Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Chapter 2
Definitions
| Term | Definition |
|---|---|
| Low Dose-Effect Curve | Measuring the response to the dose of the drug |
| Potency | The amount of drug required to produce an effect |
| Efficacy | related to the maximal effect of a drug regardless of dose |
| Therapeutic action/effect | the intended or desired results |
| Therapeutic range | range between the dose causing the minimum effect and the dose causing the minimum adverse effect |
| Therapeutic index (TI) | number that determines the safety of a drug. (the greater the TI, the safer the drug) |
| Efficacy | is the maximum intensity of effect or response that can be produced by a drug |
| Renal | Kidney |
| Hepatic | Liver |
| Biotransformation | Is the body’s way of changing a drug so that it can be more easily excreted by the kidneys. |
| Tolerance | the need for an increasingly larger dose of the drug to obtain the same effects as the original dose |
| Duration | is the length of a drug’s effect |
| Half-Life | the half-life of a drug is the amount of time that passes for its concentration to fall to half (50%) of its original blood level. |
| Median effect dose (ED50) | is the dose required to produce a desired clinical effect in 50% of test subjects. A low effective dose is preferred because it means less drug is needed to achieve the desired therapeutic effect. |
| Lethal Dose (LD50) | is the amount of a substance that causes death in 50% of a test population. A lower LD means the substance is more toxic |
Created by:
l.carter9