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Pharm 4
| Question | Answer |
|---|---|
| What is the most common indication for hormone therapy | Menopause |
| What is the goal of hormone replacement therapy for menopause and androgen deficiency | Symptom relief |
| Are you trying to reach with HRT | Not normal levels |
| What are bioidentical hormones | Most similar to the body |
| Are compounded hormones safer than other HRT products | No |
| Are FDA approved bioidentical hormones safer than other HRT | Possibly |
| Which women benefit from the addition of progestin to their estrogen replacement | those with a uterus |
| Is there a preferred age group or time frame that estrogen/progestin HRT is recommended | Age 50-59, and max 5-10years |
| What concerns us about estrogen therapy | Clot risk, HTN,ischemic event |
| What concerns us about adding on progestin therapy | HTN, reduced bone mineral density |
| Do only men get androgen replacement therapy | No women do too |
| What are the potential benefits of hormone replacement therapy | Bone / sexual / decrease all-cause mortality |
| What concerns us about testosterone therapy | Prostate cancer, AKI, A fib |
| What is recommended for prevention of osteoporosis | Vit D 800, Calcium 1200 |
| What non-hormonal options are recommended for hot flashes | SSRI |
| What are options for treatment of osteoporosis | Bisphosphonates |
| What is the role of estrogen in hormonal contraception- prevents what | ovulation |
| What is the role or progestin or progesterone in hormonal contraception- prevents what | Menstruation |
| What typically happens with progestin only pills or IM dep-Provera when there is no drop in progestin | Amenorrhea |
| What are the most effective hormonal contraception option | Implants |
| What is the only contraception option that reduces the risk of STI | Condoms |
| What concerns do we have with estrogen | Cardiac risk,clotting risk |
| Who is estrogen contraindicated in | Cardiac risk, clotting risk, migraine with aura,stroke, older than 35 and smoker, cirrhosis,breast cancer |
| What concerns do we have with progesterone | HTN |
| Who is progesterone contraindicated in | Liver disfunction or any kind of cancer |
| Who should you weigh risk benefit in for progesterone | ASCVD |
| What counseling points are important for progestin only pills | Timing |
| If someone cannot receive hormonal contraception, what is their only option | Copper IUD |
| Which hormonal contraception should we potentially warn an adolescent about using if its <3 years since menarche | DEPO |
| What do you need to confirm prior to initiating contraception for someone | Pregnancy |
| Who may not be ideal candidate for any IUD option | Not sexually active |
| What is the role of estrogen in hormonal contraception- it prevents what | Ovulation |
| What is the role of progestin or progesterone in hormonal contraception- it prevents what | Menstruation |
| What typically happens with progestin only pulls or IM DEPO when there is no drop in progestin | amenorrhea |
| What are the most effective hormonal contraception options | implants |
| What should we say if a woman asks us if shes at increased risk of cancer with hormonal contraception | Increased baseline risk for some |
| Does it matter when you initiate birth control related to someone's menstrual cycle | yes |
| What do they need if its not within 7 days for most options | backup |
| What would you recommend if someone has had unpredicted intercourse within 3-5 days and is asking for emergency contraception | IUD, Morning after |
| What do you recommend if need after 5 days | abortion |
| What do some options require for contraception | prescriptions |
| Is emergency contraception the same thing as using backup contraception's | no |
| Is emergency contraception the same thing as terminating a pregnancy | no |
| What medications do we give to terminate a pregnancy | Mifepristone and Misoprostol |
| What would you do if someone needed to start valproic acid and was on combination OCPs | Switch valproic acid |
| What would you recommend if someone needed to take an antibiotic for 3 days | Backup for 10 days |
| How long does someone have on progestin only pills for a dose to be considered missed | 3h |
| What is the most common indication for hormone replacement therapy | Menopause |
| What is the goal or hormone replacement therapy for menopause and androgen deficiency | Symptom relief |
| What are bioidentical hormones | Most similar to body |
| Are bioidentical hormones compounded | No |
| Are compounded or FDA approved bioidentical hormones safer than other HRT products | No |
