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A&P Lecture 1 pt. 2

A&P Lecture 1 Week 1 pt. 2

TermDefinition
Epithelial tissues: sheet of closely adhering cells, one or more cells thick, with upper surface exposed to environment or internal space Has a top and a bottom - because they have proteins embedded in the membrane
ET also: Covers body surfaces and lines body cavities Constitutes most glands Avascular (does not have blood vessels) - nourished by ct Is usually nourished by underlying connective tissue
Functions of epithelial tissue Protect-deeper tissues from injury/ infection Secrete -produce/release mucus, sweat, enzymes, hormones Excrete-void waste from issues Absorb-absorb chemical Filter-all substances leave body are filtered by ET Sensation-nerve ending detect stimuli
General structure of epithelial: cells are closely pact together, have small amount of extracellular material High rate of mitosis in cells near CT Rests on a basement membrane Has collagen, glycoproteins, other protein-carbohydrate complexes Anchors the epithelium to CT below
basement membrane (layer between an epithelium and an underlying connective tissue)
Basal surface— surface facing the basement membrane
Apical surface— surface that faces away from the basement membrane
Lateral surface— surface between the basal and apical surface, the “sidewall”
Epithelia classified by number of cell layers 1 layer: simple
Stratified epithelia have cells on top of others, so not all contact the basement membrane 2+ layers: stratified
Squamous cells: similar to a cracked egg - egg yolk as the nucleus
Simple squamous epithelium: thin, scaly cells Single row of thin cells Permits rapid diffusion or transport of substances Secretes serous fluid Locations: alveoli, glomeruli, endothelium, and serosa
Simple squamous ET Main function & location: Function: diffusion (of gases) location: lungs, capillaries
Simple cuboidal epithelium: squarish or round cells Single layer of square or round cels Absorption and secretion, mucus production, and movement Locations: liver, thyroid, mammary and salivary glands, bronchioles, and kidney tubules
Simple cuboidal ET main function and location: function: absorb & secrete location: kidney, glands (endocrine glands)
Simple columnar epithelium: Single row of tall, narrow cells oval nuclei in basal half of cells Brush border of microvilli, sometimes ciliated, may possess goblet cells Absorb/secrete of mucus smooth top Locations: lining of GI tract, uterus, kidney, and uterine tubes
Simple columnar ET main function and location function: absorb & secrete location: GI tract & fallopian tubes
whenever the shape changes the function also changes Everytime we change anatomy of something we change the function
In the fourth type, pseudostratified columnar, not all cells reach the surface but all reach the basement membrane Falsely appears stratified, as some cells taller than others
Goblet cells— wineglass-shaped mucus-secreting cells in simple columnar and pseudostratified epithelia
Ciliated pseudostratified columnar epithelium looks multilayered, but all cells touch basement membrane Nuclei at several layers Has cilia and goblet cells Secretes and propels mucus Locations: respiratory tract and portions of male urethra
Ciliated pseudostratified columnar ET main function and location: function: create and propel mucus location respiratory tract
Cilia on top of pseudostratified is for movement Microvilli on top is for absorption
Stratified epithelia range from 2 to 20 or more layers of cells Some cells rest directly on others; only the deepest layer attaches to the basement membrane
A fourth type, urothelium, is unique to the urinary tract - previously called transitional epithelium
Epidermis: outside layer of the skin
Keratinized stratified squamous epithelium: Multiple cell layers; cells become flat and scaly toward surface Resists abrasion; retards water loss through skin; resist penetration by pathogenic organisms Locations: epidermis, palms and soles heavily keratinized
Keratinized stratified squamous ET main function and location: function: resists friction, prevent water loss location: epidermis, oral cavity, and vagina
Nonkeratinized stratified squamous epithelium: Same as keratinized epithelium without surface layer of dead cells Resists abrasion and penetration of pathogens Location: tongue, oral mucosa, esophagus, and vagina
Stratified cuboidal epithelium: Two or more cell layers; surface cells square or round Secretes sweet, produces sperm, and produces ovarian hormones Locations: sweat gland ducts; ovarian follicles and seminiferous tubules
Stratified cuboidal ET main function and location: function: produces sweat, produce ovarian hormones location: sweat gland, ovary
Stratified columnar epithelium: location: mammary glands
Urothelium: Multilayered epithelium with surface cells that change from round to flat when stretched Allows for filling of urinary tract Locations ureter and bladder
