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Pharm Ch. 9

Pharm Ch. 9 Self Test

QuestionAnswer
What is NOT a benzodiazepine? Zolpidem
Examples of benzodiazepines include: Diazepam, Midazolam, and Triazolam
Benzodiazepines all have pharmacologic actions including: Anxiolytic, anticonvulsant, tx. of insomnia, tx. of alcohol withdrawal, and muscle relaxation
What is NOT a pharmacologic action of benzodiazepines? Analgesic
What is the biggest advantage of using benzodiazepines rather than barbiturates? Safer
What is a major disadvantage of parenteral diazepam? Thrombophlebitis
What is the primary difference between the drug effect of sedation of hypnosis with sedative-hypnotic medications? Dose
Which class of antianxiety agents is most commonly used today? Benzodiazepines
What factors contribute to the effectiveness of the benzodiazepines? Ability to cross the blood-brain barrier, high lipid solubility, and Concentration in adipose tissue
What is the primary mechanism of action of the benzodiazepines? GABA agonist
What is the most common adverse drug effect of the benzodiasepines? Fatigue and drowsiness
Which is the primary benzodiazepine for intravenous use in conscious sedation today? Midazolam
Therapeutic effects of barbiturates Anxiolysis, sedation, sleep induction, anesthesia, anticonvulsant
What is NOT a therapeutic effect of barbiturates? Analgesia
What is the cause of death in barbiturate overdose? Respiratory failure
In which condition is the use of barbiturates absolutely contraindicated? Porphyria
How is the therapeutic use of barbiturates determined? Duration of action
Which anxiolytic is anxioselective? Buspirone
Which drug does NOT act as a GABA agonists used exclusively to treat insomnia? Diazepam (Valium)
Which agent approved by the FDA for treatment of insomnia characterized by difficulty falling asleep is classified as a melatonin receptor agonist? Ramelteon (Rozerem)
What is the site of action for drugs classified as centrally acting muscle relaxants? CNS
What is not a centrally acting muscle relaxant? Ramelteon (Rozerem)
Do benzodiazepines have a wider range of safety than barbiturates? Yes
Are benzodiazepines considered safe for treatment of anxiety in pregnancy? No
Flumazenil (Romazicon) has which action? Benzodiazepine antagonist
Created by: jridder25
 

 



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