G products - G reactants True
Exergonic Reaction G < 0 Spontaneous Products under the line
Endergonic G > 0 non-spontaneous products above the line
Enzymes lower the activation energy for a reaction ? T or F True uncatalyzed reaction line on top of catalyzed reaction
what are characteristics of enzymes specificity, speed up reactions, is not consumed in the reaction
what is found at the height of the activate energy barrier? transition state
Created by: sofialorena
 

 



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