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Pharm Def. wk 2
| Term | Definition |
|---|---|
| Low Dose Effect Curve | Measuring the response to the dose of the drug |
| Potency | The amount of drug required to produce an effect |
| efficacy | Is the maximum intensity of effect or response that can be produced by a drug |
| Therapeutic action/effect | the intended or desired results |
| Therapeutic range | range between the dose causing the minimum effect and the dose causing the minimum adverse effect |
| Therapeutic index (TI) | number that determines the safety of a drug. (the greater the TI, the safer the drug) |
| Renal | kidney |
| Hepatic | Liver |
| Biotransformation | is the body’s way of changing a drug so that it can be more easily excreted by the kidneys |
| Tolerance | the need for an increasingly larger dose of the drug to obtain the same effects as the original dose |
| Duration | is the length of a drug’s effect |
| Half-Life | the half-life of a drug is the amount of time that passes for its concentration to fall to half (50%) of its original blood level |
| Median Effect Dose (ED50) | is the dose required to produce a desired clinical effect in 50% of test subjects. A low effective dose is preferred because it means less drug is needed to achieve the desired therapeutic effect |
| Lethal Dose (LD50) | is the amount of a substance that causes death in 50% of a test population. A lower LD means the substance is more toxic |
Created by:
hkelley945