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Heterogeneities
| Question | Answer |
|---|---|
| Human body heterogeneitites | - Teeth - Bone - Air cavities - Lungs |
| Man-made heterogeneities | - Mandibular plates - Prostheses - Spinal cord fixation devices - Surgical rods - Stents - Dental fillings - Tracheostomy tubes - Fiducial markers - Breast implants |
| CT-ED file | - Converts CT numbers (HU) to electron density values for the TPS - Bone: 1000, water: 0, air: -1000, soft tissue: 1 |
| Planning considerations | - Don't place an entry beam in line with spinal implants - Contour and override the streaking artefact from dental fillings |
| High-Z | - Material with an atomic number greater than cortical bone - e.g. tungsten, gold, gadolinium |
| 6MV & heterogeneities | - Increased dose proximal to the high-Z material - Reduced distal dose from attenuation |
| 18MV & heterogeneities | - Increased dose proximal to high-Z material - Increased dose distal to high-Z material also, due to pair productions in the metal -> overdosing patient (use lower energies when treating patients with metal implants) |
| iMAR | - Metal artefact reduction - Occurs in CT - Improves image quality and therefore contouring and dose accuracy |
| 3DCRT | - Avoid beams passing through device - Can increase dose to OARs - Non-coplanar approach (depends on ease of planning and delivery, collision risks, portal verification and staff training) |
| IMRT | - Avoid prosthesis - Contour prosthesis and make it a critical structure with a dose constraint - 5-9 beams |
| VMAT | - Contour avoidance sector - Use avoidance sectors (Eclipse) |
| Contouring | - Use different window levels - Check relative electron densities - Contour different components separately |
| AAPM recommendations | - Investigate limitations regarding heterogeneity corrections - MDT must be informed of prostheses prior to sim - Use medical records, surgeon, manufacturer - Beam arrangements that avoid the prosthesis - Use the most physically rigorous algorithm |