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DNA

TermDefinition
DNA A double-stranded molecule that carries the genetic instructions for life.
Nucleotide The building block of DNA and RNA, consisting of a sugar, phosphate group, and nitrogen base.
Deoxyribose Sugar The sugar found in DNA nucleotides, forming part of the DNA backbone.
Ribose Sugar The sugar found in RNA nucleotides, forming part of the RNA backbone.
Phosphate Group A molecule that links sugars together in DNA and RNA, forming the backbone.
Nitrogen Bases Molecules that make up the “rungs” of the DNA ladder and code for genetic information.
Adenine (A) A nitrogen base in DNA and RNA that pairs with Thymine (DNA) or Uracil (RNA).
Thymine (T) A nitrogen base found only in DNA that pairs with Adenine.
Cytosine (C) A nitrogen base found in DNA and RNA that pairs with Guanine.
Guanine (G) A nitrogen base found in DNA and RNA that pairs with Cytosine.
Uracil (U) A nitrogen base found only in RNA that replaces Thymine and pairs with Adenine.
Double Helix The twisted-ladder shape of DNA that provides structural stability.
Complementary Base Pairing The rule that Adenine pairs with Thymine (or Uracil) and Cytosine pairs with Guanine, ensuring accurate replication and transcription.
DNA Replication The process by which DNA makes an exact copy of itself before cell division.
Helicase An enzyme that unwinds and separates the DNA strands during replication.
DNA Polymerase An enzyme that adds complementary nucleotides to form the new DNA strand.
Ligase An enzyme that connects fragments of DNA, sealing the sugar-phosphate backbone.
RNA A single-stranded nucleic acid involved in protein synthesis.
mRNA (Messenger RNA) RNA that carries genetic code from DNA to the ribosome.
tRNA (Transfer RNA) RNA that carries amino acids to the ribosome and matches anticodons to mRNA codons.
rRNA (Ribosomal RNA) RNA that combines with proteins to form ribosomes, the site of protein synthesis.
Transcription The process in which DNA is transcribed into mRNA in the nucleus.
Translation The process in which mRNA is decoded into a protein (amino acid chain) at the ribosome.
Codon A sequence of three mRNA bases that codes for one amino acid.
Anticodon A sequence of three bases on tRNA complementary to the mRNA codon.
Amino Acid The building block of proteins, linked together to form polypeptides.
Polypeptide / Protein A long chain of amino acids that performs cellular functions.
Ribosome Cellular structure made of rRNA and proteins where mRNA is translated into protein.
Gene A segment of DNA that codes for a specific protein, determining traits and functions.
Mutation A change in the DNA sequence that may alter the protein or have no effect.
Leading Strand The DNA strand that is synthesized continuously in the 5’ → 3’ direction toward the replication fork.
Lagging Strand The DNA strand that is synthesized discontinuously in short fragments (Okazaki fragments) away from the replication fork.
Helicase An enzyme that unwinds and separates the two DNA strands at the replication fork.
RNA Primer A short segment of RNA that provides a starting point for DNA synthesis.
DNA Polymerase An enzyme that adds complementary nucleotides to the new DNA strand and proofreads for errors.
Ligase An enzyme that joins Okazaki fragments on the lagging strand by sealing the sugar-phosphate backbone.
Primase An enzyme that synthesizes the RNA primer needed for DNA polymerase to begin replication.
Topoisomerase An enzyme that relieves tension in the DNA helix ahead of the replication fork by preventing supercoiling.
Single-Strand Binding Proteins (SSB) Proteins that bind to single-stranded DNA to prevent it from re-annealing during replication.
mRNA (Messenger RNA) RNA that carries the genetic code from DNA to the ribosome.
tRNA (Transfer RNA) RNA that carries specific amino acids to the ribosome and matches anticodons to mRNA codons.
rRNA (Ribosomal RNA) RNA that combines with proteins to form ribosomes, the site of protein synthesis.
Transcription The process of copying DNA into mRNA in the nucleus.
Translation The process of decoding mRNA into a polypeptide (protein) at the ribosome.
Codon A sequence of three mRNA nucleotides that codes for a specific amino acid.
Anticodon A sequence of three nucleotides on tRNA complementary to the mRNA codon.
Amino Acid The building block of proteins, linked together in a polypeptide chain.
Polypeptide / Protein A chain of amino acids that folds into a functional protein.
Ribosome The molecular machine that facilitates translation of mRNA into protein.
Created by: Poorani10
 

 



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