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Pharmacology CH 2

Drug Action and Handling

QuestionAnswer
Low Dose-Effect Curve Measuring the response to the dose of the drug
Potency The amount of drug required to produce an effect
Efficacy related to the maximal effect of a drug regardless of dose
Therapeutic action/effect the intended or desired results
Therapeutic range range between the dose causing the minimum effect and the dose causing the minimum adverse effect.
Therapeutic index (TI) number that determines the safety of a drug. (the greater the TI, the safer the drug)
Efficacy is the maximum intensity of effect or response that can be produced by a drug
Renal Kidney
Heaptic Liver
Biotransformation Body changes drug so it can be easily excreted by kidneys
Tolerance Needing a larger dose to have the same effects as original dosage
Duration s the length of a drug’s effect
Half-Life amount of time that passes for its concentration to fall to half (50%) of its original blood level
Median effect dose (ED50) dose required to produce a desired clinical effect in 50% of test subjects. Less drug is needed for therapeutic effect
Lethal Dose (LD50) is the amount of a substance that causes death in 50% of a test population (LOWER IS WORSE)
Created by: user-1983045
 

 



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