| Which women benefit from the addition or progestin to their estrogen replacement | Uterus |
| Who would not benefit from progestin to their estrogen replacement | Those without a uterus |
| Is there a preferred age group or time frame that estrogen/progestin HRT is recommended | 50-59 years for max 5 yr |
| What concerns us about estrogen therapy | |
| What concerns us about progestin therapy | |
| Do only men get androgen replacement therapy | No- women get testosterone for muscle, bones, and sex |
| What are the potential benefits of hormone replacement therapy | Bone/sexual/decrease all cause mortality |
| What concerns us about testosterone therapy | Worsen hypoglycemia |
| Who should not get testosterone therapy | Prostate cancer, AKI, A fb |
| What is recommended for prevention of osteoporosis | Vit D 800, Cal 1200 |
| What non hormonal options are recommended for hot flashes | SSRI |
| What are non supplement options for osteoporosis | Bisphosphonates |
| What are the potential consequences of medication exposure during pregnancy | Teratogenic / Unwanted |
| What are some of the teratogenic medications or medications contraindicated in pregnancy | Ethanol, Warfarin, ACE+ARBS |
| How are medications categorized for use in pregnancy | Now description of risk |
| What happens to a pregnant woman's pharm kinetics that may impact her own medication exposure | Increased volume, clearance, and cardiac output |
| What impacts a drugs ability to reach the embryo/fetus and cause adverse effects | Can it cross the placenta |
| Preferred pain medications in pregnancy | Acetaminophen, opioids, aspirin |
| Contraindicated pain medications in pregnancy | NSAIDS or chronic opioids |
| Antihistamines preferred in pregnancy | Cetirizine and loratadine |
| Antidepressants preferred in pregnancy | SSRIs |
| Antidepressants contraindicated in pregnancy | Fluoxetine pr paroxetine |
| Acne treatment preferred in pregnancy | 1- benzoyl peroxide 2- topical antibiotics |
| Ance treatment contraindicated in pregnancy | retinols or salicylic acid |
| Anticoagulants preferred in pregnancy | Heparin |
| Anticoagulants contraindicated in pregnancy | DOACS and warfarin in category X |
| Antiseizure meds preferred in pregnancy | levetiracetam and lamotrigine |
| Antiseizure meds contraindicated in pregnancy | valproic acid and phenytoin |
| GERD meds preferred in pregnancy | calcium carbonate and H2 |
| GERD meds contraindicated in pregnancy | PPIs until after 12w |
| Constipation meds prefered in pregnancy | Bulk forming agents, probiotics, and polyethylene glycol |
| Nausea/vomiting meds preferred in pregnancy | Vitamin B6, doxy, diphenhydramine, and ginger |
| Nausea/vomiting meds contraindicated in pregnancy | ondansetron prior to second trimester |
| Hypertension meds preferred in pregnancy | Labetalol or Methyldopa |
| Does aspirin need to be avoided in pregnancy like other NSAIDS | no use after 12w for pre-eclampsia |
| What can occur up to 25-30% of infants exposed to SSRI therapy in utero | NAS |
| How to treat infants born with NAS | give breast milk from mom taking med/supportive care |
| What is mom at increased risk for during/after delivery if she is taking SSRI | bleeding |
| What can occur to children exposed to opioids in utero | withdraw/NAS |
| What should you recommend related to caffeine production in pregnancy | Less than 200mg |
| What should you recommend related to alcohol consumption in pregnancy | None |
| What about alcohol consumption during lactation | amount and time dependent |
| How are meds categorized for use while breastfeeding | based on risk/amount |
| What is the standardized way to predict a child's exposure to a medication in breastmilk | RID |
| What is the main concern with antihistamines and breastfeeding | Dries up milk supply |
| What age would you recommend over the counter cough suppressants | 6 |
| What age would you recommend honey for cough | 1 year |
| Wen is it safe for a child to get ibuprophen | 6m |
| What medication do we avoid in those less than 18 yr for fever or pain due to risk of Reye's syndrome | Asprin |
| Why do we care about tetracyclines in kids | Bone denisty, enamel and tooth discoloration |
| Why do we care about fluroquinolones in kids | Kernicterous |
| What is different in pediatric patients compared to adults in regard to their oral absorption of medications | Slower- pH difference and slow motility |
| What impacts topical absorption of medications in children | their skin is more absorbent |
| What impact can bilirubin have on medication distribution | Bind to albumin so meds cannot |
