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CNS 2
| Pharmacologic Category | Generic Name | Brand Name | Classification | Common Indications | EK |
|---|---|---|---|---|---|
| CNS stimulant | Dexmethylphenidate (PO) | Focalin, Focalin XR | CS-II | ADHD | Key Side Effects: insomnia, headache, anxiety, weight loss, decreased appetite, hypertension US Boxed Warnings: high potential for abuse Other Notes: CI within 14 days of MAOI |
| CNS stimulant | Dextroamphetamine and amphetamine (PO) | Adderall, Adderall XR | CS-II | ADHD, Narcolepsy | Key Side Effects: insomnia, headache, anxiety, weight loss, decreased appetite, hypertension US Boxed Warnings: high potential for abuse Other Notes: CI within 14 days of MAOI |
| CNS stimulant | Lisdexamfetamine (PO) | Vyvanse | CS-II | ADHD | Key Side Effects: insomnia, headache, anxiety, weight loss, decreased appetite, hypertension US Boxed Warnings: high potential for abuse Other Notes: CI within 14 days of MAOI |
| CNS stimulant | Methylphenidate (PO, Transdermal) | PO: Concerta, Ritalin Patch: Daytrana | CS-II | ADHD, Narcolepsy | Key Side Effects: insomnia, headache, anxiety, weight loss, decreased appetite, hypertension US Boxed Warnings: high potential for abuse Other Notes: CI within 14 days of MAOI |
| Selective alpha 2a agonist | Guanfacine (PO) | Intuniv | ADHD, HTN | Key Side Effects: bradycardia, hypotension, sedation, skin rash, xerostomia, constipation Other Notes: do not abruptly discontinue | |
| Dopamine agonist | Pramipexole (PO) | Mirapex | Parkinson's disease, RLS | Key Side Effects: nausea, hallucinations, dizziness, drowsiness, compulsive behaviors, orthostasis | |
| Dopamine agonist | Ropinirole (PO) | Requip | Parkinson's disease, RLS | Key Side Effects: nausea, hallucinations, dizziness, drowsiness, compulsive behaviors, orthostasis | |
| Decarboxylase inhibitor (carbidopa), dopamine precursor (Levodopa) | Carbidopa and levodopa (PO) | Sinemet, Sinemet CR | Parkinon's disease | Key Side Effects: nausea, orthostatic hypotension, dyskinesias Other Notes: CI within 14 days of MAOI, CI in narrow-angle glaucoma; do not abruptly discontinue | |
| N-methyl d-aspartate (NMDA) antagonist | Memantine (PO) | Namenda | Dementia | Key Side Effects: constipation, confusion, dizziness, headache | |
| Cholinesterase inhibitor | Donepezil (PO, Transdermal) | PO: Aricept Transdermal: Adlarity | Dementia | Key Side Effects: nausea, vomiting, diarrhea |