Urothelium ET main function and location: expansion of urinary bladder urinary bladder
Pseudostratified: fuzzy top and messy nucleus
Connective tissue: most abundant, widely distributed, variable type of tissue in which cells occupy less space than matrix Most cells are not in direct contact w each other highly variable vascularity Loose CT have many blood vessels Cartilage has no blood vessels
Functions of connective tissues: organ binding— bone to another, muscles, skin, organs in place Support— framework of organs Physical —cushion delicate organs Immune — cells attack foreign Movement—bones Storage— fat, calcium, phosphorus Heat —brown fat blood Transport
Fibrous connective tissue: Classified together because fibers are so conspicuous Components of fibrous connective tissue:
Cells breakdown: Blast cells: builder cells (fibroblast, builds fibers) Osteo: bones (osteoblast, builds bones) Phage: to consume Macro-big -cyte: is an adult cell in interphase
Cells: Fibroblasts produce fibers, ground substance of matrix Macrophages arise from monocytes; phagocytize foreign material, activate immune system when they sense foreign matter (antigens) Leukocytes, or white blood cells (WBCs) function in immune defense
cell examples again Neutrophils attack bacteria; lymphocytes react against bacteria, toxins, Plasma cells from lymphocytes, synthesize Antibodies Mast cells Secrete heparin to inhibit clotting histamine dilate blood vessels Adipocytes dominate fibrous tissues
Collagenous fibers made of collagen - protein that can absorb water Tough, strong, flexible, and stretch-resistant Called white fibers due to appearance in fresh tissue Less visible in the matrix of cartilage and bone
Collagenous fibers CT main function and location: strong and resistant to stretch Tendons, ligaments, and deep layer of the skin are mostly collagen
Reticular fibers: Thin collagen fibers coated with glycoprotein Form framework of spleen and lymph nodes; part of the basement membranes under epithelia
Reticular fibers CT main function and location: function: framework for storing cells location: Spleen and lymph nodes
Elastic fibers (also known as elastin (protein)) Thinner than collagenous fibers; made of protein elastin Allows stretch and recoil like a rubber band
Elastic fibers CT main function and location: function: that it is stretchy location: Lungs, dermis
Ground substance: featureless substance surrounding cells, usually gelatinous or rubbery Absorbs compressive forces; contains large molecules—GAGs, proteoglycans, glycoproteins
Loose connective tissue: function: mostly ground substance in space surrounding cells location: Types areolar CT and reticular CT
Areolar connective tissue (loose): Loosely organized fibers, abundant blood vessels Possesses all six cell types and fiber types Underlies epithelia, in serous membranes, between muscles, passageways for nerves and blood vessels
Areolar CT main function and location: Function: allow for some stretch and bind structures together Location: under skin, around Neurovascular bundle
Reticular connective tissue (loose) Mesh of reticular fibers and fibroblasts Forms supportive stroma (framework) for lymphatic organs
Reticular CT main function and location: Function: holds cells within organs Location: Found in lymph nodes, spleen, thymus, and bone marrow
Adipose connective tissue (loose) Empty-looking cells with thin margins, nucleus pressed against cell membrane Energy storage, insulation, cushioning, brown fat produces heat
Adipose (fatty) CT main function and location: Function: fat storage (triglyceride) Location: hypodermis (layer of fat), surrounds the kidney
Dense connective tissue: mostly fibers in space surrounding cells Types: dense regular and dense irregular
Dense regular connective tissue: Densely packed, parallel collagen fibers Compressed fibroblast nuclei Elastic tissue forms wavy sheets in some locations Tendons attach muscles to bones and ligaments hold bones together
Dense regular CT main function and location: Function: resists pulling, one-direction Location: tendons, ligaments
Tendons : connects muscle to bone
Ligament: connects bone to bone
Dense irregular connective tissue: Densely packed, randomly arranged, collagen fibers and few visible cells Withstands unpredictable stresses Locations: deeper layer of skin; capsules around organs
Dense irregular CT main function and location Function: resists pulling from many directions Location: dermis
Elastic connective tissue (diff from cartilage) so that the heart can pump and snap back to its original position Some structure in the body with elastin - resistant of pulling forces Able to stretch and recoil
Elastic CT main function and location Function: for the aorta to be stretchy - stretchiness Location: aorta - really big artery with really big walls, nearby the heart - elastic is used