| Meds to avoid in peds with high bili | Sulfonamide |
| What is different about metabolism in pediatric patients | Not fully developed |
| How do you evaluate renal function in pediatric patients | Number of wet diapers- bedside Schwartz |
| What can you utilize to help you evaluate a child's renal function that doesn't involve labs | urine |
| How are medications dosed in pediatrics | weight based and age |
| What's the difference between elixirs and suspensions | Suspensions need shaken |
| What is incredibly important to know when you're prescribing liquid medications | Concentration |
| What things are important about intravenous medication preparation and administration | Needs to be sterile |
| Assess adherence in pediatric patients or anyone for that matter | 4D |
| What is trick about adherence in patients | Dependent on someone else |
| Two main feeding options for infants | Breast feeding and formula |
| What are the differences between ready to feed liquid formula and powder formulas | Sterile, ready to go |
| What are some of the potential benefits of breastmilk over formula | Health benefits |
| What is the impact on mom to breastfeed | Make sure they're okay |
| How should you store breastmilk | fridge |
| How long is formula good for after you mix it | 24h in fridge if hasnt touched baby, 1hr if baby drank |
| How should you clean baby bottles or feeding items | warm water and soap not directly in the sink |
| Is it ever necessary to sanitize feeding products | yes |
| What bacteria are you worried about in bottles | Chromobacter |
| Does a particular type of formula carry a higher risk of carrying bacteria | powder |
| Does it matter what water you mix a bottle with | yes- dont use well water |
| What is the main protein source in formula | cows milk |
| If a baby has confirmed milk intolerance with heme positive stool | eliminate dairy possibly soy |
| Are all hypoallergenic formulas free of dairy or soy | No only 1 has neither |
| What do you need to supplement breast fed babies with that formulas have | Vit D |
| What do most breastfed babies need starting at 4 months | iron |
| Iron for infants | 400 baby or 4,000 for mom |
| What do babies begin around 4-6m | solids |
| Do babies stop drinking breast milk or formula when they begin solids | No not until at least 12m |
| What is the goal with vaccinations | Prevention or lessen the complications |
| Does it matter how vaccinations are sored? | Yes- refrigerated |
| Do you have to record anything about stored vaccinaions | Their temperature |
| What do you have to do after administering a vaccination | Documentation and reporting |
| Do you have to give the family anything when you administer a vaccination | Vaccine info sheet |
| Is reporting and giving information about vaccines optional | No |
| What are common adverse effects from vaccines | Site pain, fever |
| What are rare adverse effects with vaccines | GBS, allergic, clotting |
| What are some major contraindications to receiving vaccinations | GBS within 6w |
| Is anything more common with flu vaccine and RSV vaccine | GBS |
| Does egg allergy matter for flu vaccine | Not anymore |
| Is a clot history a contraindication to all covid vaccines | No |
| If a patient has an adverse effect to a vaccine, what must you do | report it |
| Does timing and completeness of a vaccination schedule matter in regards to its success | yes |
| Where can you find current immunization schedules for <18 | AAP and CDC |
| Where can you find current immunization schedules for >18 | CDC |
| Can inactivated vaccines give you the disease | No |
| Can live vaccines give you the disease | Yes but unlikely unless immunocompromised |
| What are the 3 live vaccines we use | Rotavirus, MMR, Varicella, (Nasal Flu) |
| What can you do to check someone's immunity after vaccination | Titer |
| Are titers done on everyone for every vaccination | No |
| Who gets rotavirus vaccine | <8m |
| How is the rotavirus vaccine given | oral |
| Does it matter which pneumococcal vaccine people get | Yes- what it covers for changes |
| Who is RSV vaccine indicated for | Mothers and Older adults |
| What RSV product do we give kids <8 m during first RSV season | Monoclonal antibodies |
| Meningococcal vaccines timeline | 11/12 and again at 16 |
| Do we have consistent recommendations on when to give COVID vaccine | No |
| Are all COVID vaccines equal | No |
| What vaccine is recommended that we get early | Flu |
| Special about flu vaccine the first year you get it | You get two |
| Is the influenzas or COVID vaccine the same each year | no based on the strain in Australia |
