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biochem ch 12
| Question | Answer |
|---|---|
| describe food and fuel | food-> digestion -> metabolic fuels->anabolism->storage molecules-> metabolic fuels-> rapid catabolism-> ATP |
| Where is glucose stored | as glycogen in the liver |
| how are fatty acids stored | form of triaglycerols in adipocytes |
| What are some intermediates of glucose metabolism | Glyceraldehyde-3-phosphate-> pyruvate-> acetyl-CoA |
| what iis catabolism | involves oxidizing carbon of amino acids ,monosaccharides,fatty acids |
| what are carbons in fatty acids carbohydrates oxidized too | CO2 |
| oxidation | loss of electrons/ loss hydrogen/gain of oxygen |
| reduction | gain of electrons/ gain hydrogen/loss of oxygen |
| what are electrons transferred to | ubiquinone to ubiquinol |
| where are cofactors recycled through | oxidative phosphorylation |
| what are the essential nutrients | histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan,, valine |
| what are the major essential vitamins | folic acid, nicotinamide, pantothenic acid, riboflavin |
| describe metabolism | monomers formed, intermediates with two or three carbons formed, carbons oxidized to co2, electron carriers gain electrons, electron carriers recycled via electron loss, atp n h2o produced. |
| what are metabolic pathways | intracellular , extracellular signals |
| what is intracellular signal | availability of substrate, product , allosteric activators n inhibitors |
| what is extracellular signals | hormones n neurotransmitters, that bind to surface receptors n produce second messengers. steroid hormones bind to intracellular receptors |
| basics of thermodynamics | change of G = change of H-Tchange of S |
| what is gibbs free energy | measure of the free energy of a system. based on H and S |
| whats H, enthalpy | heat content of a system |
| what is S , entropy | measure of the systems disorder or randomness |
| what does free energy change depend on | reactant concentrations |
| what is change of G>0 | not spontaneous, unfavorable, endergonic |
| what is change of G<0 | spontaneous, favorable, expergonic |
| who is unfavorable sometimes coupled with | favorable reactions |
| coupled process | atp is often involved, cleavage phosphoanhydride bonds yells energy to drive unfavorable reactions |
| what drives unfavorable reactions to completion | atp hydrolysis |
| what are the compounds of phosphate hydrolysis | phosphoenolpyruvate, 1,3-bisphosphoglycerate, Atp->AMP+PP1, Atp->ADP+P1 |