Cartilage - stiff connective tissue w flexible, rubbery matrix matrix is bouncy and gummy Gives the shape to the ear, tip of nose, and larynx No blood capillaries (avascular) Diffusion brings nutrients and removes wastes Heals slowly
types of cartilage vary with fiber composition: hyaline, fibrocartilage, elastic
chondroblast: cartilage cells that produce the matrix
Chondrocytes: cartilage cells that are trapped in lacunae (cavities)
Perichondrium - sheath of dense irregular connective tissue that surrounds elastic and most hyaline cartilage (not articular cartilage) Contains a reserve population of chondroblasts that contribute to cartilage growth throughout life
Hyaline cartilage: Clear, glassy appearance becuz of fineness of collagen fibers Provides shapes, make things bouncy, provide support Eases joint movement, holds airway open, moves vocal cords, growth of juvenile long bones - trachea, larynx, fetal skeleton
Hyaline cartilage CT main function and location: Function: structure, joint movement Location: joints, trachea
Elastic cartilage: Cartilage containing abundance of elastic fibers Covered with perichondrium Provides flexible, elastic support Locations: external ear and epiglottis
Elastic cartilage CT main function and location: Function: bend & snap Location: ear and epiglottis (covers your feeding tube)
Fibrocartilage: Cartilage containing large, coarse bundles of collagen fibers Resists compression and absorb shock Locations: public symphysis, minisci, and intervertebral discs
Fibrocartilage CT main function and location: Function: resist compression Location: fibrocartilage discs of spine
Bone (matrix is hardened) Cylinders that surround central (osteonic) canals that run longitudinally through shafts of long bones Blood vessels and nerves travel through central canal Bone matrix deposited in concentric lamellae
Bone CT main function and location: Function: structure, provides protection for squishy organs Location: skeleton
Blood - Connective Tissue fluid connective tissue that travels through tubular blood vessels - looks at the cells and matrix Transports cells and dissolved matter from place to place Contains formed elements suspended in a liquid ground substance called blood plasma
Formed elements include: Erythrocytes (red blood cells, RBCs)—transport O2 and CO2 Leukocytes (white blood cells, WBCs)—defend against infection and disease Examples: neutrophils, eosinophils, basophils, lymphocytes, monocytes Platelets—cell fragments involved in clotting
Blood CT main function and location: Transport (gases, nutrients, hormones) In the heart, in blood vessels
Blood smear: Erythrocytes appear as pale pink discs with light centers Leukocytes are slightly larger and have variously shaped nuclei Platelets are small cell fragments with no nuclei
Excitability: ability to respond to stimuli by changing membrane potential Developed to highest degree in nervous and muscular tissues (excitable tissues) Excitation founded in charge difference (voltage) across membrane called the membrane potential
excitability In Nerve cells: changes in voltage (increased excitability) (really fast cell communication) result in rapid transmission of signals to other cells
excitability In muscle cells, changes in voltage (increased excitability) result in contraction, shortening of cell
Nervous tissue: neuron: conducts signals Location: brain, spinal cord, nerves
Muscular tissue - another excitable tissue: specialized to contract when stimulated, exerting a physical force on other tissues, organs, or fluids Important source of body heat Three types: skeletal, cardiac, and smooth
Glial cells: support cells - supports the neuron, feed, clean, guide growth
Skeletal muscle: Made of muscle fibers - long thin cells Most skeletal muscles attach to bone Contains multiple nuclei adjacent to plasma membrane Has striations/stripes Is voluntary
Voluntary: conscious control over skeletal muscles
Striations stripes due to orientation of proteins (protein overlapping with one another) - alternating dark and light bands
Skeletal muscle MT main function and location Function: moves the body Location: connected to the skeleton
Cardiac muscle: Spaces around nuclei, stripy short Limited to the heart wall Cardiomyocytes are short and branched with one centrally located nucleus Intercalated discs join cardiomyocytes end to end Striated and involuntary (not under conscious control)
Cardiac muscle MT main function and location Function: heart pumping Locations: only in the heart
Smooth muscle Looks like smeared fingerpaint - if not stripy it is smooth muscle Made of short, fusiform-shaped cells Cells have one central nuclei, no striations Involuntary function most is visceral muscle
Visceral muscle - making up parts of walls of hollow organs
Smooth muscle MT main function and location Function: involuntary movement - happens automatically Location: blood vessels, hollow organs, etc
Created by: Katepop10
 

 



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