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Pharm Ch. 9
Pharm Ch. 9 Self Test
| Question | Answer |
|---|---|
| What is NOT a benzodiazepine? | Zolpidem |
| Examples of benzodiazepines include: | Diazepam, Midazolam, and Triazolam |
| Benzodiazepines all have pharmacologic actions including: | Anxiolytic, anticonvulsant, tx. of insomnia, tx. of alcohol withdrawal, and muscle relaxation |
| What is NOT a pharmacologic action of benzodiazepines? | Analgesic |
| What is the biggest advantage of using benzodiazepines rather than barbiturates? | Safer |
| What is a major disadvantage of parenteral diazepam? | Thrombophlebitis |
| What is the primary difference between the drug effect of sedation of hypnosis with sedative-hypnotic medications? | Dose |
| Which class of antianxiety agents is most commonly used today? | Benzodiazepines |
| What factors contribute to the effectiveness of the benzodiazepines? | Ability to cross the blood-brain barrier, high lipid solubility, and Concentration in adipose tissue |
| What is the primary mechanism of action of the benzodiazepines? | GABA agonist |
| What is the most common adverse drug effect of the benzodiasepines? | Fatigue and drowsiness |
| Which is the primary benzodiazepine for intravenous use in conscious sedation today? | Midazolam |
| Therapeutic effects of barbiturates | Anxiolysis, sedation, sleep induction, anesthesia, anticonvulsant |
| What is NOT a therapeutic effect of barbiturates? | Analgesia |
| What is the cause of death in barbiturate overdose? | Respiratory failure |
| In which condition is the use of barbiturates absolutely contraindicated? | Porphyria |
| How is the therapeutic use of barbiturates determined? | Duration of action |
| Which anxiolytic is anxioselective? | Buspirone |
| Which drug does NOT act as a GABA agonists used exclusively to treat insomnia? | Diazepam (Valium) |
| Which agent approved by the FDA for treatment of insomnia characterized by difficulty falling asleep is classified as a melatonin receptor agonist? | Ramelteon (Rozerem) |
| What is the site of action for drugs classified as centrally acting muscle relaxants? | CNS |
| What is not a centrally acting muscle relaxant? | Ramelteon (Rozerem) |
| Do benzodiazepines have a wider range of safety than barbiturates? | Yes |
| Are benzodiazepines considered safe for treatment of anxiety in pregnancy? | No |
| Flumazenil (Romazicon) has which action? | Benzodiazepine antagonist |