| What age group do we give HPV vaccine | 9-26 |
| What are the vaccine options for tetanus | Tdap, td, DTap |
| Which tetanus vaccine do women get when they're pregnant | Tdap |
| 3 most important vaccines for someone with asplenia | Tdap, MMR, VAR, Pneumococcal, HIB, IPV |
| What are some of the vaccines indicated in patients once they turn 50 | Zoster, pneumonia |
| What vaccine is indicated in patients once they turn 60 | RSV |
| What is the preferred treatment of choice for ADHD in kids under 6 | Behavioral therapy |
| What is the preferred treatment of choice for ADHD kids over 6 | Stimulant/meds |
| What is the downside to the preferred agents as a drug class for ADHD | Cardiac toxicity, growth, abuse potential |
| What to monitor while on stimulants | weight, if pt taking, heart function, abuse of med |
| What do you need to screen for before proscribing stimulants | cardiac history and psych history |
| What are the two subclasses within the stimulants | Methylphenidate and Amphedimines |
| What is the typical duration for immediate release stimulants | 4-6hr |
| Are there any abuse deterrents stimulants | No |
| What are drug holidays | stopping medication on purpose for small amount of time |
| Can you do drug holidays with all ADHD medications | no just stimulants |
| What are non-stimulant options for ADHD | Selective norepinephrine reuptake inhibitors and central alpha 2 agonists |
| What are some concerns with atomoxetine | very similar to stimulant so not any better for the heart |
| Who would be a good candidate for the selective norepi reuptake inhibitors | Those with heart conditions or SUD |
| Who would be a good candidate for the central alpha 2 agonist | Those with a cardiac history or turrets |
| Central alpha 2 agonists concerns | worry with withdraw |
| What can you use to screen for amphetamine use | drug screen |
| What can you use to screen for methylphenidate use | blood |
| What level of proscribing are stimulants | C2- can only give 30d at a time |
| What are appropriate pediatric references for neonates | Neofax |
| What are appropriate pediatric references for infants | Neo or up to date |
| What are appropriate pediatric references for older kids | Up to date |
| Is there a list that tells you which meds to use with caution/avoid in kiddos | Kidzlist- does not have everything |
| What information is necessary for a prescription to be complete | Dx, pt info, what you want them to get in full detail |
| What do you need to know to be able to appropriately include quantity on a pediatric prescription | mg/mL dose |
| Where can you find mixing and storage information for meds | Uptodate and insert |
| When might paper prescriptions be preferred/necessary | controlled substances, PT, OT, Speech, sytem down |
| What special about prescribing controlled substances | Restrictions and they are good for less time |
| What can be done to reduce prescribing errors | Follow a method |
| Neo adjunctive chemotherapy | Before surgery |
| What is adjunctive chemotherapy | After surgery |
| What is the main mechanism of action of traditional chemo | Kill rapidly dividing cells |
| What is different in the MOA of targeted therapy | specific target focused |
| What is the MOA of immunotherapy | Utilizing their immune system |
| What are the main adverse effects of traditional chemotherapy | N/V, mucasitis, bone marrow, toxic |
| What are the main adverse effects of immunotherapy | Inflammation |
| How can you predict adverse effects of targeted therapy | Based on target |
| Do all chemotherapy agents cause hair loss, vomiting, nail changes, and bone marrow toxicity | No |
| How do you pick a chemo regimen | Guidelines |
| If someone is receiving an agent for a specific target what are they receiving | Targeted therapy |
| Is targeted therapy an option for everyone | No- they don't have markers to attack |
| What can you do for nausea and vomiting w chemo | prophylactic antiemetic for several days |
| What can you do to reduce infection risk based on duration of neutropenia | prophylactic for bugs |
| Are any of the cancer risk factors modifiable | Smoking #1, sun, alcohol, eating, exercise |
| What should you do when you see an elderly patient and begin to evaluate their medication list | Review, eval, adjust, simp |
| What resources can you use to evaluate the medications for appropriateness for geriatrics | Beers |
| What accounts for approximately 25% of acute medical events in the geriatric populations | drug AE |
| Is the number of medications someone is on linked to the number of AE | yes 5+ meds |
