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Chapter 13
| Term | Definition |
|---|---|
| erythrocytes | red blood cells transport nutrients and oxygen |
| Thrombocytes | platelets; clot blood |
| Cells blood volume? | 45% |
| Cell's contain ? | Erythrocytes–Leukocytes–Platelets |
| Plasma | Liquid portion of blood; contains Water–salts- nutriets-hormones-vitamins + proteins |
| Basophils | a leukocyte: contain heparin (prevents clotting) and histamine (involved in allergic responses) |
| Eosinophils | phagocytic cells involved in allergic responses and parasitic infections |
| Neutrophils | first line of defence against infection-produced in bone marrown bone marrow- 50-70% of white blood cells |
| Monocytes: | phagocytic cells that become macrophages and digest bacteria and tissue debris |
| Lymphocytes: | Mononuclear leukocyte that produces antibodies/ produced in the bone marrow and classifies as b or t cells and natural killer cells |
| Albumin | plasma protein produced in the liver - Maintains oncotic pressure (prevents fluid from leaking out of blood vessels), transports hormones, drugs, fatty acids |
| Fibrinogen | plasma protein: Converts to fibrin in clot formation / essential for clot forming and healing |
| prothrombin | plasma protein: Converts to thrombin, initiates clotting cascade |
| Globulin | plasma protein: Immune defense (includes immunoglobulins: IgG, IgA, IgM, IgD, IgE) |
| igG | immunoglobulin: Most abundant, crosses placenta |
| Immunoglobin: GAMED | igG, igA, igM, igE, igD |
| TYPE A BLOOD | A antigen and anti-B antibody |
| TYPE B BLOOD | B antigen and anti-A antibody |
| TYPE AB BLOOD | A and B antigens and no antibodies (universal recipient) |
| TYPE O BLOOD | no A or B antigens and both anti-A and anti-B antibodies (universal donor) |
| universal recipient | Type AB |
| universal donor | Type O |
| Coagulation | the process by which blood transforms from a liquid to a gel, forming a fibrin clot to stop bleeding. |
| Warfarin | anticoagulant- bloodthinner |
| fibrin clot | the final product of the coagulation cascade—a mesh-like structure that stops bleeding by sealing injured blood vessels converted from fibrinogen |
| Anticoagulants | blood thinners- prevent or slow down blood clot formation |
| antibody | A specific protein produced by the lymphocytes in response to bacteria, viruses, or other antigens |
| antigen | A substance that stimulates production of an antibody |
| colony-stimulating factor (CSF) | Protein that stimulates growth of white blood cells |
| differentiation | The change in structure and function of a cell as it matures/ cells are changed to specialize for a certain function |
| electrophoresis | A method of separating serum proteins by electrical charge and size |
| erythroblast | An immature red blood cell |
| erythropoietin (EPO) | Hormone secreted by the kidneys that stimulates red blood cell formation |
| hematopoietic stem cell | A cell in bone marrow that develop into all types of blood cells (red, white, platelt) |
| hemoglobin | Blood protein containing iron; carries oxygen in red blood cells |
| hemolysis | Breakdown of red blood cells |
| heparin | An anticoagulant found in blood and tissue cells |
| immunoglobulin | A protein with antibody activity |
| macrophage | a phagocyte, it engulfs foreign material and debris; destroys worn out RBCs |
| megakaryocyte | large bone marrow cells that give rise to platelets |
| myeloblast | Immature bone marrow that gives rise to granulocytes |
| plasmapheresis | a medical procedure that involves removing blood from the body, separating the plasma, and then returning the remaining components back into the bloodstream. a type of apheresis focusing on plasma |
| platelet | A small blood fragment important in clotting |
| thrombin | Enzyme that converts fibrinogen to fibrin during coagulation/ to blood clot |
| -apheresis | removal or separation of a substance from the blood |
| -cytosis | increase in the number of cells |
| -gen | substance that produces or causes |
| -lytic | destruction/break down |
| -oid | resembling/like |
| -osis | abnormal condition/disease |
| -penia | deficiency or lack |
| -phage | cells that eats/engulfs |
| -poiesis | formation/production |
| -stasis | stopping, controlling |
| anemia | A deficiency in erythrocytes or hemoglobin |
| Aplastic anemia | a condition when your bone marrow stops making enough new blood cells |
| Hemolytic anemia | reduction in red cells due to excessive destruction |
| Pernicious anemia: | not enough red blood cells are produced due to a deficiency of vitamin B12/ has large immature megoblasts |
| Sickle cell: | hereditary disorder of abnormal hemoglobin producing sickle shape/ distorted erythrocytes and hemolysis |
| Thalassemia | an inherited defect in the ability to produce hemoglobin, hemoglobin concentration is low |
| Hereditary Spherocytosis | red cells are fragile /an inherited blood disorder where red blood cells are abnormally round and fragile, leading to their premature destruction in the spleen |
| Iron deficiency anemia | the most common type of anemia |
| Hemochromatosis | too much iron in blood leading to organ damage :Liver Gallbladder and Pancreas |
| Polycythemia vera | a type of blood cancer. It causes the bone marrow to make too many red blood cells |
| Hemophilia | excessive bleeding |
| Purpura | occurs when small blood vessels leak blood under the skin leaving small red dots all over |
| Granulocytosis | abnormal increase in granulocytes in the blood |
| Mononucleosis | an infectious disease caused by a herpes virus called Epstein-Barr |
| Multiple myeloma | malignant neoplasm of bone marrow. |
| Apheresis | a medical process that involves drawing blood from a person, separating it into its components, retaining a specific part, and returning the rest to the body |
| poikil/o | varied/ irregular |
| stem cell | An unspecialized (undifferentiated) blood cell that gives rise to mature, specialized form |
| Erythrocyte Sedimentation Rate | a test that measures how quickly red blood cells settle at the bottom of a test tube, which can help detect inflammation in the body. |
| hematocrit | a blood test that measures the percentage of red blood cells in your blood |
| Epstein–Barr virus | also known as human herpesvirus 4 can cause mononucleosis |
| proliferation | the process of cell division and growth resulting in an increase in cells |