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BIOL 1101 Exam Two
Pre-Class Notes, Sept 24
| Question | Answer |
|---|---|
| What are the three types of fibers within protein fibers of the cytoskeleton | microfillaments, intermediate filaments, and microtubulus |
| What is the function of microfilaments | function in cellular movements |
| What are microfilaments made out of | comprised of 2 globular protein strands called actin |
| What is ATP role in microfilaments | powers actin to assemble into filamentous form, track for movement of motor protein called myosin |
| What are intermediate filaments | several strands wound together |
| What is the function of intermediate filaments | no role in cellular movement, only structural; tension allows cell to maintain shape |
| What are microtubules mad of | Alpha-tubulin and Beta-tubulin |
| What are the functions of microtubules | help cell resist compression, provide track for vesicles to move through cell, put replicating chromosomes on opposite ends of the dividing cell |
| What are flagella | hairlike structures that extend from plasma membrane, allow for entire cell to move |
| What is included in the extracellular matrix | Collagen protein, protoglycans |
| How does the matrix hold cells together | Cells have protein receptors on plasma membrane, when molecule binds to receptor, changes receptor's structure, changes microfilament conformation, induces chemical change to turn on/off DNA transcription, changes proteins made |
| What is an example of cell signaling in the extracellular matrix | blood clotting, when cells lining a blood vessel are damages, they display a protein receptor |
| How does endocytosis work | Cell's plasma membrane invaginates, forms a pocket around target particle, pocket pinches off, creating new intracellular vesicle within membrne |
| What is phagocytosis | When cell takes in large particle |
| How does phagocytosis work | Clathrin protein coats plasma membrane that faces inward, extends from cell and surrounds particle, clarthin disengages from membrane and merges with lysosome, breaks down in endosome, releases digested contents |
| What is pinocytosis | Process where cell takes in molecules and water, which cell needs extracellular fluid for process of pinocytosis |
| How does pinocytosis work | Caveolin protein coats plasma membrane section |
| What is receptor mediated endocytosis | Clathrin attaches to plasma membrane after receptor from cell signaling indicates, polymerizes a coat into vesicle to bring things from outside the cell |
| How does endocytosis of cholestrol work for LDL | Serum cholesterol bound by LDL, floats around the blood stream until it meets with an LDL receptor on the surface of a cell, LDL receptor near clathrin-coat pits, clathrin self-assembles into vesicles and pinches off, vesicle fuses wih endosome, proton pu |
| What are secretory vesicles | Proteins that are packages and delivered for outside the cell |
| What is constitutive exocytosis | Protein from ER migrates to Golgi Apparatus, leave golgi through secretory vesicles, since they have no signaling, there is no control over secretion |
| What happens to vesicles after constitutive exocytosis? | Vesicles contribute new lipids and its own membrane to the cell membrane |
| How does regulated exocytosis work | vesicles containing the product near cell's surface remain there until specific signal arrives that triggers secretion |
| What is an example of regulated exocytosis | pancreatic beta cells regulate exocytosis of secretory vesicles with insulin |