| What do we call multiple medications for one indication of "lots of meds" | Polypharmacy |
| What happens beside ADME changes that may make the elderly more sensitive to adverse effects | Decreased ability to compensate |
| What is the difference about metabolism in the elderly | decreased metabolism |
| What is also different in elderly that metabolism impacts | More drug drug interactions |
| What is different about excretion and renal elimination in the elderly | Not great, need to adjust |
| What are the main medication classes you use caution w in the elderly | anticholinergic, abx, opioids, warfrin |
| What are the main side effects you're wanting to avoid due to not being tolerated well in the elderly | drops |
| Is there a way you can decide what medications are preferred for certain indications in the elderly | List |
| What is left untreated in approximately 80% of elderly | depression and increased suicide rate |
| How should you approach medications adherence in the elderly population | why becomes more important |
| What should you ask patients to bring to their visits | med bottle, list, talk through |
| Gram negative bugs w antibiotics tend to make patients | sicker before they get better |
| Gram negative bugs have... that gram positive do not | Lipopolysacharide |
| Gram positive cocci | Staph Strep Enterococcus |
| Gram positive rods | Bacillus, Clostridium, Corynebacterium, Listeria |
| Gram negative cocci | Neisseria and Moraxella |
| Gram negative bacilli | Enteric, Pseudomonas, E. Coli, H. Flu, Bordetella, Legionella, Pasturella |
| Atypical bacteria | Mycobacterium, Treponema, Leptospira, Chlamydia, Rickettsia |
| Mycobacterium bugs | TB and leprosy |
| Which main categories of bugs typically cause skin and soft tissue infections | Gram Positive Cocci |
| Where do we typically see atypical bacterial infections | Lungs |
| Most common gram positive bugs that cause infection | SSE |
| What are the most common gram negative cocci that cause infection | Neisseria and M cat |
| Most common gram negative rods that cause infection | enteric and others |
| What type of infections do gram negative bugs typically cause | pulmonary mainly |
| What main category of bugs typically cause UTI | Both Gram - and Gram + |
| Which main category of bugs typically cause oral or intrabdominal infections | Anaerobe |
| Penicillin cover | Strep and Enterococcus |
| Aminopenicillins cover | Strep and Enterococcus |
| Anti-staph penicillin cover | Staph and Strep |
| Ampicillin-sulbactam covers | All but Pseudomonas and atypicals |
| Pipercillin-Tazobactam cover | All but atypicals |
| Amoxicillin-clavulanate covers | All but pseudomonas and atypicals |
| Penicillins | Penicillin G and Penicillin V |
| Aminopenicillins | Amoxicillin and Ampicillin |
| Anti-staph penicillin | Nafcillin, Oxacillin, and Dicloxacillin |
| What do none of the cephalosporins cover | Enterococcus |
| Cephalosporin 1st gen | Cefadroxil, Cefazolin, Cephalexin |
| Cephalosporin 1st gen cover | Staph, Strep, Enterics |
| Cephalosporin 2nd gen | Cefaclor, Cefotetan, Cefoxitin, Cefprozil, Cefuroxime |
| 2nd Gen Ceph that cover anaerobes | Cefotetan and Cefoxitin |
| 2nd gen cephalosporins cover | Staph, Strep, Enterics, and H. flu/M. Cat |
| 3rd Gen cephalosporins | Cefdinir, cefditoren, cefixime, cefotaxime, cefpodoxime, ceftazidime, ceftibuten, ceftriaxone |
| 3rd gen cephalosporin cover | Staph, strep, Enterics, H. Flu/M cat |
| 3rd gen cephalosporin that covers pseudomonas | Ceftazidime |
| 4th gen cephalosporin | Cefepime |
| 4th gen cephalosporin covers | pseudomonas, Strep, Staph, Enterics, H.Flu/Mcat |
| 5th gen cephalosporin | Ceftaroline |
| 5th gen cephalosporin covers | MRSA, Strep, Enterics, H.Flu/Mcat |
| Carbapenems | Meropenem, Imipenem, Ertapenem |
| Ertapenem does not cover... that other carbapenems do | Pseudomonas, Enterococcus, Acinetobacter |
| consider the big gun betalactam | Carbapenems |
| Carbapenems cover | Everything but atypicals (unless you're ertapenem) |
| What do carbapenems not cover | MRSA, VRE, atypicals |
| When is monobactam used | Gram - coverage and allergic to penicillin |
| Fluoroquinolones 1st gen | Not clinically relevant anymore |
| Fluroquinolone 2nd gen | Ciprofloxacin |
| Ciprofloxacin cover | GU, pseudomonas |
| 3/4th gen Fluroquinolone | Levofloxacin and Moxifloxacin |
| 3rd and 4th gen used for | Lungs |
| Moxifloxacin | anaerobic coverage |
| Ciprofloxacin and Levofloxacin both cover | Pseudomonas |
| Dont use.... with fluroquinolones | oral mag, calcium, and zinc |
| Cardiac side effect concern with fluroquinolones | QTC prolongation |
