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BIO MIDTERM 2

QuestionAnswer
Eukaryotic cell A cell that contains membrane-bound organelles including a nucleus
Plasma membrane A phospholipid bilayer with embedded proteins that separates the cell from its environment
Organelle A membrane-bound structure within a eukaryotic cell with a specific function
Cytoskeleton Network of protein fibers (microfilaments, intermediate filaments, microtubules) that gives the cell shape, support, and movement ability
Microfilament Thin fiber (actin) in the cytoskeleton that supports cell shape and enables movement Powered by ATP. Can disassemble and reassemble quickly, causing movement of cell.
Intermediate filament Intermediate-diameter cytoskeletal filament that helps anchor organelles and maintain structural stability
Microtubule Hollow tube in the cytoskeleton that directs vesicle movement and forms the basis for flagella/cilia (Resisst compression) Can also disassemble and reform quickly.
Myosin Motor protein that “walks” along actin filaments using ATP, often in muscle contraction and intracellular transport
Kinesin Motor protein that travels along microtubules toward the cell periphery, transporting vesicles using ATP
Extracellular matrix Network of proteins (e.g. collagen) and carbohydrates secreted by cells that provides structural support and signaling between cells
Collagen Structural protein abundant in the extracellular matrix that gives tensile strength to tissues
Proteoglycan Large glycoprotein in the ECM with many carbohydrate side chains that helps form a gel-like matrix
Integrin Transmembrane receptor protein that connects ECM outside the cell to the cytoskeleton inside
Metabolism All of the chemical reactions in a cell or organism (including catabolism
Catabolism Metabolic pathways that break down molecules into smaller units and release energy
Anabolism Metabolic pathways that build larger molecules from smaller units and require energy input
Free energy (G) The portion of a system’s energy that can do work under cellular conditions
ΔG (change in free energy) Difference in free energy between reactants and products of a reaction
Activation energy The initial input of energy required to start a chemical reaction
Kinetic energy Energy of motion
Potential energy Stored energy based on position or configuration
Endergonic reaction A reaction that requires an input of energy (ΔG > 0)
Exergonic reaction A reaction that releases free energy (ΔG < 0)
Rough Er Ribosomes attached to cytoplasmic surface. Ribosomes transfer newly synthesized proteins into RER's lumen and eventually transport vesicles outside cell
Smooth ER Continuous with the RER, has few to no ribosomes on its cytoplasmic surface. Synthesizes carbohydrates, lipids, and steroid hormones.
ATP (adenosine triphosphate) Main energy “currency” of the cell, storing energy in phosphate bonds
ADP (adenosine diphosphate) Molecule formed by removing one phosphate from ATP
Substrate The molecule upon which an enzyme acts
Active site The specific region of an enzyme where the substrate binds
Cofactor Inorganic ion (e.g. metal ion) required for some enzyme functions
Coenzyme Organic nonprotein molecule (often vitamin derived) required for enzyme activity
Competitive inhibition When an inhibitor competes with substrate for binding to the enzyme’s active site
Allosteric inhibition When an inhibitor binds to a site other than the active site and changes enzyme shape/activity
Glycolysis Sequence of reactions in cytoplasm that breaks glucose (6C) into two pyruvate (3C), yielding ATP and NADH
Glucose Six-carbon sugar that is the starting substrate in glycolysis
Pyruvate Three-carbon end product of glycolysis that can be further oxidized
Substrate-level phosphorylation Production of ATP by directly transferring a phosphate group to ADP from a phosphorylated intermediate
Acetyl CoA A molecule (acetyl group bound to Coenzyme A) that enters the citric acid cycle
Citric acid cycle (TCA / Krebs cycle) Series of enzyme-catalyzed reactions in mitochondrial matrix that oxidizes acetyl CoA, producing NADH, FADH₂, ATP (or equivalent), and CO₂
Citrate First 6-carbon molecule formed in the citric acid cycle by combining acetyl CoA and oxaloacetate
NADH Reduced form of NAD⁺ that carries electrons to the electron transport chain
FADH₂ Reduced form of FAD that also carries electrons to the electron transport chain
Oxaloacetate Four-carbon compound that combines with acetyl CoA to start the citric acid cycle again
Electron transport chain Series of protein complexes in the inner mitochondrial membrane that transfer electrons and pump H⁺ to build a gradient
Oxidative phosphorylation Process in which ATP is produced using the proton gradient generated by the ETC
Chemiosmosis Movement of protons down their electrochemical gradient through ATP synthase, driving ATP production
ATP synthase Enzyme complex in mitochondrial membrane that synthesizes ATP as protons flow through it
Peroxisomes Small, round organelles enclosed by single membranes that carry out oxidation rxns to break down fatty acids and amino acids. Dextofiy poisons and safetly break down H2O2
Lysosomes Animal Cell specific: breaks down proteins, polysaccharides, lipids, nucleic acids, and acts as a garbage cans/ High pH
Endoplasmic Reticulum Interconnected membrous sacs and tubules that modify proteins and synthesizes lipids in rough Er and Smooth ER respectively
Golgi Apparatus transport vesivles go here to get packaged and distributed. A series of flattened membrous sacs. Side of GA closer to Er is called Cis Face and opposite is Trans.
Lysosomes Use hydrolytic enzymes to destroy pathogens. Fuses with a vesicle that has a pathogen and uses itn hydrolytic enzymes to destory it.
Created by: jinko
 

 



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