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Resp. Disorders pt 1
patho exam 2
| Question | Answer |
|---|---|
| Structural ways to divide the respiratory tract | upper and lower respiratory tract |
| functional ways to divide the respiratory tract | conducting and respiratory zone |
| upper respiratory tract | from nose to trachea |
| lower respiratory tract | from trachea to alveoli |
| conducting zone | nose to terminal bronchioles |
| respiratory zone | respiratory bronchioles and alveoli |
| Where does gas exchange occur? | in the lungs |
| Where does air come in and out of? | nasal and oral cavity |
| What is the beginning of the lower respiratory tract? | trachea |
| What is the function of the mucus lining of the respiratory tract? | filtrate air |
| What can happen when particles catch on the mucus lining of the trachea? | it can form infection |
| What lines the conducting portion of respiratory system? | respiratory mucosa |
| Why does the respiratory system get so much infection? | because of the respiratory mucosa |
| What does the respiratory system consist of? | an epithelial layer, an areolar layer called the lamina propria |
| Lamina propria | supports the respiratory epithelium |
| What does the lamina propria in the respiratory system contain? | mucous glands that secrete onto epithelial surface |
| What does the lamina propria in the conducting portion of lower respiratory system contain? | smooth muscle cells that encircle lumen of bronchioles |
| How do smooth muscle cells allow air to better penetrate lungs? | by relaxing and contracting |
| What do paranasal sinuses all connect to? | nasal cavity |
| sinusitis | sinus fills with fluid and becomes inflammed |
| laryngopharynx | division between esophagus and trachea |
| nasal cavity | allows for humidification and filtration of air |
| oral cavity | not as many entrances and not as narrow as nasal cavity, more tendency to bring an infection |
| what is cartilage replaced by in bronchioles? | smooth muscle |
| What does smooth muscle allow for in bronchioles? | better opening for air into lungs |
| How many generations do bronchi divide for after entering the lungs? | 20 |
| What allows for gas exchange? | respiratory bronchioles and alveoli |
| How much air is exchanged in the terminal and respiratory bronchioles? | a very small amount |
| Where does most of the gas exchange occur? | alveolus |
| Why does most of the gas exchange occur in the alveolus? | there are many capillaries and they form a thin membrane that allows exchange of O2 and CO2 |
| Inspiration sequence of events | inspiratory muscles contract, thoracic cavity volume increases, lungs are stretched, intrapulmonary volume increases, intrapulmonary pressure drops (to -1mmHg), air flows into lungs until intrapulmonary pressure is 0 |
| How does the diaphragm move during contraction? | inferiorly |
| Expiration sequence of events | inspiratory muscles relax, thoracic cavity volume decreases, elastic lungs recoil passively, intrapulmonary volume decreases, intrapulmonary pressure rises (to +1mmHg), air flows out of lungs down its pressure gradient until intrapulmonary pressure is 0 |
| What does contraction of inspiratory muscles cause? | intrapulmonary pressure to decrease |
| When the volume of the chest increases what happens to the pressure inside? | decreases |
| inspiratory reserve volume | 3100mL- amount of air you can inhale |
| tidal volume | 500mL- amount of air in and out |
| expiratory reserve volume | 1200mL- amount of air released |
| residual volume | 1200mL- amount of air remaining in lungs |
| inspiratory capacity | 3600mL |
| functional residual capacity | 2400mL |
| vital capacity | 4800mL- amount of air inhaled and exhaled |
| total lung capacity | 6000mL- max air inside lungs |
| minute volume | tidal volume times respiratory rate |
| to calculate alveolar ventilation | dead space volume is subtracted from tidal volumes (subtract 150mL) |
| Lung disorders | infections (upper or lower), obstructive lung diseases, restrictive lung diseases, vascular disorders, intrapulmonary disorders (IRDS, ARDS) |
| obstructive lung diseases | block the flow of air into or out of the lungs |
| restrictive lung diseases | the normal expansion of lungs is limited |
| primary viral infection examples | influenza or common cold virus |
| What is the most common cause of infection? | influenza |
| What is the primary viral infection induced by? | virus |
| What happens when the virus attaches to respiratory mucosa? | invades tissues causing necrosis, inflammation, and swelling |
| What does necrosis activate? | the inflammation process |
| What happens after necrosis, inflammation, and swelling during a viral infection? | congestion, obstructive airways |
| Virus spreads along continuous mucosa invading what? | ears, sinuses, bronchi and lungs |
| What is it called when virus invades ears? | Otitis media- inflammation of ears |
| What is it called when virus invades sinuses? | sinusitis |
| What is it called when virus invades the bronchi and lungs? | pneumonia |
| What happens when bacteria penetrate the damaged mucous membranes? | secondary bacterial infection |
| What can a secondary bacterial infection be treated with? | antibiotic |
| Upper respiratory tract infection | acute infection of nose, paranasal sinuses, pharynx, larynx, trachea, or bronchi; range from mild to life-threatening |
| What does it mean if exudate has color in it? | immunologic cells are in it |
| Why is there a high prevalence of upper respiratory tract infections? | large numbers of viruses, ease of transmission, incomplete immunity developed after viral infection, ability of some viruses to mutate |
| Who is at increased risk for upper respiratory tract infection? | very young, very old, immunosuppressed individuals, those with chronic diseases |
| transmission of upper respiratory tract infection | social contact |
| Upper respiratory tract infection pathogenesis | usually viral (initial), primary or secondary bacterial infections |
| Upper respiratory tract infections clinical manifestations | vary depending on location and severity of the infection, and age of the patient, cough and change in mucus are common, rhinorrhea, fever, sore throat, myalgia, malaise |
| rhinorrhea | a profuse, watery discharge from nose |
| upper respiratory tract infection treatment | comfort measures (resting hydration), medications (antibiotics- secondary) |