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Cirrhosis and Panc
| Question | Answer |
|---|---|
| Octerotide | Sandostatin - synthetic hormone that effectively stops bleeding by constricting viscera of GI tract and portal-vein inflow. Eso Var. |
| Beta blockers | Propranolol or nadolol are used as a prophylaxis preventative measure for bleeding in esophageal varices - lower BP - Eso Var |
| Nitrates | Isosorbide lower portal pressure via vasodilation and portal pressure - used in combo with beta blockers. Esophageal varices. |
| Asthma and Diabetes Patients | Should stick to nitrates as beta blockers will mask hypoglycemia and will lead to bronchospasms |
| Balloon Tamponade | Surgical intervention to pace a special tube that inflates in the esophagus and stomach to compress the varices and stop blood. |
| Sclerotherrapy | A special device that injects a special sclerosant agent that causes the varice to shrink and clot stoppinng the bleeding. |
| Esophageal Banding | Endoscopic variceal band ligation will place tiny rubber bands to cutoff blood flow and prevent bleeding by varices. |
| Lactulose | Osmotic laxative increases osmotic pressure drawing fluid into the colon preventing ammonia absorption - gets released by poo. |
| Neomycin | Broad-spectrum antibiotic given alongside lactulose if that isn't strong enough alone - destroys gut flora that reabsorbs ammonia. |