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PHO 2
| Generic | Brand | Pharmacologic Category | Common Indication | Key Side Effects | Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|
| hydrocodone and acetaminophen | Lortab, Vicodin, Norco | Opioid and non-opioid combo | Pain | dizziness, drowsiness, N/V, constipation, pruritis, respiratory depression | 3A4 inhibs/inducers affect drug conc. | --- |
| oxycodone and acetaminophen | Percocet, Endocet | Opioid and non-opioid combo | Pain | dizziness, drowsiness, N/V, constipation, pruritis, respiratory depression | 3A4 inhibs/inducers affect drug conc. | --- |
| codeine and acetaminophen | Tylenol w/ Codeine (#3/4) | Opioid and non-opioid combo | Pain | dizziness, drowsiness, N/V, constipation, pruritis, respiratory depression | 3A4/2D6 inhibs/inducers affect drug conc.; respiratory depression and death in children after surgery and are ultra-rapid metabolizers of codeine; hepatotoxicity | --- |
| naloxone | Narcan, Zimhi | Opioid antagonist | Opioid overdose | opioid w/drawal syndrome, pain | --- | --- |
| buprenorphine and naloxone | Suboxone | Opioid use disorder | Opioid use disorder | opioid w/drawal syndrome, constipation, HA, diaphoresis | --- | risk of life-threatening respiratory depression; addition of naloxone reduces parenteral misuse due to w/drawal symptoms |
| ferrous sulfate | FeroSul, SlowFe | Iron supplement | Iron deficiency anemia | N/, stomach upset, constipation, dark and tarry stools | OD leading cause of fatal poisoning in children less than 6 | --- |
| cyanocobalamin | Vitamin B12 | Water soluble vitamin | B12 deficiency | --- | --- | --- |
| folic acid | Vitamin B9 | Water soluble vitamin | Folic acid deficiency | --- | --- | --- |