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Top drug list S26
| Question | Answer |
|---|---|
| Effient | Prasugrel Thienopyridine P2Y12 antag Antiplatelet Irreversibly inh platelet act via binding to P2Y12 ADP rec class on platelets |
| Brilinta | Ticagrelor Thienopyridine P2Y12 antag Antiplatelet Reversibly binds P2Y12 ADP rec on platelets |
| Bayer | Aspirin Antiplatelet agent Analgesic and Antiplatelet Inh COX-1 and COX-2, leads to dec thromboxane A2 and platelet aggregation |
| Imdur | Isosorbide mononitrate Nitrate Cardiovascular agent/antianginal Relaxes vascular smooth muscle by inc NO |
| Entresto | Valsartan/sacubitril ARB/neprilysin inh Cardiovascular agent/antianginal ARB and inh neprilysin, causing vasodilation and natriuresis |
| Activase | Alteplase Thrombolytic agent Plasminogen to plasmin, which degrades fibrin in thrombi |
| TNKase | Tenecteplase Thrombolytic agent Plasminogen to plasmin, degrades fibrin in thrombi |
| Zyrtec | Cetirizine H1 antag, 2nd gen Antihistamine, Inh peripheral H1 rec |
| Claritin | Loratadine H1 antag, 2nd gen Antihistamine Inh peripheral H1 rec |
| Benadryl | |
| Diphenhydramine H1 antag, 1st gen Antihistamine Inh peripheral and central H1 rec | |
| Atarax, Vistaril | Hydroxyzine H1 antag, 1st gen Antihistamine Inh peripheral and central H1 rec |
| Allegra | Fexofenadine H1 antag, 2nd gen Antihist Inh peripheral H1 rec |
| Benadryl | |
| Mobic | Meloxicam NSAID analgesic Inh COX 1 and 2, dec prostaglandin formation |
| Aleve | Naproxen NSAID analgesic Inh COX 1 and 2, dec prostaglandins |
| Advil Motrin | Ibuprofen NSAID analgesic Inh COX 1 and 2, Dec prostaglandins |
| Voltaren | Diclofenac NSAID Analgesic Inh COX 1 and 2, Dec prostaglandins |
| Celebrex Elyxyb | Celecoxib Cox 2 selective NSAID analgesic Inh COX2, Dec prostaglandins |
| Toradol | Ketorolac NSAID Analgesic Inh COX1 and 2, Dec prostaglandins |
| Zohydro ER (cap) Hysingla ER (tab) Norco (w APAP) | Hydrocodone Opioid analgesic Analgesic, opioid Binds mu-opioid rec in CNS, alters resp to pain |
| OxyContin Roxicodone | Oxycodone Opioid analgesic Analgesic, opioid Binds mu-opioid rec in CNS, alters pain resp |
| Ultram | Tramadol Opioid analgesic Analgesic, opioid Binds mu-opioid rec in CNS, alters pain resp and inh reuptake of norepinephrine and serotonin |
| Tylenol | Acetaminophen Analgesic, antipyretic Inh prostaglandin syn in CNS and acts in hypothalamic heat regulating center |
| Prilosec | Omeprazole PPI Anacid Inh H/K ATPase enzyme system in GI, red gastric acid |
| Protonix | Pantoprazole PPI Anacid Inh H/K ATPase enzyme system in GI |
| Nexium | Esomeprazole PPI Anacid Inh H/K ATPase in GI |
| Pepcid | Famotidine H2 rec antag Anacid Inh H2 of GI, dec gastric acid |
| Zofran | Ondansetron Selective 5-HT3 rec antag Antiemetic Inh 5-HT3, blocks serotonin in peripheral vagus nerve and central chemoreceptor trigger zone |
| Zithromax Z-Pak | Azithromycin Macrolide Antibiotic Inh protein synthesis by binding to 50S ribosomal subunit, prevents mRNA transcription |
| Amoxil Trimox | Amoxicillin Beta lactam Antibiotic Inh cell wall syn by binding to penicillin binding proteins, causing lysis |
| Augmentin | Amoxicillin-Clavulanate Beta lactam, beta lactamase inh combo Antibiotic Amox inh cell wall by binding to penicillin binding proteins, clavulanic acid inh beta lactamases from breaking amox |
| Cleocin | Clindamycin Lincosamide Antibiotic Binds 50S subunit, prevents mRNA transcription |
| Flagyl | Metronidazole Nitroimidazole Antibiotic Disrupts DNA helicase struc, inh nucleic acid syn |
| Cipro | Ciprofloxacin Fluoroquinolone Antibiotic Inh DNA replication and transcription via inh DNA gyrase and topoisomerase 4 |
| Levaquin | Levofloxacin Fluoroquinolone Antibiotic Inh DNA replication and transcription by inh DNA gyrase and topoisomerase 4 |
| Pen-VK | Penicillin Beta lactam Antibiotic Binds penicillin binding proteins, destroys cell wall |
| Macrobid | Nitrofurantoin Nitrofuran Antibiotic Converts to reactive metabolites, inh ribosomes and synthesis |
| Bactrim | Sulfamethoxazole/trimethoprim Sulfonamide Antibiotic Inh dihydrofolic acid syn, decreases DNA replication |
| Firvanq Vancocin | Vancomycin Glycopeptide Antibiotic Blocks glycopeptide polymerizaton, inh cell wall syn |
| Vibramycin | Doxycycline Tetracycline Antibiotic Inh 30S subunit, inh mRNA trans. |
| Rocephin | Ceftriaxone Cephalosporin Antibiotic Binds penicillin binding proteins, inh cell wall syn |
| Keflex | Cephalexin Cephalosporin Antibiotic Inh cell wall syn via binding penicillin binding proteins |
| Omnicef | Cefdinir Cephalosporin Antibiotic Inh cell wall syn via binding penicillin binding proteins |