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BDK: ID 4
25-26 LIST
| GENERIC | BRAND | CATEGORY | INDICATION | SIDE EFFECTS | BOXED WARNING/NOTES |
|---|---|---|---|---|---|
| Terbinafine | Lamisil | Allylamine antifungal | Onychomycosis | nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache | --- |
| Fluconazole | Diflucan | Azole antifungal | Vulvovaginal candidiasis, oropharyngeal candidiasis, invasive candidiasis | nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases | --- |
| Ketoconazole | Nizoral | Azole antifungal | Tinea infections | nausea, abdominal pain, diarrhea, QTc prolongation, increased hepatic transaminases | serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation have occurred; may cause QTc prolongation and drug interactions leading to QTc prolongation |
| Nystatin (Oral) | --- | Polyene antifungal | Oropharyngeal candidiasis | phlebitis, diarrhea, vomiting, anemia, fever | --- |
| Nystatin (Topical) | Nystop | Polyene antifungal | Cutaneous and mucocutaneous fungal infections | burning, itching | only use oral solutions for thrush |
| Micafungin | Mycamine | Echinocandin antifungal | Invasive candidiasis | no major side effects | --- |
| Betamethasone and clotrimazole | Lotrisone | Glucocorticoid and azole antifungal | Cutaneous fungal infections | burning, itching, dryness, skin atrophy | do not use for diaper dermatitis; adrenal suppression with long-term use over large areas of skin |
| Oseltamivir | Tamiflu | Neuraminidase inhibitor antiviral | Influenza | nausea, vomiting, neuropsychiatric events (i.e., confusion, delirium, hallucinations) in pediatric patients (rare) | --- |
| Acyclovir | Zovirax | Antiviral | Herpes simplex virus | nausea, increased hepatic transaminases, crystalluria | vesicant |
| Valacylovir | Valtrex | Antiviral | Herpes simplex virus | nausea, increased hepatic transaminases | --- |
| Nirmatrelvir + ritonavir | Paxlovid | Antiviral | COVID-19 | diarrhea, dysgeusia | significant drug interactions; strong CYP3A inhibitor |
| Remdesivir | Veklury | Antiviral | COVID-19 | hyperglycemia, renal impairment | --- |
| Emtricitabine + tenofovir disoproxil fumarate | Truvada | Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) | HIV Infection, PreP, PEP | decreased bone mineral density, kidney injury, nausea, diarrhea | post treatment acute exacerbation of hepatitis B, risk of drug resistance with use for preexposure prophylaxis |
| Emtricitabine (NRTI) + tenofovir alafenamide (NRTI) + bictegravir (INSTI) (PO) | Biktarvy | Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) and Integrase strand transfer inhibitor (INSTI) | HIV Infection | increased serum bilirubin, headache, weight gain, insomnia, diarrhea, nausea | post treatment acute exacerbation of hepatitis B Other Notes: take oral INSTIs 2 hours before or 6 hours after products containing calcium, aluminum, magnesium, or iron |