| Concerns with fluoroquinolones | QTC and Tendon rupture |
| Macrolides are best for | atypicals |
| Macrolides | Clarihromycin, Azithromycin, erythromycin |
| What do macrolides no cover | Strep pneumonia |
| Are macrolides ever used for something other than antimicorbial | GI azithromycin for motility |
| Odd MRSA coverage | Sulfonamides, Tetracyclines, Glycopeptides, Lipopeptides, Oxazolidinones |
| Major side effects with sulfamethoxazole-trimethoprim | SJS, rash, BM supression |
| What are tetracyclines known to be great at covering | Atypicals |
| Sulfamethoxazole-trimethoprim great at covering | Gram negative (UTI) |
| Which agents are not good due to tooth discoloration | Tetracycline |
| Which agents cover DRE | Daptomyocin, Linzolid |
| What do you not use daptomyocin to treat | Pulmonary infection |
| What types of organisms does clindamycin cover | Gram + and anaerobes |
| What side effect will patients likely complain of with clindamycin | Diarrhea |
| What bugs are aminoglycosides typically used to treat | Gram negative |
| What toxicities do you worry about with aminoglycosides | Renal and hearing |
| What does metronidazole cover, it typically added to ciprofloxacin or cefepime to gain coverage | Anaerobes |
| What are two counseling points you may want to warn patients about with metronidazole | alcohol and metallic taste |
| What antibiotics are preferred for gram-positive infections | Beta lactams |
| Antibiotics that ONLY cover anaerobes | Metronidazole and Clindamycin |
| Antibiotics for atypical bacterial infections | Tetracycline, Fluoroquinolones, Macrolides |
| What infection do you not use daptomycin for | Pulmonary |
| What to worry about with clindamyocin | C diff |
| What is oral vanc used for | C. diff |
| What is IV vanc used for | MRSA |
| Are antivirals always just for treatment | No sometimes prophylaxis |
| What to use for HSV or VZV | Acyclovir or valcyclovir |
| What to use for CMV | Valganciclovir, cidofovir, or foscarnet |
| What do we worry about with acyclovir and valacyclovir | Crystal formation in kidneys |
| What do we worry about with valganciclovir, cidofovir and foscarnet | hemolytic toxicity and renal toxicity |
| Mycobacteria classification | Aerobic and require acid fast staining |
| How long do we treat latent TB | 3-4 months (preferred) |
| How many phases of treatment are there for latent TB | 2 |
| How long do we treat active TB | 4 months minimum |
| Are there phases of treatment for active TB | intense and continuation |
| What are the rifamycin based regimens know for | Drug interactions |
| What is isoniazid known for | Peripheral neuropathy |
| Directly observed therapy (DOT) | Trained staff that have to watch the patient take their medication and assess for toxicities |
| Do we care if patients take their treatment for active or latent TB | yes |
| How can we improve adherence and therefore protect public health with TB meds | DOT and pick best medication for patient |
| M kansaii infection | TB like |
| M avium infection | TB like |
| Are other mycobacterium other than TB a big deal to get | yes |
| Is MAC or TB treated longer | MAC |
| What kind of patient may require IV therapy for 8-12 weeks | Cavitary or Nodular infection |
| Are all fungal infections treated the same | No |
| What type of infection is PJP | fungal |
| How do you treat PJP | Bactrim |
| Do you ever give anything you wouldn't normally give someone with an active infection to someone with PJP | Steroids if struggling to breath |
| Are all candidal infections sensitive to azoles | No |
| What we think about with azoles | hepatotoxicity, QTC prolongation, drug interactions |
| Treatments for fungal | 1- azoles, 2- Echinocandins, 3- Amphotericin |
| Types of medications that cause immunosuppression | Steroids, chemo, Monoclonal antibody therapy |
| Are traditional antibiotics used to treat mycobacteria | No |
| What types of drugs do we use for mycobacteria | RIPE |
| What are side effects of RIPE meds | hepatotoxicity |
| What can you give to reduce the risk of isoniazid causing peripheral neuropathy | B6 |
| How long do you treat mycobacterium avium | 12 months |
| What types of fungi are we most worried about | Candidia kruzia and gilbrata |
| Can you treat kruzia with fluconazole | no |
| Is Gilbrata sensitive to all azoles | No must do susceptibility test |
| Azole AE | Drug interactions, QTC, hepatotoxicity |
| Side effect of amphotericin B | rigors |
| What do we use to help prevent the side effects of amphotericin | Fluids pre and post as well as premedicate |
| What drug may we give with amphotericin B | Flucitzine |
Created by:
kendallmk