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HIV

HIV Pharmacotherapy

BrandGenericSide Effects
Biktarvy Bictegravir + Emtricitabine + TAF Lipid abnormalities, weight gain, increase SCr, hyperpigmentation, HBV exacerbation, polyvalent ions with food, lactic acidosis, increase LFTs
Triumeq Dolutegravir + Abacavir + Lamivudine Organ dysfunction, increase CPK, myalgias, increase MI risk, HLA-B*5701 testing, HBV exacerbation, polyvalent ions with food, lactic acidosis, increase LFTs
Tivicay + Descovy Dolutegravir + Emtricitabine + TAF Organ dysfunction, increase CPK, myalgias, Lipid abnormalities, weight gain, hyperpigmentation, HBV exacerbation, polyvalent ions with food, lactic acidosis, increase LFTs
Tivicay + Truvada Dolutegravir + Emtricitabine + TDF Organ dysfunction, increase CPK, myalgias, AKI, Fanconi syndrome, bone demineralization, hyperpigmentation, HBV exacerbation, polyvalent ions with food, lactic acidosis, increase LFTs
Dovato Dolutegravir + Lamivudine Organ dysfunction, increase CPK, myalgias, HBV exacerbation, polyvalent ions with food
Symtuza (PI) Darunavir + Cobicistat + Emtricitabine + TAF Lipid abnormalities, hyperglycemia, DLP, increase LFTs, lactic acid, CYP3A4 inhibitor, hyperpigmentation, HBV exacerbation, caution w/ sulfa allergy, no anticoagulants, statins, or steroids (except Rosuvastatin, Atorvastatin, Beclomethasone, Warfarin)
Genvoya Elvitegravir + Cobicistat + Emtricitabine + TAF (lactic acidosis, increase LFTs) Proteinuria, AKI, Fanconi syndrome, bone demineralization, CYP3A4 inhibitor, hyperpigmentation, HBV exacerbation, no anticoagulants, statins, or steroids (except Ros/Ator, Beclomethasone, Warfarin), DDI: Ag, Ca, Mg, Fe (2 hr before or 6 hr after)
Stribild Elvitegravir + Cobicistat + Emtricitabine + TDF (lactic acidosis, increase LFTs) Proteinuria, insomnia, AKI, Fanconi, bone demineralization, CYP3A4 inhibitor, hyperpigmentation, HBV exacerbation, no anticoagulants, statins, or steroids (except Ros/Ato, Beclomethasone, Warfarin), DDI: Ag, Ca, Mg, Fe (2 hr before or 6 hr after)
Odefsey Rilpivirine + Emtricitabine + TAF (lactic acidosis, increase LFTs) Depression, do not use with PPIs, take with food, increase SCr, Lipid abnormalities, hyperpigmentation, HBV exacerbation, SJS/TEN, hepatotoxic, do not use if VL > 100k and/or CD4 < 200
Complera Rilpivirine + Emtricitabine + TDF (lactic acidosis, increase LFTs) Depression, do not take with PPIs, take with food, SJS/TEN, hepatotoxic, increase SCr, AKI, Fanconi syndrome, bone demineralization, hyperpigmentation, HBV exacerbation, do not use if VL > 100k and/or CD4 < 200
Atripla Efavirenz + Emtricitabine + TDF (lactic acidosis, increase LFTs) Depression, SJS/TEN, suicidal ideation, abnormal dreams, increases cholesterol & TG, AKI, Fanconi, bone demineralization, hepatotoxic, hyperpigmentation, HBV exacerbation, take on empty stomach to decrease ADR
Delstrigo Doravirine + Lamivudine + TDF (lactic acidosis, increase LFTs) SJS/TEN, hepatotoxic, AKI, Fanconi syndrome, bone demineralization, HBV exacerbation
Created by: jolikes2play
 

 



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